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lüll Antigen traffic pathways in dendritic cells Watts C; Amigorena STraffic 2000[Apr]; 1 (4): 312-7Dendritic cells (DC) are now believed to be the principal initiators of T cell-mediated immune responses. Their location in body tissues, migratory behaviour in response to inflammatory stimuli, endocytic properties, expression of MHC molecules and key T cell stimulatory molecules and many other attributes place these remarkable cells in a unique and influential position in the immune system. Progress in DC culture methods has recently allowed in-depth studies on the cell biological features that enable them to fulfill their crucial role in the immune response.|*Biological Transport[MESH]|Animals[MESH]|Antigen Presentation[MESH]|Antigens/metabolism[MESH]|Cell Adhesion[MESH]|Cell Culture Techniques[MESH]|Cell Movement[MESH]|Dendritic Cells/*cytology/*metabolism[MESH]|Endocytosis[MESH]|Histocompatibility Antigens Class I/metabolism[MESH]|Humans[MESH]|Models, Biological[MESH] |