Statics and trial design Bibliography of free accessible medical and biological reviews

Nr.	Year OPEN	Title	rate good	rate bad	no link	Citation
1	2006	A primer on the use of modern missing-data methods in psychosomatic medicine research.	+	-	nl	Psychosom Med 68(3):427-36 (2006)
2	1997	Multilevel statistical models for psychosomatic research.	+	-	nl	Psychosom Med 59(4):350-1 (1997) Berry CC
3	1991	Meta-analysis: a review.	+	-	nl	Psychosom Med 53(3):247-71 (1991)
4	2010	The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews.	+	-	nl	BMJ 340(-):c365 (2010)
5	2009	Novel methods to deal with publication biases: secondary analysis of antidepressant trials in the FDA trial registry database and related journal publications.	+	-	nl	BMJ 339(-):b2981 (2009)
6	2006	Ratio measures in leading medical journals: structured review of accessibility of underlying absolute risks.	+	-	nl	BMJ 333(7581):1248 (2006)
7	2006	Cochrane reviews v industry supported meta-analyses: we should read all reviews with caution.	+	-	nl	BMJ 333(7574):916 (2006)
8	2006	Cochrane reviews v industry supported meta-analyses: has Cochrane really achieved its goals?	+	-	nl	BMJ 333(7574):916 (2006)
9	2006	Cochrane reviews v industry supported meta-analyses: ten questions to assess bias in medical research.	+	-	nl	BMJ 333(7574):916-7 (2006)
10	2006	Cochrane reviews compared with industry supported meta-analyses and other meta-analyses of the same drugs: systematic review.	+	-	nl	BMJ 333(7572):782 (2006)
11	2006	The simplest statistical test: how to check for a difference between treatments.	+	-	nl	BMJ 332(7552):1256-8 (2006)
12	2005	Why clinicians are natural bayesians.	+	-	nl	BMJ 330(7499):1080-3 (2005)
13	2005	Readers guide to critical appraisal of cohort studies: 3. Analytical strategies to reduce confounding.	+	-	nl	BMJ 330(7498):1021-3 (2005)
14	2005	Reader's guide to critical appraisal of cohort studies: 2. Assessing potential for confounding.	+	-	nl	BMJ 330(7497):960-2 (2005)
15	2005	Reader's guide to critical appraisal of cohort studies: 1. Role and design.	+	-	nl	BMJ 330(7496):895-7 (2005)
16	2005	Optimal search strategies for retrieving systematic reviews from Medline: analytical survey.	+	-	nl	BMJ 330(7482):68 (2005)
17	2004	Diagnostic tests 4: likelihood ratios.	+	-	nl	BMJ 329(7458):168-9 (2004)
18	2004	The logrank test.	+	-	nl	BMJ 328(7447):1073 (2004)
19	2002	Power is indeed irrelevant in interpreting completed studies.	+	-	nl	BMJ 325(7375):1304 (2002)
20	2002	Post-randomisation exclusions: the intention to treat principle and excluding patients from analysis.	+	-	nl	BMJ 325(7365):652-4 (2002)
21	2001	Statistics notes: Analysing controlled trials with baseline and follow up measurements.	+	-	nl	BMJ 323(7321):1123-4 (2001)
22	2001	Sifting the evidence-what's wrong with significance tests?	+	-	nl	BMJ 322(7280):226-31 (2001)
23	2000	The risk of bias from omitted research.	+	-	nl	BMJ 321(7265):845-6 (2000)
24	2000	Statistics notes. The odds ratio.	+	-	nl	BMJ 320(7247):1468 (2000)
25	2000	Scientific, ethical, and logistical considerations in introducing a new operation: a retrospective cohort study from paediatric cardiac surgery.	+	-	nl	BMJ 320(7243):1168-73 (2000)
26	1999	How to randomise.	+	-	nl	BMJ 319(7211):703-4 (1999)
27	1999	What is meant by intention to treat analysis? Survey of published randomised controlled trials.	+	-	nl	BMJ 319(7211):670-4 (1999)
28	1999	A change in scientific approach: from alternation to randomised allocation in clinical trials in the 1940s.	+	-	nl	BMJ 319(7209):572-3 (1999)
29	1999	Understanding controlled trials. Randomisation methods: concealment.	+	-	nl	BMJ 319(7206):375-6 (1999)
30	1999	Statistics notes: variables and parameters.	+	-	nl	BMJ 318(7199):1667 (1999)
31	1999	Numbers needed to treat derived from meta-analyses--sometimes informative, usually misleading.	+	-	nl	BMJ 318(7197):1548-51 (1999)
32	1999	Statistics notes. Treatment allocation in controlled trials: why randomise?	+	-	nl	BMJ 318(7192):1209 (1999)
33	1998	Survival probabilities (the Kaplan-Meier method).	+	-	nl	BMJ 317(7172):1572 (1998)
34	1998	Confidence intervals for the number needed to treat.	+	-	nl	BMJ 317(7168):1309-12 (1998)
35	1998	Bayesians and frequentists.	+	-	nl	BMJ 317(7166):1151-60 (1998)
