| Nr. | Year OPEN | Title | users say> | rate good | rate bad | no link | Citation |
StatinHeart failure (chronical)Thrombosis (BASKET)Heart (Atrial fibrillation)Premedication and perioperative medicineKidney (Chronic renal failure)Arterial hypertension (BASKET)Atherosclerosis (peripheral vessels)Kidney (Fibrosis)RAAS (ACE inhibitor)Lung (Fibrosis)COPDAcetylsalicylic acid AspirinInflammation resolutionLipoxinProtectinResolvinMaresinStroke (BASKET)Hypercholesterolemia autosomal recessiveHeart (Arrhythmia)Subarachnoid hemorrhageCardiovascular riskIntracerebral bleedingAortic valve (Stenosis and artificial valve)HDLRosuvastatinSimvastatinAtorvastatinProtein kinase B AktThrombosis (Prophylaxis)EzetimibeLipoprotein (Dyslipoproteinemia Hyperlipoproteinemia)TorcetrapibNiacinColesevelamAvasimibeFibrateImplitapideBlood coagulationEpstein barr virusMuscle (Diseases)CalcificationSepsisNephroprotective renoprotective agents| 1 | 2008 | Effects of statins in patients with chronic kidney disease: meta-analysis and meta-regression of randomised controlled trials. | 
| + | - | nl | BMJ 336(7645):645-51 (2008) Strippoli GF |
| 2 | 2010 | Use of statins in patients with chronic hepatitis C. | 
| + | - | nl | South Med J 103(10):1018-22; quiz 1023 (2010) |
| 3 | 2006 | Primary evaluation and management of statin therapy complications. | 
| + | - | nl | South Med J 99(3):250-6 (2006) |
| 4 | 2008 | Interaction between statins and clopidogrel: is there anything clinically relevant? | 
| + | - | nl | QJM 101(12):915-25 (2008) |
| 5 | 2006 | Statins in patients with chronic kidney disease: evidence from systematic reviews and randomized clinical trials. | 
| + | - | nl | PLoS Med 3(5):e123 (2006) |
| 6 | 2006 | Primary prevention of cardiovascular diseases with statin therapy: a meta-analysis of randomized controlled trials. | 
| + | - | nl | Arch Intern Med 166(21):2307-13 (2006) |
| 7 | 2002 | Therapy with hydroxymethylglutaryl coenzyme a reductase inhibitors (statins) and associated risk of incident cardiovascular events in older adults: evidence from the Cardiovascular Health Study. | 
| + | - | nl | Arch Intern Med 162(12):1395-400 (2002) Lemaitre RN |
| 8 | 1999 | Clinical outcomes in statin treatment trials: a meta-analysis. | 
| + | - | nl | Arch Intern Med 159(15):1793-802 (1999) |
| 9 | 2008 | Perioperative statins: more than lipid-lowering? | 
| + | - | nl | Cleve Clin J Med 75(9):654-62 (2008) |
| 10 | 2005 | Safety of statins: effects on muscle and the liver. | 
| + | - | nl | Cleve Clin J Med 72(11):990-3, 996-1001 (2005) |
| 11 | 2005 | Statins: the case for higher, individualized starting doses. | 
| + | - | nl | Cleve Clin J Med 72(9):811-6 (2005) Jones PH |
| 12 | 2001 | Statin myopathies: pathophysiologic and clinical perspectives. | 
| + | - | nl | Clin Invest Med 24(5):258-72 (2001) |
| 13 | 2004 | The cellular biochemistry of cholesterol and statins: insights into the pathophysiology and therapy of Alzheimer's disease. | 
| + | - | nl | CNS Drug Rev 10(2):127-46 (2004) |
| 14 | 2005 | Statins and cognition: what can we learn from existing randomized trials? | 
| + | - | nl | CNS Spectr 10(11):867-74 (2005) |
| 15 | 2006 | American, British and European recommendations for statins in the primary prevention of cardiovascular disease applied to British men studied prospectively. | 
| + | - | nl | Heart 92(9):1213-8 (2006) |
| 16 | 2009 | Reducing morbidity and mortality in high risk patients with statins. | 
| + | - | nl | Vasc Health Risk Manag 5(2):495-507 (2009) |
