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Beta-blockers in left ventricular systolic dysfunction--from evidence to practice Bandyopadhyay S; O'Mahony MSAge Ageing 2002[Jan]; 31 (1): 23-8Five percent of all hospital medical admissions are patients with heart failure. The incidence is about one new case per 1000 of the general population per year, increasing to >10 per 1000 in those aged >or=85 years. Although the evidence that beta-blockers reduce mortality by about 36% when added to angiotensin-converting enzyme inhibitors is overwhelming, clinicians are still reluctant to use beta-blockers in heart failure, especially in older patients. Here, we examine the evidence for the use of beta-blockers in heart failure in older people and explore the practicalities of their use.|Adrenergic beta-Antagonists/*therapeutic use[MESH]|Aged[MESH]|Aged, 80 and over[MESH]|Angiotensin-Converting Enzyme Inhibitors/*therapeutic use[MESH]|Coronary Disease/*drug therapy[MESH]|Female[MESH]|Humans[MESH]|Male[MESH]|Ventricular Dysfunction, Left/*drug therapy[MESH] |
