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alpha1 Antitrypsin and its deficiency A1AT

Nr.	Year OPEN	Title	rate good	rate bad	no link	Citation
1	1984	alpha 1-Antitrypsin deficiency.	+	-	nl	South Med J 77(4):479-83 (1984)
2	1996	Systemic necrotizing vasculitides in severe alpha1-antitrypsin deficiency.	+	-	nl	QJM 89(8):599-611 (1996)
3	2010	Intravenous alpha-1 antitrypsin augmentation therapy: systematic review.	+	-	nl	Dan Med Bull 57(9):A4175 (2010) Gotzsche PC
4	2007	Heterozygous alpha-I antitrypsin deficiency as a co-factor in the development of chronic liver disease: a review.	+	-	nl	Neth J Med 65(5):160-6 (2007) Kok KF
5	2007	Primary care diagnosis of alpha-1 antitrypsin deficiency: issues and opportunities.	+	-	nl	Cleve Clin J Med 74(12):869-74 (2007) Stoller JK
6	2009	Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency.	+	-	nl	Biologics 3():193-204 (2009) Petrache I
7	1999	Cefoperazone prevents the inactivation of alpha(1)-antitrypsin by activated neutrophils.	+	-	nl	Antimicrob Agents Chemother 43(9):2307-10 (1999)
8	2006	Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management.	+	-	nl	Int J Chron Obstruct Pulmon Dis 1(2):151-60 (2006) Stolk J
9	1999	Alpha 1-antitrypsin deficiency and related liver disease.	+	-	nl	Saudi J Gastroenterol 5(1):1-8 (1999)
10	2003	American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency.	+	-	nl	Am J Respir Crit Care Med 168(7):818-900 (2003)
11	1976	Alpha 1-antitrypsin deficiency and infantile liver disease.	+	-	nl	Arch Dis Child 51(8):584-8 (1976)
12	2006	The role of autophagy in alpha-1-antitrypsin deficiency: a specific cellular response in genetic diseases associated with aggregation-prone proteins.	+	-	nl	Autophagy 2(4):258-63 (2006) Perlmutter DH
13	2009	Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in alpha-1-antitrypsin deficiency.	+	-	nl	Cell Death Differ 16(1):39-45 (2009) Perlmutter DH
14	2005	Mortality in individuals with severe deficiency of alpha1-antitrypsin: findings from the National Heart, Lung, and Blood Institute Registry.	+	-	nl	Chest 127(4):1196-204 (2005) Stoller JK
15	2004	Alpha1-antitrypsin deficiency: more than a protease imbalance?	+	-	nl	Chest 125(5):1607-9 (2004) Wewers MD
16	2003	Augmentation therapy with alpha1-antitrypsin: patterns of use and adverse events.	+	-	nl	Chest 123(5):1425-34 (2003) Stoller JK
17	1996	Pathogenesis and pathology of liver disease associated with alpha 1-antitrypsin deficiency.	+	-	nl	Chest 110(6 Suppl):251S-255S (1996)
18	1996	Alpha 1-antitrypsin deficiency. A conformational disease.	+	-	nl	Chest 110(6 Suppl):243S-247S (1996)
19	1996	A 30-year perspective on alpha 1-antitrypsin deficiency.	+	-	nl	Chest 110(6 Suppl):237S-242S (1996)
20	2004	Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.	+	-	nl	Eur J Hum Genet 12(3):167-72 (2004) Crowther DC
21	2007	Revisiting alpha1-antitrypsin therapy in cystic fibrosis: can it still offer promise?	+	-	nl	Eur Respir J 29(2):229-30 (2007) Brennan S
22	2005	alpha1-Antitrypsin deficiency and lung disease: risk modification by occupational and environmental inhalants.	+	-	nl	Eur Respir J 26(5):909-17 (2005) Senn O
23	1990	Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy.	+	-	nl	J Clin Invest 85(5):1343-52 (1990)
