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English Wikipedia
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Primary biliary cirrhosis: new perspectives in diagnosis and treatment Prince MI; Jones DEPostgrad Med J 2000[Apr]; 76 (894): 199-206Primary biliary cirrhosis (PBC) is a chronic autoimmune disease characterised by cholestatic liver function tests, antimitochondrial antibodies, and abnormal liver histology. Early descriptions of a rare rapidly progressive disease no longer reflect the more indolent progress often seen today. Many patients have significant long term morbidity through symptoms such as fatigue and itch with a minority progressing to liver failure and need for transplantation. The current data on the diagnosis, clinical progression, and treatment of PBC are reviewed.|Humans[MESH]|Liver Cirrhosis, Biliary/complications/*diagnosis/*therapy[MESH]|Liver Transplantation[MESH]|Prognosis[MESH]|Pruritus/etiology[MESH] |
