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lüll Inherited vitamin K deficiency: case report and review of literature Orbak Z; Selimoglu A; Doneray HYonsei Med J 2003[Oct]; 44 (5): 923-7Vitamin K is the cofactor for the hepatic carboxylation of glutamic acid residues in a number of proteins including the procoagulants factors II, VII, IX, and X. The role of vitamin K in normal bone function is not fully understood. Inherited deficiency of vitamin K dependent coagulation factors is a rare bleeding disorder reported only in a few patients. Here we present an 18-month old child who presented with osteopeni due to inherited vitamin K deficiency. While the patient had high bone specific alkaline phosphatase and parathyroid hormone levels and low osteocalcin and bone mineral density values, with the regular supplementation of vitamin K all the mentioned parameters returned to normal values.|Bone Density[MESH]|Bone Diseases, Metabolic/etiology[MESH]|Humans[MESH]|Infant[MESH]|Male[MESH]|Osteocalcin/blood[MESH]|Prothrombin Time[MESH]|Vitamin K Deficiency/blood/complications/*genetics[MESH] |