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Hereditary hemochromatosis: a common, often unrecognized, genetic disease McCarthy GM; Crowe J; McCarthy CJ; Eustace S; Kenny DCleve Clin J Med 2002[Mar]; 69 (3): 224-6, 229-30, 232-3 passimHereditary hemochromatosis in people of northern European descent is more common than many physicians realize. It causes excessive gastrointestinal absorption of iron, leading to potentially fatal iron deposition in multiple organs. Early diagnosis and phlebotomy to reduce iron stores can prevent complications and provide normal life expectancy. Genetic testing of relatives of patients with hemochromatosis is warranted in some circumstances.|Algorithms[MESH]|Diagnosis, Differential[MESH]|Genetic Counseling[MESH]|Hemochromatosis/diagnosis/*genetics/therapy[MESH]|Humans[MESH]|Liver/pathology[MESH]|Phlebotomy[MESH]|Risk Factors[MESH]|Transferrin/metabolism[MESH] |
