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Congenital vascular lesions of the gastrointestinal tract: blue rubber bleb nevus and Klippel-Trenaunay syndromes Arguedas MR; Shore G; Wilcox CMSouth Med J 2001[Apr]; 94 (4): 405-10We present two cases of hemangiomatosis of the gastrointestinal tract. The first case describes a 59-year-old patient with upper gastrointestinal hemorrhage due to the blue rubber bleb nevus syndrome. The second case illustrates a 26-year-old patient with recurrent rectal bleeding due to Klippel-Trenaunay syndrome. These two syndromes are distinct disorders characterized by cavernous hemangiomas of the skin, soft-tissue, bones, and viscera. In addition, we review the available literature on the epidemiology, transmission, clinical features, associated conditions, diagnosis, and treatment of these two disorders.|Adult[MESH]|Endoscopy, Digestive System[MESH]|Gastrointestinal Hemorrhage/etiology[MESH]|Gastrointestinal Neoplasms/*congenital/*diagnosis/genetics/therapy[MESH]|Genes, Dominant[MESH]|Hemangioma, Capillary/*congenital/*diagnosis/genetics/therapy[MESH]|Humans[MESH]|Klippel-Trenaunay-Weber Syndrome/*congenital/*diagnosis/genetics/therapy[MESH]|Male[MESH]|Middle Aged[MESH]|Nevus, Blue/*congenital/*diagnosis/genetics/therapy[MESH]|Recurrence[MESH]|Sclerotherapy/methods[MESH]|Syndrome[MESH]|Tomography, X-Ray Computed[MESH] |
