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Leishmanial infection: analysis of its first steps A review de Almeida MC; Vilhena V; Barral A; Barral-Netto MMem Inst Oswaldo Cruz 2003[Oct]; 98 (7): 861-70The first steps in leishmaniasis are critical in determining the evolution of the disease. Major advances have recently been done in understanding this crucial moment. Fundamental research in parasite-vector interaction, parasite biology, insect saliva, and vertebrate host response have shed new light and uncovered a most fascinating and complex moment in leishmaniasis. We review here some of these aspects and we try to connect them in a logical framework.|*Leishmaniasis/immunology/parasitology/transmission[MESH]|Animals[MESH]|Host-Parasite Interactions[MESH]|Humans[MESH]|Immunity, Cellular[MESH]|Insect Bites and Stings/immunology[MESH]|Insect Vectors/*physiology[MESH]|Leishmania/*physiology[MESH]|Mice[MESH]|Models, Animal[MESH]|Psychodidae/*physiology[MESH] |