36	1998	When placebo controlled trials are essential and equivalence trials are inadequate.	+	-	nl	BMJ 317(7162):875-80 (1998)
37	1998	The intracluster correlation coefficient in cluster randomisation.	+	-	nl	BMJ 316(7142):1455 (1998)
38	1998	What's wrong with Bonferroni adjustments.	+	-	nl	BMJ 316(7139):1236-8 (1998)
39	1998	When can odds ratios mislead?	+	-	nl	BMJ 316(7136):989-91 (1998)
40	1998	Understanding controlled trials. What is a patient preference trial?	+	-	nl	BMJ 316(7128):360 (1998)
41	1998	Meta-analysis. Unresolved issues and future developments.	+	-	nl	BMJ 316(7126):221-5 (1998)
42	1998	Understanding controlled trials. Why are randomised controlled trials important?	+	-	nl	BMJ 316(7126):201 (1998)
43	1998	Spurious precision? Meta-analysis of observational studies.	+	-	nl	BMJ 316(7125):140-4 (1998)
44	1998	Statistics notes. Weighted comparison of means.	+	-	nl	BMJ 316(7125):129 (1998)
45	1997	Meta-analysis. Beyond the grand mean?	+	-	nl	BMJ 315(7122):1610-4 (1997)
46	1997	Papers that summarise other papers (systematic reviews and meta-analyses).	+	-	nl	BMJ 315(7109):672-5 (1997)
47	1997	Statistics notes. Trials randomised in clusters.	+	-	nl	BMJ 315(7108):600 (1997)
48	1997	How to read a paper. Statistics for the non-statistician. II: "Significant" relations and their pitfalls.	+	-	nl	BMJ 315(7105):422-5 (1997)
49	1997	How to read a paper. Statistics for the non-statistician. I: Different types of data need different statistical tests.	+	-	nl	BMJ 315(7104):364-6 (1997)
50	1997	Major journals should peer review trials at protocol stage.	+	-	nl	BMJ 314(7095):1691-2 (1997)
51	1997	Statistics notes. Units of analysis.	+	-	nl	BMJ 314(7098):1874 (1997)
52	1996	Statistics notes. Logarithms.	+	-	nl	BMJ 312(7032):700 (1996) Bland JM
53	1995	Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons.	+	-	nl	BMJ 311(7013):1145-8 (1995)
54	1994	Identifying relevant studies for systematic reviews.	+	-	nl	BMJ 309(6964):1286-91 (1994)
55	1994	Meta-analysis and its problems.	+	-	nl	BMJ 309(6957):789-92 (1994)
56	1994	Some examples of regression towards the mean.	+	-	nl	BMJ 309(6957):780 (1994)
57	1994	Systematic reviews. Some examples.	+	-	nl	BMJ 309(6956):719-21 (1994)
58	1994	Checklists for review articles.	+	-	nl	BMJ 309(6955):648-51 (1994)
59	1994	Rationale for systematic reviews.	+	-	nl	BMJ 309(6954):597-9 (1994)
60	1985	Death of a volunteer.	+	-	nl	Br Med J (Clin Res Ed) 290(6479):1369-70 (1985)
61	1983	Statistical guidelines for contributors to medical journals.	+	-	nl	Br Med J (Clin Res Ed) 286(6376):1489-93 (1983)
62	1979	The case-control study.	+	-	nl	Br Med J 2(6195):884-5 (1979)
63	1992	Why clinical trials fail: the hidden assumptions of clinical trials.	+	-	nl	South Med J 85(2):117-8 (1992)
64	2002	The nature of truth: Simpson's Paradox and the limits of statistical data.	+	-	nl	QJM 95(4):247-9 (2002)
65	2000	Confidence limits and the limits of confidence.	+	-	nl	QJM 93(2):121-4 (2000)
66	1999	Bootstrapping: estimating confidence intervals for cost-effectiveness ratios.	+	-	nl	QJM 92(3):177-82 (1999)
67	1998	The significance of non-significance.	+	-	nl	QJM 91(9):647-53 (1998)
68	1998	Likelihood ratios: getting diagnostic testing into perspective.	+	-	nl	QJM 91(4):247-58 (1998)
69	2009	Issues on the selection of non-inferiority margin in clinical trials.	+	-	nl	Chin Med J (Engl) 122(4):466-70 (2009)
70	2008	Imputation methods for missing outcome data in meta-analysis of clinical trials.	+	-	nl	Clin Trials 5(3):225-39 (2008)
71	2005	On criteria for evaluating models of absolute risk.	+	-	nl	Biostatistics 6(2):227-39 (2005)
72	2001	Rethinking historical controls.	+	-	nl	Biostatistics 2(4):383-96 (2001)
73	2004	Twenty statistical errors even you can find in biomedical research articles.	+	-	nl	Croat Med J 45(4):361-70 (2004)
74	2009	Incorporating multiple interventions in meta-analysis: an evaluation of the mixed treatment comparison with the adjusted indirect comparison.	+	-	nl	Trials 10(-):86 (2009)
75	2009	Design, analysis, and presentation of crossover trials.	+	-	nl	Trials 10(-):27 (2009)
76	2008	A review of RCTs in four medical journals to assess the use of imputation to overcome missing data in quality of life outcomes.	+	-	nl	Trials 9(-):51 (2008)
