Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer s disease cases Hof PR; Bouras C; Buee L; Delacourte A; Perl DP; Morrison JHActa Neuropathol 1992[]; 85 (1): 23-30Head trauma has been associated with the occurrence of Alzheimer's disease and plays a clear role in the etiopathogenesis of the boxers encephalopathy referred to as dementia pugilistica. Neurofibrillary tangles (NFT), one of the pathological hallmarks of Alzheimer's disease are observed in very high densities in the brains of former professional boxers suffering from dementia pugilistica. In Alzheimer's disease, NFT display striking regional and laminar distribution patterns that have been correlated with the localization of neurons forming specific corticocortical connections. In dementia pugilistica cases, NFT were concentrated in the superficial layers in the neocortex, whereas in Alzheimer's disease they predominated in the deep layers. Thus, the association cortex of brains from dementia pugilistica patients demonstrated an inverse NFT distribution as compared to Alzheimer's disease. This finding suggests that a more circumscribed population of cortical pyramidal neurons might be affected in dementia pugilistica than in Alzheimer's disease.|Aged[MESH]|Aged, 80 and over[MESH]|Alzheimer Disease/metabolism/*pathology[MESH]|Amyloid beta-Peptides/analysis[MESH]|Boxing/*injuries[MESH]|Cerebral Cortex/*pathology[MESH]|Dementia/etiology/metabolism/*pathology[MESH]|Humans[MESH]|Immunohistochemistry[MESH]|Male[MESH]|Middle Aged[MESH]|Neurofibrillary Tangles/*pathology[MESH]|tau Proteins/analysis[MESH] |