Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Prevention of activation of blood coagulation during acute coronary ischemic syndromes: beyond aspirin and heparin Bates SM; Weitz JICardiovasc Res 1999[Feb]; 41 (2): 418-32Many of the acute coronary ischemic syndromes are triggered by spontaneous or mechanical disruption of atherosclerotic plaques with resultant activation of platelets and coagulation. Given the central role of platelets and thrombin in arterial thrombosis, current strategies for its prevention and treatment focus on both inhibition of platelet aggregation and control of thrombin generation and activity. Although aspirin and unfractionated heparin are the cornerstones of current treatment strategies, both have limitations. This review will describe these limitations and discuss new antithrombotic agents developed for use in acute coronary ischemic syndromes and as adjuncts for percutaneous coronary revascularization procedures.|Anticoagulants/*therapeutic use[MESH]|Aspirin/therapeutic use[MESH]|Fibrinolytic Agents/therapeutic use[MESH]|Heparin/therapeutic use[MESH]|Humans[MESH]|Myocardial Ischemia/*drug therapy[MESH]|Platelet Aggregation Inhibitors/therapeutic use[MESH]|Thrombin/antagonists & inhibitors[MESH] |