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lüll Percutaneous transluminal angioplasty in the treatment of critical limb ischemia Molloy KJ; Nasim A; London NJ; Naylor AR; Bell PR; Fishwick G; Bolia A; Thompson MMJ Endovasc Ther 2003[Apr]; 10 (2): 298-303PURPOSE: To assess the role of percutaneous transluminal angioplasty (PTA) to treat critical limb ischemia (CLI) and to relate the changing experience with endovascular treatment of this condition in a major vascular unit. METHODS: A prospective study was performed involving 110 consecutive patients (57 women; mean age 76 years, range 57-99) undergoing balloon angioplasty for critical limb ischemia in 133 limbs. Outcome at 1 year was examined by case note review or questionnaire to determine survival, amputation-free survival, limb salvage, and CLI recurrence. RESULTS: Technical success was achieved in 105 (79%) of 133 limbs; the overall complication rate was 20% (3.8% major, 16.2% minor). The median follow-up was 15 months (minimum 12). The 12-month limb salvage rate by life-table analysis was 88%. Patients with an initially successful angioplasty had an extremely good outcome (95% 1-year limb salvage). In contrast, the 28 patients with failed angioplasty fared very poorly; a major amputation was required in 10, and death occurred in another 9, leaving only 9 survivors with limbs intact at 1 year. CONCLUSIONS: The results of this study justify the continuing use of PTA as first-line treatment for critical limb ischemia.|*Angioplasty, Balloon[MESH]|Aged[MESH]|Aged, 80 and over[MESH]|Female[MESH]|Follow-Up Studies[MESH]|Humans[MESH]|Ischemia/etiology/*therapy[MESH]|Leg/*blood supply[MESH]|Male[MESH]|Middle Aged[MESH]|Prospective Studies[MESH]|Time Factors[MESH]|Treatment Outcome[MESH] |