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lüll Detection of subpigment epithelial neovascularisation in cases of retinal pigment epithelial detachments: a review of the Moorfields treatment trial Pagliarini S; Barondes MJ; Chisholm IH; Hamilton AM; Bird ACBr J Ophthalmol 1992[Jan]; 76 (1): 8-10The entry angiograms of 42 eyes with detachment of the retinal pigment epithelium in a treatment trial of laser photocoagulation were reviewed in a masked fashion by three observers in order to assess the possible presence of subpigment epithelial neovascularisation. Vascularity or avascularity was designated with reference to a list of clues believed to imply the presence of subpigment epithelial neovascularisation. As a predictor of outcome the initial assessment achieved a sensitivity and specificity of 77% and 82% respectively. Despite notable parity of the degree of sensitivity and specificity among the three observers, full agreement on the initial assessments was reached in only 23 eyes (55%), 10 with vascular and 13 with avascular outcome. Of these, only one eye which developed new vessels after 4 years had an outcome which differed from that predicted by classification of the entry angiograms.|Aged[MESH]|Aged, 80 and over[MESH]|Fluorescein Angiography[MESH]|Humans[MESH]|Light Coagulation[MESH]|Middle Aged[MESH]|Neovascularization, Pathologic/*pathology[MESH]|Pigment Epithelium of Eye/blood supply[MESH]|Prognosis[MESH]|Retinal Detachment/diagnosis/*pathology/surgery[MESH]|Retinal Vessels/*pathology[MESH]|Time Factors[MESH] |