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The relationship between the thyroid gland and the liver Malik R; Hodgson HQJM 2002[Sep]; 95 (9): 559-69Thyroxine and tri-iodothyronine are essential for normal organ growth, development and function. These hormones regulate the basal metabolic rate of all cells, including hepatocytes, and thereby modulate hepatic function; the liver in turn metabolizes the thyroid hormones and regulates their systemic endocrine effects. Thyroid dysfunction may perturb liver function, liver disease modulates thyroid hormone metabolism, and a variety of systemic diseases affect both organs. We highlight the intricate relations between the thyroid gland and the liver in health and disease.|Chronic Disease[MESH]|Humans[MESH]|Liver Diseases/complications/*metabolism[MESH]|Liver/metabolism/*physiology[MESH]|Signal Transduction[MESH]|Thyroid Diseases/complications/*metabolism[MESH]|Thyroid Gland/metabolism/*physiology[MESH]|Thyroid Hormones/metabolism[MESH] |
