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Primary bone lymphoma: radiographic-MR imaging correlation Krishnan A; Shirkhoda A; Tehranzadeh J; Armin AR; Irwin R; Les KRadiographics 2003[Nov]; 23 (6): 1371-83; discussion 1384-7Primary bone lymphoma is an uncommon malignancy that accounts for less than 5% of all primary bone tumors. The radiographic appearances of primary bone lymphoma are variable, and, because the lesion can appear near normal on plain radiographs, a second modality such as bone scintigraphy or magnetic resonance (MR) imaging should be used. Despite this variability, the presence of a solitary, permeative, metadiaphyseal lesion with a layered periosteal reaction on plain radiographs and a soft-tissue mass on MR images, especially in a patient older than 30 years, is highly suggestive of lymphoma. The case for a diagnosis of primary bone lymphoma is further strengthened if the soft-tissue mass and marrow changes are associated with surprisingly little cortical destruction. Primary bone lymphoma has a better prognosis than many other malignant bone tumors; therefore, early identification allows for appropriate treatment. MR imaging not only permits early identification but also depicts the extent of soft-tissue involvement and can be used to assess the outcome of treatment.|*Magnetic Resonance Imaging[MESH]|Adolescent[MESH]|Adult[MESH]|Aged[MESH]|Aged, 80 and over[MESH]|Bone Marrow/diagnostic imaging/pathology[MESH]|Bone Neoplasms/diagnosis/*diagnostic imaging/pathology[MESH]|Child[MESH]|Child, Preschool[MESH]|Female[MESH]|Humans[MESH]|Infant[MESH]|Lymphoma, Non-Hodgkin/diagnosis/*diagnostic imaging/pathology[MESH]|Lymphoma/diagnosis/*diagnostic imaging/pathology[MESH]|Male[MESH]|Middle Aged[MESH]|Periosteum/diagnostic imaging/pathology[MESH]|Tomography, X-Ray Computed[MESH] |
