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Nuclear magnetic resonance monitoring of treatment and prediction of outcome in multiple sclerosis Miller DH; Thompson AJPhilos Trans R Soc Lond B Biol Sci 1999[Oct]; 354 (1390): 1687-95Magnetic resonance (MR) techniques provide an objective, sensitive and quantitative assessment of the evolving pathology in multiple sclerosis. There is an increasing definition of the pathological specificity of newer techniques, and more robust correlations with clinical evolution are emerging. As the pathophysiological basis of in vivo nuclear MR signal abnormalities is further elucidated, it is likely that the importance of MR as a tool to monitor new therapies will increase.|*Magnetic Resonance Imaging[MESH]|Clinical Trials as Topic[MESH]|Humans[MESH]|Multiple Sclerosis/*diagnosis/*therapy[MESH]|Pilot Projects[MESH]|Prognosis[MESH]|Research Design[MESH] |
