Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
DNA methylation and Rett syndrome Kriaucionis S; Bird AHum Mol Genet 2003[Oct]; 12 Spec No 2 (ä): R221-7Methylation of cytosine in human DNA has been studied for over 60 years, but has only recently been confirmed as an important player in human disease. Rett syndrome is a neurological disorder caused by mutations in the MeCP2 protein, which has been shown to bind methylated DNA and repress transcription. This review will focus on experiments addressing the basic properties of MeCP2 and on mouse models of Rett syndrome that are starting to yield insights into this condition.|*Chromosomal Proteins, Non-Histone[MESH]|*DNA Methylation[MESH]|*Repressor Proteins[MESH]|Animals[MESH]|Brain/metabolism[MESH]|DNA-Binding Proteins/genetics[MESH]|Gene Expression Regulation[MESH]|Humans[MESH]|Methyl-CpG-Binding Protein 2[MESH]|Mice[MESH]|Mice, Knockout[MESH]|Mutation[MESH]|Rett Syndrome/*genetics[MESH] |