77	2009	Evaluation and recommendations on good clinical laboratory practice guidelines for phase I-III clinical trials.	+	-	nl	PLoS Med 6(5):e1000067 (2009)
78	2009	Preventing bias in cluster randomised trials.	+	-	nl	PLoS Med 6(5):e1000065 (2009)
79	2008	In the era of systematic reviews, does the size of an individual trial still matter.	+	-	nl	PLoS Med 5(1):e4 (2008)
80	2009	A systematic review of the reporting of Data Monitoring Committees' roles, interim analysis and early termination in pediatric clinical trials.	+	-	nl	BMC Pediatr 9(-):77 (2009)
81	2006	Conducting research in individual patients: lessons learnt from two series of N-of-1 trials.	+	-	nl	BMC Fam Pract 7(-):54 (2006)
82	2008	Teaching statistics in biology: using inquiry-based learning to strengthen understanding of statistical analysis in biology laboratory courses.	+	-	nl	CBE Life Sci Educ 7(3):317-26 (2008)
83	2009	Application of multivariate probabilistic (Bayesian) networks to substance use disorder risk stratification and cost estimation.	+	-	nl	Perspect Health Inf Manag 6(-):1b (2009)
84	2009	The use of older studies in meta-analyses of medical interventions: a survey.	+	-	nl	Open Med 3(2):e62-8 (2009)
85	2008	Meta-analysis of multi-arm trials using empirical logistic transform.	+	-	nl	Open Med Inform J 2(-):112-6 (2008)
86	2009	Meta-analysis: A brief introduction.	+	-	nl	Clin Transl Sci 2(5):374-8 (2009)
87	2009	Bayesian classification of clinical practice guidelines.	+	-	nl	Arch Intern Med 169(15):1431-5 (2009)
88	2004	Statistical issues in interpreting clinical trials.	+	-	nl	J Intern Med 255(5):529-37 (2004)
89	2004	On the evolution of statistical methods as applied to clinical trials.	+	-	nl	J Intern Med 255(5):521-8 (2004)
90	1997	Interpretation of data from multiple trials: a critical review.	+	-	nl	J Intern Med 241(3):177-83 (1997)
91	2007	Power: not only a matter of numbers, but also of design.	+	-	nl	Neth J Med 65(6):197-8 (2007)
92	2008	Meta-analysis: Its strengths and limitations.	+	-	nl	Cleve Clin J Med 75(6):431-9 (2008) Walker E
93	2008	Meta-analyses, metaphysics, and reality.	+	-	nl	Cleve Clin J Med 75(6):400 (2008)
94	1999	Misuse of correlation and regression in three medical journals.	+	-	nl	J R Soc Med 92(3):123-8 (1999)
95	1996	Systematic reviews.	+	-	nl	J R Soc Med 89(9):538 (1996)
96	1995	Pitfalls in the interpretation of studies: III.	+	-	nl	J R Soc Med 88(5):241-3 (1995)
97	1995	Pitfalls in the interpretation of studies: I.	+	-	nl	J R Soc Med 88(1):2-4 (1995)
98	2009	Standing on the shoulders of giants: Introduction to systematic reviews and meta-analyses.	+	-	nl	Can Fam Physician 55(11):1155-6 (2009)
99	2001	Hypothesis: the research page. Part 3: Power, sample size, and clinical significance.	+	-	nl	Can Fam Physician 47(-):1441-3, 1450-3 (2001)
100	2008	Tips and tricks in performing a systematic review--chapter 4.	+	-	nl	Br J Gen Pract 58(547):136 (2008)
101	2007	Tips and tricks in performing a systematic review.	+	-	nl	Br J Gen Pract 57(545):999 (2007)
102	2007	Tips and tricks in performing a systematic review.	+	-	nl	Br J Gen Pract 57(538):425 (2007)
103	1996	Is there evidence that megatrials are based on a methodological mistake?	+	-	nl	Br J Gen Pract 46(412):688 (1996)
104	1996	Megatrials are based on a methodological mistake.	+	-	nl	Br J Gen Pract 46(408):429-31 (1996)
105	2004	On the nature and analysis of clustered data.	+	-	nl	Ann Fam Med 2(3):199-200 (2004)
106	1979	The four basic types of evaluation: clinical reviews, clinical trials, program reviews, and program trials.	+	-	nl	Public Health Rep 94(3):210-5 (1979)
107	1997	Statistics in the journal--significance, confidence, and all that.	+	-	nl	Am J Public Health 87(7):1092-5 (1997)
108	1991	The importance of assessing the fit of logistic regression models: a case study.	+	-	nl	Am J Public Health 81(12):1630-5 (1991)
109	1984	Consensus methods: characteristics and guidelines for use.	+	-	nl	Am J Public Health 74(9):979-83 (1984)
110	2009	Interpreting results in 2 x 2 tables: part 9 of a series on evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 106(48):795-800 (2009)
111	2009	Placebo: misunderstandings and prejudices.	+	-	nl	Dtsch Arztebl Int 106(46):751-5 (2009)
112	2009	Avoiding bias in observational studies: part 8 in a series of articles on evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 106(41):664-8 (2009)
