suck pdf from google scholar
PDF vom PMID10679804 :   free
suck pdf from library genesis
English Wikipedia

Nephropedia Template TP (

Twit Text


  • DeepDyve
  • Pubget Overpricing


  • lüll
  • Ticlopidine-induced aplastic anemia: development of chromosomal abnormalities and response to immunosuppressive therapy
  • Pullarkat VA; Rho H; Murata-Collins JL; Liebman HA
  • Am J Hematol 2000[Mar]; 63 (3): 141-4
  • Severe aplastic anemia is a well-recognized complication of ticlopidine therapy that carries a high mortality. Therapy with colony-stimulating factors or corticosteroids has been largely ineffective in this disorder. We report a case of ticlopidine-induced aplastic anemia that was successfully treated with cyclosporine and high-dose dexamethasone. The patient rapidly responded to immunosuppressive therapy and had a normal hemogram after cessation of immunosuppression. On long-term follow-up, the patient developed a progressive macrocytic anemia. Repeat bone marrow evaluation demonstrated myelodysplasia with erythroid hypoplasia. An associated chromosomal abnormality consisting of a t(3;16) (q21; p13.3) translocation was detected. This is the first report of a chromosomal abnormality associated with ticlopidine induced marrow aplastic anemia.
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Anemia, Aplastic/*chemically induced/*drug therapy/genetics[MESH]
  • |Bone Marrow/*drug effects[MESH]
  • |Chromosome Aberrations/*chemically induced/*drug therapy[MESH]
  • |Chromosome Disorders[MESH]
  • |Cyclosporine/therapeutic use[MESH]
  • |Dexamethasone/therapeutic use[MESH]
  • |Fibrinolytic Agents/adverse effects[MESH]
  • |Humans[MESH]
  • |Immunosuppressive Agents/*therapeutic use[MESH]
  • |Male[MESH]
  • |Platelet Aggregation Inhibitors/adverse effects[MESH]
  • |Ticlopidine/*adverse effects[MESH]
  • |Treatment Outcome[MESH]





  • *{{pmid10679804}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=10679804 Ticlopidine-induced aplastic anemia: development of chromosomal abnormalities and response to immunosuppressive therapy ]</b> Am J Hematol 2000; 63(3) ; 141-4 Pullarkat VA; Rho H; Murata-Collins JL; Liebman HA

        *10679804*

    Nephropedia PMID record

    Deutsche Wikipedia - im Artikel

    Hier den unten stehenden Textblock hineinkopieren

    Am J Hematol

    141 3.63 2000