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Chronic obstructive pulmonary disease * 3: Experimental animal models of pulmonary emphysema Mahadeva R; Shapiro SDThorax 2002[Oct]; 57 (10): 908-14The use of genetically manipulated mice together with traditional animal studies are steadily increasing our knowledge of the factors important in determining alveolar formation and destruction in emphysema. A review of the animal models used to study emphysema is presented.|*Disease Models, Animal[MESH]|Animals[MESH]|Gene Targeting[MESH]|Genetic Engineering[MESH]|Mice[MESH]|Mice, Mutant Strains[MESH]|Mice, Transgenic[MESH]|Mutation/genetics[MESH]|Pulmonary Disease, Chronic Obstructive/*etiology[MESH]|Pulmonary Emphysema/chemically induced/*etiology[MESH] |
