Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Regulation of Ets function by protein - protein interactions Li R; Pei H; Watson DKOncogene 2000[Dec]; 19 (55): 6514-23Ets proteins are a family of transcription factors that share an 85 amino acid conserved DNA binding domain, the ETS domain. Over 25 mammalian Ets family members control important biological processes, including cellular proliferation, differentiation, lymphocyte development and activation, transformation and apoptosis by recognizing the GGA core motif in the promoter or enhancer of their target genes. Protein - protein interactions regulates DNA binding, subcellular localization, target gene selection and transcriptional activity of Ets proteins. Combinatorial control is a characteristic property of Ets family members, involving interaction between Ets and other key transcriptional factors such as AP-1, NFkappaB and Pax family members. Specific domains of Ets proteins interact with many protein motifs such as bHLH, bZipper and Paired domain. Such interactions coordinate cellular processes in response to diverse signals including cytokines, growth factors, antigen and cellular stresses.|*Multigene Family[MESH]|Amino Acid Motifs[MESH]|Animals[MESH]|Basic Helix-Loop-Helix Transcription Factors[MESH]|Binding Sites[MESH]|Consensus Sequence[MESH]|DNA-Binding Proteins/chemistry/genetics/metabolism/*physiology[MESH]|DNA/metabolism[MESH]|Dimerization[MESH]|Gene Expression Regulation/genetics/*physiology[MESH]|Humans[MESH]|Macromolecular Substances[MESH]|Mammals/genetics[MESH]|Models, Genetic[MESH]|NF-kappa B/metabolism[MESH]|Nuclear Proteins/physiology[MESH]|Protein Binding/*physiology[MESH]|Protein Structure, Tertiary[MESH]|Proto-Oncogene Proteins c-ets[MESH]|Proto-Oncogene Proteins/chemistry/genetics/physiology[MESH]|Retinoblastoma Protein/physiology[MESH]|Trans-Activators/physiology[MESH]|Transcription Factor AP-1/metabolism[MESH]|Transcription Factors/chemistry/genetics/metabolism/*physiology[MESH]|Transcription, Genetic/genetics/physiology[MESH] |
