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lüll Severe meningococcal disease in childhood Baines PB; Hart CABr J Anaesth 2003[Jan]; 90 (1): 72-83Meningococcal disease remains an important cause of illness in the UK (Commun Dis Rep CDR Suppl 1999; 9: S5), and is the commonest infective cause of death in children outwith the neonatal period. Although most common in children, adults are also affected. Meningococcal vaccines offer long-term protection only against Group C disease, which causes less than half of invasive meningococcal disease (Commun Dis Rep CDR Wkly 1998; 8: 2) in the UK.|Adult[MESH]|Blood Coagulation Disorders/microbiology[MESH]|Calcium/analysis[MESH]|Carrier State/microbiology[MESH]|Child[MESH]|Cytokines/analysis[MESH]|Endothelium, Vascular/microbiology[MESH]|Endotoxins/analysis[MESH]|Extracorporeal Membrane Oxygenation[MESH]|Heart Diseases/microbiology/physiopathology[MESH]|Hemofiltration[MESH]|Humans[MESH]|Meningococcal Infections/physiopathology/*therapy/transmission[MESH]|Nasopharynx/microbiology[MESH]|Neisseria meningitidis[MESH]|Nitric Oxide/analysis[MESH]|Prognosis[MESH]|Risk Factors[MESH]|Sepsis/microbiology[MESH]|Steroids/therapeutic use[MESH] |