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lüll The evolution of antibiotic therapy for neutropenic patients Bodey GPClin Cancer Res 1997[Dec]; 3 (12 Pt 2): 2660-5Considerable progress has been made in the treatment of infections in neutropenic patients during the past three decades. A major contribution to this progress has been the discovery of effective new therapies and their prompt administration. Unfortunately, successful therapy of each important pathogen has resulted in the emergence of new pathogens, usually with unique patterns of antibiotic susceptibility. Unfortunately, antibiotic resistance has become an increasing threat in recent years, raising the possibility of infections that will be difficult to eradicate. Fortunately, there are new classes of antimicrobials that hold promise for therapeutic success in the future.|Anti-Bacterial Agents/*therapeutic use[MESH]|Antineoplastic Combined Chemotherapy Protocols/*adverse effects[MESH]|Bacterial Infections/*drug therapy/etiology/prevention & control[MESH]|Controlled Clinical Trials as Topic[MESH]|Humans[MESH]|Leukemia/*drug therapy[MESH]|Neutropenia/*complications[MESH] |