Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Structure and mechanism of proton-translocating transhydrogenase Jackson JB; Peake SJ; White SAFEBS Lett 1999[Dec]; 464 (1-2): 1-8Recent developments have led to advances in our understanding of the structure and mechanism of action of proton-translocating (or AB) transhydrogenase. There is (a) a high-resolution crystal structure, and an NMR structure, of the NADP(H)-binding component (dIII), (b) a homology-based model of the NAD(H)-binding component (dI) and (c) an emerging consensus on the position of the transmembrane helices (in dII). The crystal structure of dIII, in particular, provides new insights into the mechanism by which the energy released in proton translocation across the membrane is coupled to changes in the binding affinities of NADP(+) and NADPH that drive the chemical reaction.|Alanine Dehydrogenase[MESH]|Amino Acid Oxidoreductases/chemistry[MESH]|Bacterial Proteins/chemistry[MESH]|Binding Sites[MESH]|Crystallography, X-Ray[MESH]|Humans[MESH]|Models, Chemical[MESH]|Models, Molecular[MESH]|NADP Transhydrogenases/*chemistry/*metabolism[MESH]|Protein Binding[MESH]|Protein Structure, Tertiary[MESH]|Recombinant Proteins/chemistry[MESH] |