113	2009	Descriptive statistics: the specification of statistical measures and their presentation in tables and graphs. Part 7 of a series on evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 106(36):578-83 (2009)
114	2009	Systematic literature reviews and meta-analyses: part 6 of a series on evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 106(27):456-63 (2009)
115	2009	Requirements and assessment of laboratory tests: Part 5 of a series on evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 106(24):403-6 (2009)
116	2009	Study design in medical research: part 2 of a series on the evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 106(11):184-9 (2009)
117	2009	Critical appraisal of scientific articles: part 1 of a series on evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 106(7):100-5 (2009)
118	2008	Independent predictors from stepwise logistic regression may be nothing more than publishable P values.	+	-	nl	Anesth Analg 107(6):1775-8 (2008)
119	2005	The legend of the P value.	+	-	nl	Anesth Analg 101(5):1454-6 (2005)
120	2006	Better methods for meta-analysis available.	+	-	nl	Anesthesiology 104(6):1350 (2006)
121	2000	Current issues in clinical trial design: superiority versus equivalency studies.	+	-	nl	Anesthesiology 92(6):1814-20 (2000)
122	2000	Randomized and nonrandomized clinical studies: statistical considerations.	+	-	nl	Anesthesiology 92(4):928-30 (2000)
123	1993	Pitfalls in performing meta-analysis: I.	+	-	nl	Anesthesiology 79(2):405 (1993)
124	1993	Pitfalls in performing meta-analysis: II.	+	-	nl	Anesthesiology 79(2):406-8 (1993)
125	2008	Bench-to-bedside review: avoiding pitfalls in critical care meta-analysis--funnel plots, risk estimates, types of heterogeneity, baseline risk and the ecologic fallacy.	+	-	nl	Crit Care 12(4):220 (2008)
126	2005	A systematic evaluation of the quality of meta-analyses in the critical care literature.	+	-	nl	Crit Care 9(5):R575-82 (2005)
127	2004	Statistics review 13: receiver operating characteristic curves.	+	-	nl	Crit Care 8(6):508-12 (2004)
128	2005	Statistics review 14: Logistic regression.	+	-	nl	Crit Care 9(1):112-8 (2005)
129	2005	Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility. Pro: Futility stopping can speed up the development of effective treatments.	+	-	nl	Crit Care 9(1):34-6; discussion 34-6 (2005)
130	2004	Statistics review 10: further nonparametric methods.	+	-	nl	Crit Care 8(3):196-9 (2004)
131	2004	Statistics review 9: one-way analysis of variance.	+	-	nl	Crit Care 8(2):130-6 (2004)
132	2004	Statistics review 12: survival analysis.	+	-	nl	Crit Care 8(5):389-94 (2004)
133	2004	Statistics review 11: assessing risk.	+	-	nl	Crit Care 8(4):287-91 (2004)
134	2004	Statistics review 8: Qualitative data - tests of association.	+	-	nl	Crit Care 8(1):46-53 (2004)
135	2003	Statistics review 7: Correlation and regression.	+	-	nl	Crit Care 7(6):451-9 (2003)
136	2002	Statistics review 5: Comparison of means.	+	-	nl	Crit Care 6(5):424-8 (2002)
137	2002	Statistics review 4: sample size calculations.	+	-	nl	Crit Care 6(4):335-41 (2002)
138	2002	Statistics review 3: hypothesis testing and P values.	+	-	nl	Crit Care 6(3):222-5 (2002)
139	2002	Statistics review 6: Nonparametric methods.	+	-	nl	Crit Care 6(6):509-13 (2002)
140	2002	Statistics review 2: samples and populations.	+	-	nl	Crit Care 6(2):143-8 (2002)
141	2002	Statistics review 1: presenting and summarising data.	+	-	nl	Crit Care 6(1):66-71 (2002)
142	2005	Advanced statistics: how to determine whether your intervention is different, at least as effective as, or equivalent: a basic introduction.	+	-	nl	Acad Emerg Med 12(6):536-42 (2005)
143	2004	Advanced statistics: understanding medical record review (MRR) studies.	+	-	nl	Acad Emerg Med 11(2):187-92 (2004)
144	2003	Bayesian modeling and real-world problems.	+	-	nl	Acad Emerg Med 10(7):780-2 (2003) Lewis RJ
145	2001	Are clinician-investigators Bayesian?	+	-	nl	Acad Emerg Med 8(12):1179-81 (2001) Lewis RJ
146	2000	Research fundamentals: statistical considerations in research design: a simple person's approach.	+	-	nl	Acad Emerg Med 7(2):194-9 (2000)
147	1999	Systematic reviews: a logical methodological extension of evidence-based medicine.	+	-	nl	Acad Emerg Med 6(12):1255-60 (1999)
