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Drug-induced urticaria Cousin F; Philips K; Favier B; Bienvenu J; Nicolas JFEur J Dermatol 2001[May]; 11 (3): 181-7The occurrence of acute urticaria during treatment with drugs is a frequent event which poses two problems: 1) is the urticaria connected with the drug administration or with the underlying pathology which led to the prescription of the drug; 2) is the urticaria allergic in origin, i.e. due to specific immunity triggers, in particular IgE directed against the drug, or is the urticaria pseudo-allergic in origin, i.e. due to non-specific activation of mastocytes [1]? This question is of major importance because allergic events caused by IgE are potentially fatal while pseudo-allergic events are only rarely life-threatening. In this article we will not deal with contact urticaria where the cause is easily identifiable [2].|Acute Disease[MESH]|Angiotensin-Converting Enzyme Inhibitors/adverse effects[MESH]|Arachidonic Acid/metabolism[MESH]|Chronic Disease[MESH]|Diagnosis, Differential[MESH]|Humans[MESH]|Kinins/metabolism[MESH]|Renin-Angiotensin System/drug effects[MESH]|Terminology as Topic[MESH]|Urticaria/*chemically induced/classification/diagnosis/*metabolism/physiopathology/therapy[MESH] |
