Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Anticancer drug design based on plant-derived natural products Lee KHJ Biomed Sci 1999[Jul]; 6 (4): 236-50This review article focuses on recent research in my laboratory on various classes of compounds that possess potent antitumor activity. These compounds were obtained by bioactivity- and mechanism of action-directed isolation and characterization coupled with rational drug design-based modification and analog synthesis. Structural modification, structure-activity relationship, and mechanism of action studies will be discussed.|*Topoisomerase II Inhibitors[MESH]|Animals[MESH]|Antineoplastic Agents/*chemistry/*pharmacology[MESH]|Camptothecin/analogs & derivatives[MESH]|Colchicine/analogs & derivatives[MESH]|Drug Design[MESH]|Enzyme Inhibitors/*chemistry/pharmacology[MESH]|Etoposide/analogs & derivatives/metabolism[MESH]|Flavonoids/chemistry[MESH]|Humans[MESH]|Plants/*chemistry[MESH]|Topoisomerase I Inhibitors[MESH]|Tubulin Modulators[MESH] |