148	1998	Parametric statistical tests: unnecessary assumptions, computers, and the search for the trustworthy p-value.	+	-	nl	Acad Emerg Med 5(11):1048-50 (1998)
149	1997	Recommended guidelines for reviewing, reporting, and conducting research on in-hospital resuscitation: the in-hospital "Utstein style". A statement for health care professionals from the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, the Australian Resuscitation Council, and the Resuscitation Councils of Southern Africa.	+	-	nl	Acad Emerg Med 4(6):603-27 (1997)
150	2003	Statistical consideration for research.	+	-	nl	Emerg Med J 20(3):258-62 (2003)
151	2003	Designing a research project: randomised controlled trials and their principles.	+	-	nl	Emerg Med J 20(2):164-8 (2003)
152	2003	Observational research methods. Research design II: cohort, cross sectional, and case-control studies.	+	-	nl	Emerg Med J 20(1):54-60 (2003)
153	2002	Overview of research designs.	+	-	nl	Emerg Med J 19(6):546-9 (2002)
154	2001	Article 8. An introduction to hypothesis testing. Non-parametric comparison of two groups-1.	+	-	nl	Emerg Med J 18(4):276-82 (2001)
155	2007	Statistics in review. Part 2: generalised linear models, time-to-event and time-series analysis, evidence synthesis and clinical trials.	+	-	nl	Crit Care Resusc 9(2):187-97 (2007)
156	2007	Statistics in review Part I: graphics, data summary and linear models.	+	-	nl	Crit Care Resusc 9(1):81-90 (2007)
157	2004	Critical care trials: sample size, power and interpretation.	+	-	nl	Crit Care Resusc 6(4):239-42 (2004)
158	2001	Reporting of clinical trials using group sequential methods.	+	-	nl	Crit Care Resusc 3(3):146-7 (2001)
159	2000	Relative risks: relative benefits.	+	-	nl	Crit Care Resusc 2(4):244-5 (2000)
160	2000	The value of the number-needed-to-treat method in antiepileptic drug trials.	+	-	nl	Epilepsia 41(4):440-6 (2000)
161	2004	Methods for analysis of skewed data distributions in psychiatric clinical studies: working with many zero values.	+	-	nl	Am J Psychiatry 161(7):1159-68 (2004)
162	2004	Pitfalls of meta-analyses.	+	-	nl	Am J Psychiatry 161(6):1131 (2004)
163	2010	Statistics in experimental cerebrovascular research: comparison of more than two groups with a continuous outcome variable.	+	-	nl	J Cereb Blood Flow Metab 30(9):1558-63 (2010)
164	2005	From the descriptive towards inferential statistics: hundred years since conception of the Student's t-distribution.	+	-	nl	Neuro Endocrinol Lett 26(3):167-71 (2005)
165	2007	Simulation performance checklist generation using the Delphi technique.	+	-	nl	Can J Anaesth 54(12):992-7 (2007)
166	1997	Systematic reviews: the case for rigorous methods and rigorous reporting.	+	-	nl	Can J Anaesth 44(4):350-3 (1997)
167	2007	Consent bias in research: how to avoid it.	+	-	nl	Heart 93(9):1024-5 (2007) Junghans C
168	2006	The value of risk scores.	+	-	nl	Heart 92(12):1713-4 (2006) Jurgensen JS
169	2000	Evaluation of large scale clinical trials and their application to usual practice.	+	-	nl	Heart 84(6):679-84 (2000)
170	1988	The end of the p value?	+	-	nl	Br Heart J 60(3):177-80 (1988)
171	1989	Understanding investigative clinical trials.	+	-	nl	J Vasc Surg 9(4):609-18 (1989)
172	2006	Methodological issues in cardiovascular epidemiology: the risk of determining absolute risk through statistical models.	+	-	nl	Vasc Health Risk Manag 2(3):309-15 (2006)
173	2007	Statistics in pharmacology.	+	-	nl	Br J Pharmacol 152(3):291-3 (2007) Spina D
174	2007	Bayesian modelling and ROC analysis to predict placebo responders using clinical score measured in the initial weeks of treatment in depression trials.	+	-	nl	Br J Clin Pharmacol 63(5):595-613 (2007)
175	2004	What is a clinical trial?	+	-	nl	Br J Clin Pharmacol 58(1):1-3 (2004)
176	2004	The revision of the Declaration of Helsinki: past, present and future.	+	-	nl	Br J Clin Pharmacol 57(6):695-713 (2004)
177	2002	Is intent-to-treat analysis always (ever) enough?	+	-	nl	Br J Clin Pharmacol 54(2):203-11 (2002)
178	2001	Points to consider on switching between superiority and non-inferiority.	+	-	nl	Br J Clin Pharmacol 52(3):223-8 (2001)
179	2001	Switching between superiority and non-inferiority: an introductory note.	+	-	nl	Br J Clin Pharmacol 52(3):221 (2001)
