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  • Caveolae/raft-dependent endocytosis
  • Nabi IR; Le PU
  • J Cell Biol 2003[May]; 161 (4): 673-7
  • Although caveolae are well-characterized subdomains of glycolipid rafts, their distinctive morphology and association with caveolins has led to their internalization being considered different from that of rafts. In this review, we propose that caveolae and rafts are internalized via a common pathway, caveolae/raft-dependent endocytosis, defined by its clathrin independence, dynamin dependence, and sensitivity to cholesterol depletion. The regulatory role of caveolin-1 and ligand sorting in this complex endocytic pathway are specifically addressed.
  • |*Endocytosis[MESH]
  • |Animals[MESH]
  • |Caveolae/*metabolism[MESH]
  • |Caveolin 1[MESH]
  • |Caveolins/metabolism[MESH]
  • |Cholesterol/metabolism[MESH]
  • |Cytoplasmic Vesicles/metabolism[MESH]
  • |Membrane Microdomains/*metabolism[MESH]

  • *{{pmid12771123}}
    *<b>[ Caveolae/raft-dependent endocytosis ]</b> J Cell Biol 2003; 161(4) ; 673-7 Nabi IR; Le PU


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    J Cell Biol

    673 4.161 2003