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Eradication of infectious diseases: its concept, then and now Arita I; Wickett J; Nakane MJpn J Infect Dis 2004[Feb]; 57 (1): 1-6The concept of disease eradication emerged as recently as the mid-20th century. The successful eradication of smallpox resulted in the concept of the extinction of the causative agent in man as well as in the environment, leading to the cessation of all control measures including vaccination. Subsequently, world resources have been invested in global polio eradication and measles eradication in the Western Hemisphere. The former is apparently now at the "end game", the latter, after successful campaign in the Americas, aims at program development worldwide. However, both endeavors are being challenged by delays in schedules, unexpected technical problems, lack of global coordination, and ever-increasing political unrest. It is proposed that disease eradication be redefined as the extinction of the pathogen in man, not in nature, making for a more flexible approach in the post-eradication period. Smallpox eradication was a rare event. That concept is unrealistic in today's world.|*Communicable Disease Control/methods[MESH]|*Communicable Diseases/epidemiology/immunology[MESH]|*Global Health[MESH]|*Vaccination[MESH]|Humans[MESH]|Immunization Programs[MESH]|Measles Vaccine[MESH]|Measles/prevention & control[MESH]|Poliomyelitis/prevention & control[MESH]|Politics[MESH]|Smallpox Vaccine[MESH]|Smallpox/prevention & control[MESH] |