180	2001	Switching between superiority and non-inferiority.	+	-	nl	Br J Clin Pharmacol 52(3):219 (2001)
181	2001	Stopping rules for phase II studies.	+	-	nl	Br J Clin Pharmacol 51(6):523-9 (2001)
182	1979	Validity of cross-over trials.	+	-	nl	Br J Clin Pharmacol 8(1):5-6 (1979)
183	1977	Significant or important?	+	-	nl	Br J Clin Pharmacol 4(4):411-2 (1977)
184	2006	Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies.	+	-	nl	Pharmacol Rev 58(3):621-81 (2006)
185	2005	Regression methods in the empiric analysis of health care data.	+	-	nl	J Manag Care Pharm 11(3):240-51 (2005)
186	2005	Clinical data gap between phase III clinical trials (pre-marketing) and phase IV (post-marketing) studies: evaluation of etanercept in rheumatoid arthritis.	+	-	nl	Can J Clin Pharmacol 12(3):e254-63 (2005)
187	2005	Modeling nonlinear dose-response relationships in epidemiologic studies: statistical approaches and practical challenges.	+	-	nl	Dose Response 3(4):474-90 (2005)
188	2005	The causes and effects of socio-demographic exclusions from clinical trials.	+	-	nl	Health Technol Assess 9(38):iii-iv, ix-x, 1-152 (2005)
189	2005	Lay public's understanding of equipoise and randomisation in randomised controlled trials.	+	-	nl	Health Technol Assess 9(8):1-192, iii-iv (2005)
190	2005	Issues in data monitoring and interim analysis of trials.	+	-	nl	Health Technol Assess 9(7):1-238, iii-iv (2005)
191	2004	Identification and assessment of ongoing trials in health technology assessment reviews.	+	-	nl	Health Technol Assess 8(44):iii, 1-87 (2004)
192	2003	Evaluating non-randomised intervention studies.	+	-	nl	Health Technol Assess 7(27):iii-x, 1-173 (2003)
193	2001	Statistical assessment of the learning curves of health technologies.	+	-	nl	Health Technol Assess 5(12):1-79 (2001)
194	2000	Bayesian methods in health technology assessment: a review.	+	-	nl	Health Technol Assess 4(38):1-130 (2000)
195	2000	An introduction to statistical methods for health technology assessment.	+	-	nl	Health Technol Assess 4(8):i-iv, 1-59 (2000)
196	1999	Factors that limit the quality, number and progress of randomised controlled trials.	+	-	nl	Health Technol Assess 3(20):1-143 (1999)
197	1998	Systematic reviews of trials and other studies.	+	-	nl	Health Technol Assess 2(19):1-276 (1998)
198	1998	Qualitative research methods in health technology assessment: a review of the literature.	+	-	nl	Health Technol Assess 2(16):iii-ix, 1-274 (1998)
199	1998	Choosing between randomised and non-randomised studies: a systematic review.	+	-	nl	Health Technol Assess 2(13):i-iv, 1-124 (1998)
200	1998	Consensus development methods, and their use in clinical guideline development.	+	-	nl	Health Technol Assess 2(3):i-iv, 1-88 (1998)
201	2006	The (relative) risks of using odds ratios.	+	-	nl	Arch Dermatol 142(6):761-4 (2006)
202	2004	Statistical significance and clinical relevance: the importance of power in clinical trials in dermatology.	+	-	nl	Arch Dermatol 140(12):1520-3 (2004)
203	2004	Hazard ratio in clinical trials.	+	-	nl	Antimicrob Agents Chemother 48(8):2787-92 (2004)
204	1990	Statistical methods in microbiology.	+	-	nl	Clin Microbiol Rev 3(3):219-26 (1990)
205	2008	Position paper: recommended design features of future clinical trials of antibacterial agents for community-acquired pneumonia.	+	-	nl	Clin Infect Dis 47 Suppl 3(-):S249-65 (2008)
206	2008	Issues in noninferiority trials: the evidence in community-acquired pneumonia.	+	-	nl	Clin Infect Dis 47 Suppl 3(-):S108-20 (2008)
207	2005	Basic statistical considerations in virological experiments.	+	-	nl	J Virol 79(2):669-76 (2005)
208	1991	Statistical methods applied in microbiology and epidemiology.	+	-	nl	Epidemiol Infect 107(3):467-78 (1991)
209	2009	Grading quality of evidence and strength of recommendations in clinical practice guidelines. Part 1 of 3. An overview of the GRADE approach and grading quality of evidence about interventions.	+	-	nl	Allergy 64(5):669-77 (2009)
210	2002	Statistical issues--significantly important in medical research.	+	-	nl	Allergy 57(2):76-82 (2002)
211	2003	Review of the use of statistics in infection and immunity.	+	-	nl	Infect Immun 71(12):6689-92 (2003)
212	2007	A guide to modern statistical analysis of immunological data.	+	-	nl	BMC Immunol 8(-):27 (2007)
