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Maspin is a tumour suppressor that inhibits breast cancer tumour metastasis in vivo Streuli CHBreast Cancer Res 2002[]; 4 (4): 137-40Maspin is a member of the serpin family of serine proteases and functions as a tumour suppressor. A study using a new syngeneic mouse model for breast cancer suggests that maspin can inhibit metastasis in vivo.|Animals[MESH]|Breast Neoplasms/enzymology/genetics/pathology[MESH]|Cell Transformation, Neoplastic/metabolism/pathology[MESH]|Epithelial Cells/enzymology[MESH]|Female[MESH]|Genes, Tumor Suppressor[MESH]|Humans[MESH]|Mammary Neoplasms, Experimental/enzymology/genetics/pathology[MESH]|Mice[MESH]|Mice, Inbred BALB C[MESH]|Muscle, Smooth/cytology/enzymology[MESH]|Neoplasm Metastasis[MESH]|Neoplasm Proteins/genetics/*physiology[MESH]|Neoplasm Transplantation[MESH]|Proteins/genetics/*physiology[MESH]|Rats[MESH]|Recombinant Fusion Proteins/physiology[MESH]|Serpins/genetics/*physiology[MESH]|Transfection[MESH]|Transplantation, Isogeneic[MESH] |
