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lüll Vertebrate development: the fast track to nodal signalling Stemple DLCurr Biol 2000[Nov]; 10 (22): R843-6The transcription factors Fast-1 and Mixer are important terminal components of Smad2-mediated TGF-beta signal transduction. Recent studies demonstrate that Fast-1 and Mixer play critical roles in the formation of endoderm and dorsal mesoderm in zebrafish.|*Xenopus Proteins[MESH]|*Zebrafish Proteins[MESH]|Animals[MESH]|DNA-Binding Proteins/genetics/metabolism/*physiology[MESH]|Forkhead Transcription Factors[MESH]|GPI-Linked Proteins[MESH]|Homeodomain Proteins/genetics/metabolism/*physiology[MESH]|Intercellular Signaling Peptides and Proteins[MESH]|Membrane Proteins[MESH]|Mutagenesis[MESH]|Nodal Protein[MESH]|Signal Transduction/*physiology[MESH]|Transcription Factors/genetics/metabolism/*physiology[MESH]|Transforming Growth Factor beta/*metabolism/physiology[MESH]|Zebrafish/*embryology[MESH] |