| 17 | 2008 | Clinical efficacy and safety of statins in managing cardiovascular risk. | 
| + | - | nl | Vasc Health Risk Manag 4(2):341-53 (2008) |
| 18 | 2005 | Ongoing clinical trials of the pleiotropic effects of statins. | 
| + | - | nl | Vasc Health Risk Manag 1(1):29-40 (2005) |
| 19 | 2006 | Statins in the treatment of chronic heart failure: biological and clinical considerations. | 
| + | - | nl | Cardiovasc Res 71(3):443-54 (2006) |
| 20 | 2005 | Cardiac effects of statins--advancements and open questions. | 
| + | - | nl | Cardiovasc Res 66(3):427-9 (2005) |
| 21 | 2005 | Statins--is there no end to their usefulness? | 
| + | - | nl | Cardiovasc Res 65(2):296-8 (2005) |
| 22 | 2001 | Vascular effects of HMG CoA-reductase inhibitors (statins) unrelated to cholesterol lowering: new concepts for cardiovascular disease. | 
| + | - | nl | Cardiovasc Res 49(2):281-7 (2001) |
| 23 | 2007 | A systematic review and economic evaluation of statins for the prevention of coronary events. | 
| + | - | nl | Health Technol Assess 11(14):1-160, iii-iv (2007) |
| 24 | 2003 | The statins as anticancer agents. | 
| + | - | nl | Clin Cancer Res 9(1):10-9 (2003) |
| 25 | 2006 | Why should statins prevent venous thromboembolism? A systematic literature search and a call for action. | 
| + | - | nl | J Thromb Haemost 4(9):1925-7 (2006) Squizzato A |
| 26 | 2009 | Narrative review: statin-related myopathy. | 
| + | - | nl | Ann Intern Med 150(12):858-68 (2009) |
| 27 | 2001 | Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. | 
| + | - | nl | Arterioscler Thromb Vasc Biol 21(11):1712-9 (2001) |
| 28 | 2009 | Inhibition of RhoA or Rac1? Mechanism of cholesterol-independent beneficial effects of statins. | 
| + | - | nl | Circ J 73(2):231-2 (2009) |
| 29 | 2007 | Peroxisome proliferator-activated receptors mediate pleiotropic actions of statins. | 
| + | - | nl | Circ Res 100(10):1394-5 (2007) Paumelle R |
| 30 | 2006 | Risks associated with statin therapy: a systematic overview of randomized clinical trials. | 
| + | - | nl | Circulation 114(25):2788-97 (2006) |
| 31 | 2007 | HMG-CoA reductase inhibitors and renal function. | 
| + | - | nl | Clin J Am Soc Nephrol 2(6):1100-3 (2007) Campese VM |
| 32 | 2009 | Statin-induced diabetes: will it change clinical practice? | 
| + | - | nl | Diabetes Care 32(10):1941-3 (2009) Belalcazar LM |
| 33 | 2009 | Statin therapy and risk of developing type 2 diabetes: a meta-analysis. | 
| + | - | nl | Diabetes Care 32(10):1924-9 (2009) |
| 34 | 2006 | Statins for improving renal outcomes: a meta-analysis. | 
| + | - | nl | J Am Soc Nephrol 17(7):2006-16 (2006) |
| 35 | 2006 | REVIEW: Efficacy and mechanisms of action of statins in the treatment of diabetic dyslipidemia. | 
| + | - | nl | J Clin Endocrinol Metab 91(2):383-92 (2006) |
| 36 | 2002 | Clinical review 145: Pleiotropic effects of statins: lipid reduction and beyond. | 
| + | - | nl | J Clin Endocrinol Metab 87(4):1451-8 (2002) |
| 37 | 1992 | The discovery and development of HMG-CoA reductase inhibitors. | 
| + | - | nl | J Lipid Res 33(11):1569-82 (1992) |
| 38 | 2006 | Statins and cancer risk: a meta-analysis. | 
| + | - | nl | JAMA 295(1):74-80 (2006) |
| 39 | 2007 | The use of statins in pediatrics: knowledge base, limitations, and future directions. | 
| + | - | nl | Pediatrics 119(2):370-80 (2007) |
| 40 | 2002 | ACC/AHA/NHLBI Clinical Advisory on the Use and Safety of Statins. | 
| + | - | nl | Stroke 33(9):2337-41 (2002) |
| 41 | 2005 | Pleiotropic effects of statins: benefit beyond cholesterol reduction? A meta-regression analysis. | 
