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English Wikipedia
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lüll Fungal endocarditis, 1995-2000 Pierrotti LC; Baddour LMChest 2002[Jul]; 122 (1): 302-10One hundred fifty-two cases of fungal endocarditis (FE) were identified in the English-language literature between January 1, 1995, and June 30, 2000. Although the median age of patients (44 years) was relatively young, injection drug use was identified as a risk factor in only 4.1% of cases. Other factors, including underlying cardiac abnormalities (47.3%), prosthetic valves (44.6%), and central venous catheters (30.4%), were more commonly identified as predisposing conditions and reflect the changing epidemiology of the syndrome. Unfortunately, mortality remains unacceptably high, particularly for patients with Aspergillus-related FE. Novel therapies are needed to improve patient outcomes.|*Endocarditis/complications/etiology/mortality[MESH]|*Fungi/isolation & purification/pathogenicity[MESH]|*Mycoses/complications/etiology/mortality[MESH]|Adolescent[MESH]|Adult[MESH]|Aged[MESH]|Aged, 80 and over[MESH]|Antifungal Agents/therapeutic use[MESH]|Child[MESH]|Child, Preschool[MESH]|Female[MESH]|Humans[MESH]|Infant[MESH]|Infant, Newborn[MESH]|Male[MESH]|Middle Aged[MESH] |