24	1986	alpha 1-Antitrypsin: molecular pathology, leukocytes, and tissue damage.	+	-	nl	J Clin Invest 78(6):1427-31 (1986)
25	2008	Hereditary alpha-1-antitrypsin deficiency and its clinical consequences.	+	-	nl	Orphanet J Rare Dis 3():16 (2008) Fregonese L
26	2008	Alpha-1 antitrypsin: now available, but do we need it?	+	-	nl	Swiss Med Wkly 138(13-14):191-6 (2008) Russi EW
27	2004	Alpha1-antitrypsin deficiency. 7: Computed tomographic imaging in alpha1-antitrypsin deficiency.	+	-	nl	Thorax 59(11):986-91 (2004) Shaker SB
28	2004	alpha1-Antitrypsin deficiency . 6: new and emerging treatments for alpha1-antitrypsin deficiency.	+	-	nl	Thorax 59(10):904-9 (2004) Sandhaus RA
29	2004	alpha1-Antitrypsin deficiency . 5: intravenous augmentation therapy: current understanding.	+	-	nl	Thorax 59(8):708-12 (2004) Stoller JK
30	2004	Alpha1-antitrypsin deficiency. 4: Molecular pathophysiology.	+	-	nl	Thorax 59(6):529-35 (2004) Lomas DA
31	2004	Alpha 1-antitrypsin deficiency. 3: Clinical manifestations and natural history.	+	-	nl	Thorax 59(5):441-5 (2004) Needham M
32	2004	Alpha1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema risk.	+	-	nl	Thorax 59(3):259-64 (2004) DeMeo DL
33	1987	Association of alpha 1-antitrypsin deficiency with lung and liver diseases.	+	-	nl	West J Med 147(1):48-53 (1987)
34	2007	Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review.	+	-	nl	Hepatology 45(5):1313-23 (2007) Perlmutter DH
35	1996	Molecular pathogenesis of liver disease in alpha1-antitrypsin deficiency.	+	-	nl	Hepatology 24(6):1504-16 (1996)
36	2003	Key current clinical issues in alpha-1 antitrypsin deficiency.	+	-	nl	Respir Care 48(12):1216-21; discussion 1221-4 (2003)
37	2003	Alpha-1 antitrypsin deficiency: an under-recognized but important issue for respiratory therapists.	+	-	nl	Respir Care 48(11):1022-4 (2003)
38	2009	Clinical characteristics of subjects with symptoms of alpha1-antitrypsin deficiency older than 60 years.	+	-	nl	Chest 135(3):600-8 (2009)
39	2009	Alpha1-antitrypsin deficiency: lessons from longevity.	+	-	nl	Chest 135(3):591-2 (2009) Eden E
40	2008	Screening and familial testing of patients for alpha 1-antitrypsin deficiency.	+	-	nl	Chest 133(4):981-8 (2008)
41	2010	Intracellular processing of alpha1-antitrypsin.	+	-	nl	Proc Am Thorac Soc 7(6):376-80 (2010)
42	2010	Lung disease associated with alpha1-antitrypsin deficiency.	+	-	nl	Proc Am Thorac Soc 7(6):381-6 (2010)
43	2004	Alpha 1-antitrypsin: more than just deficiency.	+	-	nl	Thorax 59(5):363-4 (2004)
44	2006	Validation of computed tomographic lung densitometry for monitoring emphysema in alpha1-antitrypsin deficiency.	+	-	nl	Thorax 61(6):485-90 (2006)
45	2006	The selective advantage of alpha1-antitrypsin deficiency.	+	-	nl	Am J Respir Crit Care Med 173(10):1072-7 (2006)
46	2004	Alpha-1 antitrypsin deficiency with severe pulmonary emphysema.	+	-	nl	Intern Med 43(3):223-6 (2004)
47	2009	Mechanisms of emphysema in alpha1-antitrypsin deficiency: molecular and cellular insights.	+	-	nl	Eur Respir J 34(2):475-88 (2009)
48	2003	Alpha-1 antitrypsin deficiency is not a rare disease but a disease that is rarely diagnosed.	+	-	nl	Environ Health Perspect 111(16):1851-4 (2003)

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