| Nr. | Year OPEN | Title | users say> | rate good | rate bad | no link | Citation |
UbiquitinPupylationE3 ubiquitin ligaseFbw7 Sel10 hCdc4 AgoNervous System (Pathology)Nervous system (Neurodegeneration)SynapseWnt beta Catenin TCFCell cylce (BASKET)CRL4Cdt2AlcoholProteasomeBortezomibTRAFNFKBLUBAC linear ubiquitin chain assembly complexCblSMURF2SMURF1HDM2BCA2SCF (betaTRCP)XRNF185TRIM32RNF5TRAF3DUBTRAF2TRAF6| 1 | 2010 | Pupylation versus ubiquitylation: tagging for proteasome-dependent degradation. | 
| + | - | nl | Cell Microbiol 12(4):424-31 (2010) |
| 2 | 2009 | How microbes utilize host ubiquitination. | 
| + | - | nl | Cell Microbiol 11(10):1425-34 (2009) |
| 3 | 2007 | The enzymes in ubiquitin-like post-translational modifications. | 
| + | - | nl | Biosci Trends 1(1):16-25 (2007) |
| 4 | 2008 | The ubiquitin system, disease, and drug discovery. | 
| + | - | nl | BMC Biochem 9 Suppl 1(-):S7 (2008) |
| 5 | 2008 | Deubiquitylating enzymes and disease. | 
| + | - | nl | BMC Biochem 9 Suppl 1(-):S3 (2008) |
| 6 | 2007 | Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes. | 
| + | - | nl | BMC Biochem 8 Suppl 1(-):S9 (2007) |
| 7 | 2007 | Roles and potential therapeutic targets of the ubiquitin proteasome system in muscle wasting. | 
| + | - | nl | BMC Biochem 8 Suppl 1(-):S7 (2007) |
| 8 | 2007 | Ubiquitin domain proteins in disease. | 
| + | - | nl | BMC Biochem 8 Suppl 1(-):S1 (2007) |
| 9 | 2005 | E3 ubiquitin ligases as regulators of membrane protein trafficking and degradation. | 
| + | - | nl | Traffic 6(6):429-41 (2005) |
| 10 | 2008 | Structures of proteases for ubiqutin and ubiquitin-like modifiers. | 
| + | - | nl | BMB Rep 41(6):435-43 (2008) |
| 11 | 2006 | Role of ubiquitylation in cellular membrane transport. | 
| + | - | nl | Physiol Rev 86(2):669-707 (2006) |
| 12 | 2002 | The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. | 
| + | - | nl | Physiol Rev 82(2):373-428 (2002) |
| 13 | 1997 | Pathways of ubiquitin conjugation. | 
| + | - | nl | FASEB J 11(14):1257-68 (1997) |
| 14 | 1997 | Regulation of ubiquitin-dependent processes by deubiquitinating enzymes. | 
| + | - | nl | FASEB J 11(14):1245-56 (1997) |
| 15 | 1997 | Ubiquitin-dependent internalization and down-regulation of plasma membrane proteins. | 
| + | - | nl | FASEB J 11(14):1215-26 (1997) |
| 16 | 2007 | Decoding ubiquitin sorting signals for clathrin-dependent endocytosis by CLASPs. | 
| + | - | nl | J Cell Sci 120(Pt 4):543-53 (2007) |
| 17 | 2004 | Ubiquitin-protein ligases. | 
| + | - | nl | J Cell Sci 117(Pt 22):5191-4 (2004) |
| 18 | 2005 | Ubiquitylation and cell signaling. | 
| + | - | nl | EMBO J 24(19):3353-9 (2005) |
| 19 | 1998 | The ubiquitin-proteasome pathway: on protein death and cell life. | 
| + | - | nl | EMBO J 17(24):7151-60 (1998) |
| 20 | 2006 | The ubiquitin-proteasome system in cardiac physiology and pathology. | 
| + | - | nl | Am J Physiol Heart Circ Physiol 291(1):H1-H19 (2006) |
| 21 | 2006 | Narrative review: protein degradation and human diseases: the ubiquitin connection. | 
| + | - | nl | Ann Intern Med 145(9):676-84 (2006) |
| 22 | 2008 | Protein partners of deubiquitinating enzymes. | 
| + | - | nl | Biochem J 414(2):161-75 (2008) |
| 23 | 2006 | Ubiquitin-binding domains. | 
| + | - | nl | Biochem J 399(3):361-72 (2006) |
| 24 | 2005 | c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses. | 
