Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Behcet s syndrome: a multidisciplinary approach to clinical care Whallett AJ; Thurairajan G; Hamburger J; Palmer RG; Murray PIQJM 1999[Dec]; 92 (12): 727-40Behcet's syndrome is a multisystem disorder characterized by recurrent orogenital ulceration and an occlusive vasculitis. Histologically, there is a combination of a perivascular lymphocytic infiltration with endothelial cell damage coupled with a pro-thrombotic tendency. We present a multidisciplinary approach to the management of Behcet's syndrome, and compare our findings with other published studies. Over a nine-year period, 50 patients with Behcet's syndrome were followed in a multidisciplinary combined clinic. Patients were assessed by an ophthalmologist, a rheumatologist and a specialist in oral medicine. Data on disease activity and damage were collected using a standardized proforma for each specialty. Mean age of onset was 30 years; 56% were male. Recurrent oral ulceration was the commonest manifestation and the presenting feature in 76%. The commonest second systems involved were genital mucosae and eyes. We found a larger proportion of patients with ophthalmic (80%) and central nervous system (14%) manifestations compared with many other studies. There was an association between central nervous system and thrombotic events (p<0.001). Our multidisciplinary approach allowed us to keep each system involved in Behcet's syndrome under careful review. The development of recurrent sight-threatening eye disease was unpredictable and occurred despite aggressive immunosuppression.|Adolescent[MESH]|Adult[MESH]|Aged[MESH]|Behcet Syndrome/complications/*therapy[MESH]|Disease Progression[MESH]|Eye Diseases/etiology/therapy[MESH]|Female[MESH]|Humans[MESH]|Longitudinal Studies[MESH]|Male[MESH]|Middle Aged[MESH]|Nervous System Diseases/etiology/therapy[MESH]|Oral Ulcer/etiology/therapy[MESH]|Patient Care Team[MESH]|Skin Diseases/etiology/therapy[MESH]|Vascular Diseases/etiology/therapy[MESH] |