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Function of caveolae in Ca2+ entry and Ca2+-dependent signal transduction Isshiki M; Anderson RGTraffic 2003[Nov]; 4 (11): 717-23The correct spatial and temporal control of Ca2+ signaling is essential for such cellular activities as fertilization, secretion, motility, and cell division. There has been a long-standing interest in the role of caveolae in regulating intracellular Ca2+ concentration. In this review we provide an updated view of how caveolae may regulate both Ca2+ entry into cells and Ca2+-dependent signal transduction|Animals[MESH]|Calcium Channels/metabolism[MESH]|Calcium Signaling/*physiology[MESH]|Calcium/*metabolism[MESH]|Caveolae/*metabolism[MESH]|Cell Membrane/metabolism[MESH]|Inositol 1,4,5-Trisphosphate Receptors[MESH]|Inositol 1,4,5-Trisphosphate/metabolism[MESH]|Muscle, Skeletal/metabolism[MESH]|Receptors, Cytoplasmic and Nuclear/metabolism[MESH]|Time Factors[MESH] |