| + | - | nl | J Am Coll Cardiol 46(10):1855-62 (2005) |
| 42 | 2008 | The efficacy and safety of intensive statin therapy: a meta-analysis of randomized trials. | 
| + | - | nl | CMAJ 178(5):576-84 (2008) |
| 43 | 2007 | Does pravastatin promote cancer in elderly patients? A meta-analysis. | 
| + | - | nl | CMAJ 176(5):649-54 (2007) Bonovas S |
| 44 | 2008 | Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism. | 
| + | - | nl | Am J Cardiovasc Drugs 8(6):373-418 (2008) |
| 45 | 2011 | Effect of statins on atrial fibrillation: collaborative meta-analysis of published and unpublished evidence from randomised controlled trials. | 
| + | - | nl | BMJ 342(-):d1250 (2011) |
| 46 | 2011 | Statin myopathy: a common dilemma not reflected in clinical trials. | 
| + | - | nl | Cleve Clin J Med 78(6):393-403 (2011) |
| 47 | 2009 | Statins and noncardiac surgery: current evidence and practical considerations. | 
| + | - | nl | Cleve Clin J Med 76 Suppl 4(-):S79-83 (2009) |
| 48 | 2007 | Effects of statins on renal function. | 
| + | - | nl | Mayo Clin Proc 82(11):1381-90 (2007) |
| 49 | 2007 | Do statins reduce blood pressure?: a meta-analysis of randomized, controlled trials. | 
| + | - | nl | Hypertension 49(4):792-8 (2007) |
| 50 | 2002 | Immunomodulatory effects of statins: mechanisms and potential impact on arteriosclerosis. | 
| + | - | nl | J Am Soc Nephrol 13(6):1673-81 (2002) |
| 51 | 2005 | Are 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors renoprotective? | 
| + | - | nl | J Am Soc Nephrol 16 Suppl 1(-):S11-7 (2005) |
| 52 | 2002 | Statin therapy: beyond cholesterol lowering and antiinflammatory effects. | 
| + | - | nl | Circulation 105(25):2937-8 (2002) |
| 53 | 2004 | Impact of angiotensin-converting enzyme inhibitors and statins on survival in idiopathic pulmonary fibrosis. | 
| + | - | nl | Chest 126(2):438-46 (2004) |
| 54 | 2009 | Statins in COPD: a systematic review. | 
| + | - | nl | Chest 136(3):734-43 (2009) |
| 55 | 2009 | Antimicrobial and immunomodulatory attributes of statins: relevance in solid-organ transplant recipients. | 
| + | - | nl | Clin Infect Dis 48(6):745-55 (2009) |
| 56 | 2011 | Mevalonate pathway is a novel target for hypertension. | 
| + | - | nl | Circ J 75(6):1318-9 (2011) Kishi T |
| 57 | 2010 | Sympathoinhibitory effects of atorvastatin in hypertension. | 
| + | - | nl | Circ J 74(12):2552-3 (2010) Kishi T |
| 58 | 2010 | Pleiotropic effects of statins. - Basic research and clinical perspectives -. | 
| + | - | nl | Circ J 74(5):818-26 (2010) |
| 59 | 2010 | Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins. | 
| + | - | nl | Circ Res 107(10):1170-84 (2010) |
| 60 | 2003 | Endothelium-dependent effects of statins. | 
| + | - | nl | Arterioscler Thromb Vasc Biol 23(5):729-36 (2003) |
| 61 | 2003 | Rapid effects of statins: from prophylaxis to therapy for ischemic stroke. | 
| + | - | nl | Arterioscler Thromb Vasc Biol 23(2):156-7 (2003) |
| 62 | 2007 | A systematic review and meta-analysis of statin therapy in children with familial hypercholesterolemia. | 
| + | - | nl | Arterioscler Thromb Vasc Biol 27(8):1803-10 (2007) |
| 63 | 2007 | Do statins have an antiarrhythmic activity? | 
| + | - | nl | Cardiovasc Res 75(1):10-20 (2007) |
| 64 | 2010 | Effect of statin treatment on vasospasm, delayed cerebral ischemia, and functional outcome in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis update. | 
| + | - | nl | Stroke 41(1):e47-52 (2010) |
| 65 | 2010 | 'Yes' or 'no' to routine statins after subarachnoid hemorrhage to prevent delayed cerebral ischaemia, vasospasm, and death? A cautionary tale of 2 meta-analyses. | 