| + | - | nl | Biochem J 391(Pt 2):153-66 (2005) |
| 25 | 2004 | Getting into position: the catalytic mechanisms of protein ubiquitylation. | 
| + | - | nl | Biochem J 379(Pt 3):513-25 (2004) |
| 26 | 2005 | The ubiquitin system for protein degradation and some of its roles in the control of the cell division cycle. | 
| + | - | nl | Cell Death Differ 12(9):1191-7 (2005) |
| 27 | 2005 | Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting. | 
| + | - | nl | Cell Death Differ 12(9):1178-90 (2005) |
| 28 | 2005 | Discovery of the ubiquitin proteasome system and its involvement in apoptosis. | 
| + | - | nl | Cell Death Differ 12(9):1155-7 (2005) |
| 29 | 1999 | The role of the ubiquitin-proteasome pathway in apoptosis. | 
| + | - | nl | Cell Death Differ 6(4):303-13 (1999) |
| 30 | 2008 | Cullin-RING ubiquitin ligases: global regulation and activation cycles. | 
| + | - | nl | Cell Div 3(-):7 (2008) |
| 31 | 2006 | Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting. | 
| + | - | nl | Exp Biol Med (Maywood) 231(7):1197-211 (2006) |
| 32 | 2001 | Ubiquitin-mediated degradation of cellular proteins: why destruction is essential for construction, and how it got from the test tube to the patient's bed. | 
| + | - | nl | Isr Med Assoc J 3(5):319-27 (2001) |
| 33 | 2006 | Protein degradation by the ubiquitin-proteasome pathway in normal and disease states. | 
| + | - | nl | J Am Soc Nephrol 17(7):1807-19 (2006) |
| 34 | 2003 | Non-traditional functions of ubiquitin and ubiquitin-binding proteins. | 
| + | - | nl | J Biol Chem 278(38):35857-60 (2003) |
| 35 | 2008 | The HECT family of E3 ubiquitin ligases: multiple players in cancer development. | 
| + | - | nl | Cancer Cell 14(1):10-21 (2008) |
| 36 | 2005 | A genomic and functional inventory of deubiquitinating enzymes. | 
| + | - | nl | Cell 123(5):773-86 (2005) |
| 37 | 2004 | Back to the future with ubiquitin. | 
| + | - | nl | Cell 116(2):181-90 (2004) |
| 38 | 2000 | RING finger proteins: mediators of ubiquitin ligase activity. | 
| + | - | nl | Cell 102(5):549-52 (2000) |
| 39 | 2007 | Structural insights into early events in the conjugation of ubiquitin and ubiquitin-like proteins. | 
| + | - | nl | Mol Cell 27(2):174-5 (2007) |
| 40 | 2003 | Conjugation and deconjugation of ubiquitin regulating the destiny of proteins. | 
| + | - | nl | Exp Mol Med 35(1):1-7 (2003) |
| 41 | 2010 | Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets. | 
| + | - | nl | Cancer Biol Ther 10(8):737-47 (2010) |
| 42 | 2003 | Targeting E3 ubiquitin ligases for cancer therapy. | 
| + | - | nl | Cancer Biol Ther 2(6):623-9 (2003) |
| 43 | 2005 | Tumor suppressor activities of the Fbw7 E3 ubiquitin ligase receptor. | 
| + | - | nl | Cancer Biol Ther 4(5):506-8 (2005) |
| 44 | 2009 | The ubiquitin proteasome system in neuropathology. | 
| + | - | nl | Acta Neuropathol 118(3):329-47 (2009) |
| 45 | 2010 | Structural assembly of cullin-RING ubiquitin ligase complexes. | 
| + | - | nl | Curr Opin Struct Biol 20(6):714-21 (2010) |
| 46 | 2011 | Structural regulation of cullin-RING ubiquitin ligase complexes. | 
| + | - | nl | Curr Opin Struct Biol 21(2):257-64 (2011) |
| 47 | 2007 | Taking it step by step: mechanistic insights from structural studies of ubiquitin/ubiquitin-like protein modification pathways. | 
| + | - | nl | Curr Opin Struct Biol 17(6):726-35 (2007) |
