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lüll Foetal intralobar lung sequestration: antenatal diagnosis and management Chen JS; Walford N; Yan YL; Ong CL; Yeo GSSingapore Med J 2003[Dec]; 44 (12): 630-4OBJECTIVES: The objectives of this study are to discuss the use of ultrasonography for the diagnosis of foetal intralobar sequestration (FILS) antenatally and the management options available for these pregnancies. METHODS: This is a retrospective review of six cases of FILS diagnosed antenatally by two dimensional (2D) and colour Doppler ultrasonography out of a total of 31,508 deliveries over a two-year period at the KK Women's and Children's Hospital. RESULTS: The incidence of FILS in this hospital was 1 in 5,251 deliveries. 2D ultrasonography showed an echogenic lung in all cases. FILS was confirmed by the demonstration of a systemic vessel leading to the affected lung on colour Doppler examination. After counselling, four terminated their pregnancies during mid-trimester, while two continued their pregnancies to term. Confirmation of the terminated cases was by post-mortem. In the two pregnancies that continued, regular growth scans were done to monitor the progression of the condition. Computed tomography confirmed the diagnosis post-delivery. Both were well but one had a resection of the sequestrated lung although he was asymptomatic. Histology also confirmed the diagnosis. CONCLUSION: FILS is a rare anomaly. 2D and colour Doppler ultrasonography are used to diagnose the condition antenatally. Termination of the pregnancy is not always indicated, as there are favourable outcomes from FILS.|*Prenatal Diagnosis[MESH]|Adult[MESH]|Bronchopulmonary Sequestration/*diagnostic imaging/*therapy[MESH]|Female[MESH]|Fetal Diseases/*diagnostic imaging/*therapy[MESH]|Humans[MESH]|Male[MESH]|Pregnancy[MESH]|Retrospective Studies[MESH]|Ultrasonography[MESH] |