| + | - | nl | Stroke 41(1):e1-2 (2010) Sandercock P |
| 66 | 2008 | Statin therapy for stroke prevention. | 
| + | - | nl | Stroke 39(3):1042-8 (2008) |
| 67 | 2008 | Effect of statins on intracerebral hemorrhage outcome and recurrence. | 
| + | - | nl | Stroke 39(7):2151-4 (2008) |
| 68 | 2004 | Statins for primary and secondary prevention of coronary heart disease. A scientific review. | 
| + | - | nl | Rev Port Cardiol 23(1):95-122 (2004) |
| 69 | 2007 | The role of statins in aortic stenosis. Myth or reality? | 
| + | - | nl | Rev Port Cardiol 26(1):51-62 (2007) |
| 70 | 2010 | Effect of statins on HDL-C: a complex process unrelated to changes in LDL-C: analysis of the VOYAGER Database. | 
| + | - | nl | J Lipid Res 51(6):1546-53 (2010) |
| 71 | 2008 | Pharmacogenomics of cardiovascular pharmacology: molecular network analysis in pleiotropic effects of statin -- an experimental elucidation of the pharmacologic action from protein-protein interaction analysis. | 
| + | - | nl | J Pharmacol Sci 107(1):15-9 (2008) |
| 72 | 2009 | ASH evidence-based guidelines: statins in the prevention of venous thromboembolism. | 
| + | - | nl | Hematology Am Soc Hematol Educ Program -(-):273-4 (2009) |
| 73 | 2006 | Lipid-lowering drugs. | 
| + | - | nl | Cell Mol Life Sci 63(10):1165-78 (2006) |
| 74 | 2002 | Isoprenoids as mediators of the biological effects of statins. | 
| + | - | nl | J Clin Invest 110(3):285-8 (2002) |
| 75 | 2002 | Statin drugs and dietary isoprenoids downregulate protein prenylation in signal transduction and are antithrombotic and prothrombolytic agents. | 
| + | - | nl | Biochemistry (Mosc) 67(1):85-91 (2002) |
| 76 | 2005 | HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma. | 
| + | - | nl | Br J Cancer 92(9):1593-8 (2005) |
| 77 | 2009 | Targeting targets for LDL-lowering therapy: lessons from the Collaborative Atorvastatin Diabetes Study (CARDS). | 
| + | - | nl | Clin Chem 55(3):391-3 (2009) |
| 78 | 2002 | Statins: rhabdomyolysis and myopathy. | 
| + | - | nl | CMAJ 166(1):85-6, 90-1 (2002) |
| 79 | 2011 | Novel mechanistic and clinical implications concerning the safety of statin discontinuation. | 
| + | - | nl | Pharmacol Rep 63(4):867-79 (2011) |
| 80 | 2011 | Statin-induced myopathies. | 
| + | - | nl | Pharmacol Rep 63(4):859-66 (2011) |
| 81 | 2005 | Drug-induced myopathies. An overview of the possible mechanisms. | 
| + | - | nl | Pharmacol Rep 57(1):23-34 (2005) |
| 82 | 2007 | Statins: a new insight into their mechanisms of action and consequent pleiotropic effects. | 
| + | - | nl | Pharmacol Rep 59(5):483-99 (2007) |
| 83 | 2010 | Do statins slow the process of calcification of aortic tissue valves? | 
| + | - | nl | Interact Cardiovasc Thorac Surg 11(3):297-301 (2010) |
| 84 | 2010 | Benefits of statin therapy and compliance in high risk cardiovascular patients. | 
| + | - | nl | Vasc Health Risk Manag 6(-):843-53 (2010) |
| 85 | 2009 | The acute (cerebro)vascular effects of statins. | 
| + | - | nl | Anesth Analg 109(2):572-84 (2009) |
| 86 | 2009 | Statins for all: the new premed? | 
| + | - | nl | Br J Anaesth 103(1):99-107 (2009) |
| 87 | 2008 | Statins and sepsis. | 
| + | - | nl | Br J Anaesth 100(3):288-98 (2008) |
| 88 | 2004 | Beneficial effects of statins on the kidney. | 
| + | - | nl | J Clin Pathol 57(7):673-4 (2004) |
| 89 | 2010 | A historical perspective on the discovery of statins. | 
| + | - | nl | Proc Jpn Acad Ser B Phys Biol Sci 86(5):484-93 (2010) |