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Brain natriuretic peptide in the management of heart failure: the versatile neurohormone de Denus S; Pharand C; Williamson DRChest 2004[Feb]; 125 (2): 652-68Brain natriuretic peptide (BNP), also called B-type natriuretic peptide, is a member of a family of structurally related hormones, the natriuretic peptides. Current data suggest that measurement of BNP plasma concentrations is a useful tool in the diagnosis of acute heart failure in patients presenting to an emergency department with acute dyspnea. Furthermore, BNP constitutes a promising new marker of prognosis after an acute coronary syndrome episode and in patients with chronic heart failure. Nesiritide, the human recombinant form of BNP, is a new vasodilator used in the treatment of acute heart failure that has several potential advantages over current drug therapy.|Adult[MESH]|Aged[MESH]|Biomarkers/blood[MESH]|Critical Illness[MESH]|Emergency Treatment/methods[MESH]|Female[MESH]|Follow-Up Studies[MESH]|Heart Failure/*drug therapy/*physiopathology[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH]|Natriuretic Peptide, Brain/*metabolism/*therapeutic use[MESH]|Randomized Controlled Trials as Topic[MESH]|Risk Assessment[MESH]|Sensitivity and Specificity[MESH]|Severity of Illness Index[MESH]|Treatment Outcome[MESH]|Ventricular Remodeling/*drug effects[MESH] |
