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lüll Adaptation in the corticothalamic loop: computational prospects of tuning the senses Hillenbrand U; van Hemmen JLPhilos Trans R Soc Lond B Biol Sci 2002[Dec]; 357 (1428): 1859-67The present article discusses computational hypotheses on corticothalamic feedback and modulation of cortical response properties. We have recently proposed that the two phenomena are related, hypothesizing that neuronal velocity preference in the visual cortex is altered by feedback to the lateral geniculate nucleus. We now contrast the common view that response adaptation to stimuli subserves a function of redundancy reduction with the idea that it may enhance cortical representation of objects. Our arguments lead to the concept that the corticothalamic loop is involved in reducing sensory input to behaviourally relevant aspects, a pre-attentive gating.|Adaptation, Physiological[MESH]|Animals[MESH]|Cerebral Cortex/*physiology[MESH]|Computer Simulation[MESH]|Feedback[MESH]|Geniculate Bodies/physiology[MESH]|Models, Neurological[MESH]|Nerve Net/physiology[MESH]|Neural Pathways/physiology[MESH]|Thalamus/*physiology[MESH]|Visual Cortex/physiology[MESH] |