213	1999	Study design and hypothesis testing: issues in the evaluation of evidence from research in nutritional epidemiology.	+	-	nl	Am J Clin Nutr 69(6):1315S-1321S (1999)
214	1997	Statistical design of calibration studies.	+	-	nl	Am J Clin Nutr 65(4 Suppl):1187S-1189S (1997)
215	1997	Regression calibration method for correcting measurement-error bias in nutritional epidemiology.	+	-	nl	Am J Clin Nutr 65(4 Suppl):1179S-1186S (1997)
216	2007	Time-dependent spectral analysis of epidemiological time-series with wavelets.	+	-	nl	J R Soc Interface 4(15):625-36 (2007)
217	2008	Use of game-theoretical methods in biochemistry and biophysics.	+	-	nl	J Biol Phys 34(1-2):1-17 (2008)
218	2007	Computing power in case-control association studies through the use of quadratic approximations: application to meta-statistics.	+	-	nl	Ann Hum Genet 71(Pt 2):262-70 (2007)
219	2009	Factor-analytic models for genotype x environment type problems and structured covariance matrices.	+	-	nl	Genet Sel Evol 41(-):21 (2009)
220	2008	Parameter expansion for estimation of reduced rank covariance matrices.	+	-	nl	Genet Sel Evol 40(1):3-24 (2008)
221	2007	Analysis of the real EADGENE data set: multivariate approaches and post analysis (open access publication).	+	-	nl	Genet Sel Evol 39(6):651-68 (2007)
222	2007	Analysis of the real EADGENE data set: comparison of methods and guidelines for data normalisation and selection of differentially expressed genes (open access publication).	+	-	nl	Genet Sel Evol 39(6):633-50 (2007)
223	2007	The EADGENE Microarray Data Analysis Workshop (open access publication).	+	-	nl	Genet Sel Evol 39(6):621-31 (2007)
224	2008	The role of causal reasoning in understanding Simpson's paradox, Lord's paradox, and the suppression effect: covariate selection in the analysis of observational studies.	+	-	nl	Emerg Themes Epidemiol 5(-):5 (2008)
225	1994	Survey of methods and statistical models used in the analysis of occupational cohort studies.	+	-	nl	Occup Environ Med 51(10):649-55 (1994)
226	2009	Epidemiological methods to tackle causal questions.	+	-	nl	Int J Epidemiol 38(1):3-6 (2009)
227	2009	Apparently conclusive meta-analyses may be inconclusive--Trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses.	+	-	nl	Int J Epidemiol 38(1):287-98 (2009)
228	2008	Analysis of 2 x 2 tables of frequencies: matching test to experimental design.	+	-	nl	Int J Epidemiol 37(6):1430-5 (2008)
229	2007	Bayesian perspectives for epidemiological research. II. Regression analysis.	+	-	nl	Int J Epidemiol 36(1):195-202 (2007)
230	2006	Regression dilution methods for meta-analysis: assessing long-term variability in plasma fibrinogen among 27,247 adults in 15 prospective studies.	+	-	nl	Int J Epidemiol 35(6):1570-8 (2006)
231	2005	Regression models for twin studies: a critical review.	+	-	nl	Int J Epidemiol 34(5):1089-99 (2005)
232	2005	Commentary: Empirical evidence of attrition bias in clinical trials.	+	-	nl	Int J Epidemiol 34(1):87-8 (2005) Juni P
233	2005	Investigating patient exclusion bias in meta-analysis.	+	-	nl	Int J Epidemiol 34(1):79-87 (2005)
234	2005	Regression to the mean: what it is and how to deal with it.	+	-	nl	Int J Epidemiol 34(1):215-20 (2005)
235	2005	Comparison of imputation and modelling methods in the analysis of a physical activity trial with missing outcomes.	+	-	nl	Int J Epidemiol 34(1):89-99 (2005)
236	2004	Mendelian randomization: prospects, potentials, and limitations.	+	-	nl	Int J Epidemiol 33(1):30-42 (2004)
237	2002	Probabilistic record linkage and a method to calculate the positive predictive value.	+	-	nl	Int J Epidemiol 31(6):1246-52 (2002)
238	2002	An overview of relations among causal modelling methods.	+	-	nl	Int J Epidemiol 31(5):1030-7 (2002)
239	2002	Direction and impact of language bias in meta-analyses of controlled trials: empirical study.	+	-	nl	Int J Epidemiol 31(1):115-23 (2002)
240	2002	Being sceptical about meta-analyses: a Bayesian perspective on magnesium trials in myocardial infarction.	+	-	nl	Int J Epidemiol 31(1):96-104 (2002)
241	2002	Asymmetric funnel plots and publication bias in meta-analyses of diagnostic accuracy.	+	-	nl	Int J Epidemiol 31(1):88-95 (2002)
242	2002	Commentary: improving pooled analyses in epidemiology.	+	-	nl	Int J Epidemiol 31(1):86-7 (2002) Friedenreich CM
