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lüll Making decisions through Myc Nasi S; Ciarapica R; Jucker R; Rosati J; Soucek LFEBS Lett 2001[Feb]; 490 (3): 153-62c-Myc is a transcriptional regulator involved in carcinogenesis through its role in growth control and cell cycle progression. Here we attempt to relate its role in stimulating the G1-S transition to the ability to affect functioning of key cell cycle regulators, and we focus on how its property of modulating transcription of a wide range of target genes could explain its capacity to affect multiple pathways leading to proliferation, apoptosis, growth, and transformation.|*Cell Cycle/genetics[MESH]|Animals[MESH]|Cell Cycle Proteins/metabolism[MESH]|Cell Division/genetics[MESH]|Cyclin-Dependent Kinases/metabolism[MESH]|Cyclins/metabolism[MESH]|G1 Phase/genetics[MESH]|Gene Expression Regulation[MESH]|Proto-Oncogene Proteins c-myc/genetics/*metabolism[MESH]|S Phase/genetics[MESH]|Transcription, Genetic[MESH] |