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Cell polarity: posterior Par-1 prevents proteolysis Benton R; St Johnston DCurr Biol 2002[Jul]; 12 (14): R479-81The Par-1 kinase is required for anterior-posterior axis formation in Drosophila. New work has identified the posterior determinant, Oskar, as a Par-1 substrate. Phosphorylation stabilises Oskar, revealing a novel mechanism controlling its asymmetric distribution.|*Caenorhabditis elegans Proteins[MESH]|*Cell Polarity[MESH]|Animals[MESH]|Drosophila Proteins/genetics/metabolism[MESH]|Drosophila/embryology[MESH]|Hydrolysis[MESH]|Phosphorylation[MESH]|Protein Serine-Threonine Kinases/metabolism/*physiology[MESH]|RNA, Messenger/genetics[MESH] |
