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lüll Mechanisms of bacterial pathogenicity Wilson JW; Schurr MJ; LeBlanc CL; Ramamurthy R; Buchanan KL; Nickerson CAPostgrad Med J 2002[Apr]; 78 (918): 216-24Pathogenic bacteria utilise a number of mechanisms to cause disease in human hosts. Bacterial pathogens express a wide range of molecules that bind host cell targets to facilitate a variety of different host responses. The molecular strategies used by bacteria to interact with the host can be unique to specific pathogens or conserved across several different species. A key to fighting bacterial disease is the identification and characterisation of all these different strategies. The availability of complete genome sequences for several bacterial pathogens coupled with bioinformatics will lead to significant advances toward this goal.|Adhesins, Bacterial/physiology[MESH]|Bacteria/genetics/immunology/*pathogenicity[MESH]|Bacterial Adhesion/physiology[MESH]|Bacterial Capsules/physiology[MESH]|Bacterial Infections/etiology[MESH]|Bacterial Toxins/chemistry/classification[MESH]|Cell Wall[MESH]|Drug Resistance, Bacterial/physiology[MESH]|Humans[MESH]|Lipopolysaccharides/immunology[MESH]|Sigma Factor/physiology[MESH]|Virulence/physiology[MESH] |