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The contribution of N-glycans and their processing in the endoplasmic reticulum to glycoprotein biosynthesis Trombetta ESGlycobiology 2003[Sep]; 13 (9): 77R-91RThe attachment of N-glycans to nascent glycoproteins in the endoplasmic reticulum (ER) is intimately related to glycoprotein biogenesis. Processing of N-linked oligosaccharides begins in the ER and participates in glycoprotein folding and assembly. The elucidation of N-glycan processing mechanisms in the ER is uncovering their role in glycoprotein biosynthesis.|Animals[MESH]|Carbohydrate Sequence[MESH]|Endoplasmic Reticulum/*metabolism[MESH]|Glycoproteins/*biosynthesis/chemistry/metabolism[MESH]|Glycosylation[MESH]|Humans[MESH]|Molecular Sequence Data[MESH]|Polysaccharides/*metabolism[MESH] |