| 48 | 2008 | Ubiquitin, proteasomes and proteolytic mechanisms activated by kidney disease. | 
| + | - | nl | Biochim Biophys Acta 1782(12):795-9 (2008) |
| 49 | 2008 | The ubiquitin-proteasome system in spongiform degenerative disorders. | 
| + | - | nl | Biochim Biophys Acta 1782(12):700-12 (2008) |
| 50 | 2008 | Modulation of growth hormone receptor abundance and function: roles for the ubiquitin-proteasome system. | 
| + | - | nl | Biochim Biophys Acta 1782(12):785-94 (2008) |
| 51 | 2008 | Roles of ubiquitination at the synapse. | 
| + | - | nl | Biochim Biophys Acta 1779(8):495-506 (2008) |
| 52 | 2010 | The various roles of ubiquitin in Wnt pathway regulation. | 
| + | - | nl | Cell Cycle 9(18):3700-9 (2010) |
| 53 | 2011 | CRL4Cdt2: master coordinator of cell cycle progression and genome stability. | 
| + | - | nl | Cell Cycle 10(2):241-9 (2011) |
| 54 | 2009 | Nuclear effects of ethanol-induced proteasome inhibition in liver cells. | 
| + | - | nl | World J Gastroenterol 15(10):1163-7 (2009) |
| 55 | 2005 | Ubiquitylation of ion channels. | 
| + | - | nl | Physiology (Bethesda) 20(-):398-407 (2005) |
| 56 | 2007 | Ubiquitin and ubiquitin-like proteins in protein regulation. | 
| + | - | nl | Circ Res 100(9):1276-91 (2007) |
| 57 | 2010 | Ubiquitin, a novel paracrine messenger of cardiac cell survival. | 
| + | - | nl | Cardiovasc Res 86(1):1-3 (2010) Li D |
| 58 | 2009 | Role of non-degradative ubiquitination in interleukin-1 and toll-like receptor signaling. | 
| + | - | nl | J Biol Chem 284(13):8211-5 (2009) |
| 59 | 2008 | Polyubiquitin chains: functions, structures, and mechanisms. | 
| + | - | nl | Cell Mol Life Sci 65(15):2397-406 (2008) |
| 60 | 2009 | Ubiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradation. | 
| + | - | nl | Cell Mol Life Sci 66(17):2819-33 (2009) |
| 61 | 2011 | Regulation of cell fate determination by Skp1-Cullin1-F-box (SCF) E3 ubiquitin ligases. | 
| + | - | nl | Int J Dev Biol 55(3):249-60 (2011) |
| 62 | 2009 | Linear polyubiquitination: a new regulator of NF-kappaB activation. | 
| + | - | nl | EMBO Rep 10(7):706-13 (2009) |
| 63 | 2005 | The ubiquitin signal: assembly, recognition and termination. Symposium on ubiquitin and signaling. | 
| + | - | nl | EMBO Rep 6(9):815-20 (2005) |
| 64 | 2010 | The family of ubiquitin-conjugating enzymes (E2s): deciding between life and death of proteins. | 
| + | - | nl | FASEB J 24(4):981-93 (2010) |
| 65 | 2010 | Roles of E3 ubiquitin ligases in cell adhesion and migration. | 
| + | - | nl | Cell Adh Migr 4(1):10-8 (2010) |
| 66 | 2009 | Lysine 63 polyubiquitination in immunotherapy and in cancer-promoting inflammation. | 
| + | - | nl | Clin Cancer Res 15(22):6751-7 (2009) |
| 67 | 2011 | E2s: structurally economical and functionally replete. | 
| + | - | nl | Biochem J 433(1):31-42 (2011) |
| 68 | 2007 | Deubiquitinating enzymes as novel anticancer targets. | 
| + | - | nl | Future Oncol 3(2):191-9 (2007) |
| 69 | 2007 | Regulation of receptors and transporters by ubiquitination: new insights into surprisingly similar mechanisms. | 
| + | - | nl | Mol Interv 7(3):157-67 (2007) |
| 70 | 2009 | Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways. | 
| + | - | nl | Nat Rev Mol Cell Biol 10(5):319-31 (2009) |
| 71 | 2008 | Diversity of degradation signals in the ubiquitin-proteasome system. | 
| + | - | nl | Nat Rev Mol Cell Biol 9(9):679-90 (2008) |