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Antiviral therapy for enteroviruses and rhinoviruses Rotbart HAAntivir Chem Chemother 2000[Jul]; 11 (4): 261-71The picornaviruses are a diverse group of viral pathogens that together comprise the most common causes of infection of humans in the developed world. Within the picornavirus family are three well-known groups of human pathogens--the rhinoviruses, the enteroviruses (including polioviruses, coxsackieviruses and echoviruses) and the hepatoviruses (including hepatitis A virus). This article will focus on the rhinoviruses and enteroviruses, agents for which substantial effort has been expended, and recent successes reported, toward the development of safe and effective antiviral therapy.|*Viral Proteins[MESH]|3C Viral Proteases[MESH]|Animals[MESH]|Antiviral Agents/*therapeutic use[MESH]|Benzimidazoles/therapeutic use[MESH]|Capsid/antagonists & inhibitors[MESH]|Cell Line[MESH]|Common Cold/drug therapy[MESH]|Cysteine Endopeptidases/chemistry[MESH]|Drug Resistance, Microbial[MESH]|Enterovirus Infections/drug therapy/virology[MESH]|Enterovirus/*drug effects[MESH]|Humans[MESH]|Immunoglobulins, Intravenous/therapeutic use[MESH]|Interferons/therapeutic use[MESH]|Molecular Structure[MESH]|Oximes[MESH]|Picornaviridae Infections/*drug therapy/virology[MESH]|Rhinovirus/*drug effects[MESH]|Sulfonamides[MESH] |
