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lüll Omalizumab: where does it fit into current asthma management?Rambasek TE; Lang DM; Kavuru MSCleve Clin J Med 2004[Mar]; 71 (3): 251-61Omalizumab (Xolair), a monoclonal antibody, is a new agent that blocks the allergic cascade at its primary step. This drug offers substantial promise for patients with moderate-to-severe, persistent allergic asthma that is not well controlled. But due to the cost of the drug, limitations on dosage, and available clinical trial data, it is not a first-line therapy. This review discusses how this drug works, which patients will be candidates for it, and the practical aspects of using it.|Algorithms[MESH]|Antibodies, Anti-Idiotypic[MESH]|Antibodies, Monoclonal, Humanized[MESH]|Antibodies, Monoclonal/pharmacology/*therapeutic use[MESH]|Asthma/complications/*drug therapy[MESH]|Humans[MESH]|Immunoglobulin E/*drug effects[MESH]|Omalizumab[MESH]|Rhinitis, Allergic, Seasonal/complications/drug therapy[MESH] |