Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
Warning: file_get_contents(http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=14665413&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 445
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Localization of mechanosensitive channel TRPV4 in mouse skin Suzuki M; Watanabe Y; Oyama Y; Mizuno A; Kusano E; Hirao A; Ookawara SNeurosci Lett 2003[Dec]; 353 (3): 189-92A transient receptor potential (TRP) family, TRPV4, is a calcium-permeable swell-activated channel, playing a role in cutaneous mechanosensation. To elucidate the localization in the mechanosensitive endings, we found with immunohistochemistry in mice that TRPV4 was expressed both by small (low threshold) and large (high threshold) dorsal root ganglia neurons. In addition to free nerve endings, TRPV4 was specifically located at cutaneous mechanosensory terminals co-localized with neurofilament 200, including Meissner, Merkel, penicillate and intraepidermal terminals but not including hair follicle palisades. The distribution suggests that the sensation of pressure by mechanosensitive TRPV4 channel is transmitted through A- as well as C-fiber.|*Cation Transport Proteins[MESH]|*Membrane Glycoproteins[MESH]|Animals[MESH]|Ganglia, Spinal/cytology/metabolism[MESH]|Immunohistochemistry/methods[MESH]|Intermediate Filament Proteins/metabolism[MESH]|Ion Channels/*metabolism[MESH]|Mechanoreceptors/metabolism[MESH]|Mice[MESH]|Nerve Tissue Proteins/metabolism[MESH]|Neurofilament Proteins/metabolism[MESH]|Neurons/metabolism[MESH]|Peripherins[MESH]|Skin/cytology/*metabolism[MESH]|TRPV Cation Channels[MESH] |