Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525

Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
  English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |   
l�ll Integrins: bidirectional, allosteric signaling machines Hynes ROCell 2002[Sep]; 110 (6): 673-87In their roles as major adhesion receptors, integrins signal across the plasma membrane in both directions. Recent structural and cell biological data suggest models for how integrins transmit signals between their extracellular ligand binding adhesion sites and their cytoplasmic domains, which link to the cytoskeleton and to signal transduction pathways. Long-range conformational changes couple these functions via allosteric equilibria.|*Signal Transduction[MESH]|Allosteric Regulation[MESH]|Animals[MESH]|Binding Sites[MESH]|Cell Adhesion[MESH]|Cell Adhesion Molecules/physiology[MESH]|Cytoplasm/physiology[MESH]|Cytoskeleton/physiology[MESH]|Evolution, Molecular[MESH]|Integrins/chemistry/*physiology[MESH]|Models, Biological[MESH]|Molecular Structure[MESH]|Protein Structure, Tertiary[MESH] |