243	2002	Can we individualize the 'number needed to treat'? An empirical study of summary effect measures in meta-analyses.	+	-	nl	Int J Epidemiol 31(1):72-6 (2002)
244	2001	Capture-recapture methods--useful or misleading?	+	-	nl	Int J Epidemiol 30(1):12-4 (2001)
245	1999	Simple sample size calculation for cluster-randomized trials.	+	-	nl	Int J Epidemiol 28(2):319-26 (1999)
246	1998	A review of statistical methods for estimating the risk of vertical human immunodeficiency virus transmission.	+	-	nl	Int J Epidemiol 27(6):1064-7 (1998)
247	1997	Regression models for ordinal responses: a review of methods and applications.	+	-	nl	Int J Epidemiol 26(6):1323-33 (1997)
248	1997	On the use of causal criteria.	+	-	nl	Int J Epidemiol 26(6):1137-41 (1997)
249	2009	The quality of meta-analyses of genetic association studies: a review with recommendations.	+	-	nl	Am J Epidemiol 170(11):1333-43 (2009)
250	2009	Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases.	+	-	nl	Am J Epidemiol 170(3):269-79 (2009)
251	2009	Type of alcoholic beverage and risk of head and neck cancer--a pooled analysis within the INHANCE Consortium.	+	-	nl	Am J Epidemiol 169(2):132-42 (2009)
252	2008	Combining matched and unmatched control groups in case-control studies.	+	-	nl	Am J Epidemiol 168(10):1204-10 (2008)
253	2008	Effect of formal statistical significance on the credibility of observational associations.	+	-	nl	Am J Epidemiol 168(4):374-83; discussion 384-90 (2008)
254	2007	Should meta-analyses of interventions include observational studies in addition to randomized controlled trials? A critical examination of underlying principles.	+	-	nl	Am J Epidemiol 166(10):1203-9 (2007)
255	2007	Turning the pump handle: evolving methods for integrating the evidence on gene-disease association.	+	-	nl	Am J Epidemiol 166(8):863-6 (2007)
256	2006	Bias in clinical intervention research.	+	-	nl	Am J Epidemiol 163(6):493-501 (2006)
257	2006	Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials.	+	-	nl	Am J Epidemiol 163(5):397-403 (2006)
258	2006	Statistical issues in life course epidemiology.	+	-	nl	Am J Epidemiol 163(1):84-96 (2006)
259	2005	Interrater reliability: completing the methods description in medical records review studies.	+	-	nl	Am J Epidemiol 161(10):974-7 (2005)
260	2004	Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker.	+	-	nl	Am J Epidemiol 159(9):882-90 (2004)
261	2002	Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations.	+	-	nl	Am J Epidemiol 156(4):300-10 (2002)
262	2000	Invited commentary: insulin resistance syndrome? Syndrome X? Multiple metabolic syndrome? A syndrome at all? Factor analysis reveals patterns in the fabric of correlated metabolic risk factors.	+	-	nl	Am J Epidemiol 152(10):908-11; discussion 912 (2000) Meigs JB
263	2000	Bias in the evaluation of low-magnitude associations: an empirical perspective.	+	-	nl	Am J Epidemiol 151(10):939-45 (2000)
264	2000	Problems due to small samples and sparse data in conditional logistic regression analysis.	+	-	nl	Am J Epidemiol 151(5):531-9 (2000)
265	1999	Random-effects meta-analyses are not always conservative.	+	-	nl	Am J Epidemiol 150(5):469-75 (1999)
266	1999	Invited commentary: propensity scores.	+	-	nl	Am J Epidemiol 150(4):327-33 (1999)
267	1999	Evaluation of old and new tests of heterogeneity in epidemiologic meta-analysis.	+	-	nl	Am J Epidemiol 150(2):206-15 (1999)
268	1999	Presenting statistical uncertainty in trends and dose-response relations.	+	-	nl	Am J Epidemiol 149(12):1077-86 (1999)
269	1998	Prediction and cross-validation of neural networks versus logistic regression: using hepatic disorders as an example.	+	-	nl	Am J Epidemiol 147(4):407-13 (1998)
270	1997	Comparison of effect estimates from a meta-analysis of summary data from published studies and from a meta-analysis using individual patient data for ovarian cancer studies.	+	-	nl	Am J Epidemiol 145(10):917-25 (1997)
271	2003	Matched cohort methods for injury research.	+	-	nl	Epidemiol Rev 25(-):43-50 (2003)
272	2002	Beyond intention to treat.	+	-	nl	Epidemiol Rev 24(1):85-90 (2002)
273	2002	Community-based health intervention trials: an overview of methodological issues.	+	-	nl	Epidemiol Rev 24(1):72-9 (2002)
274	2002	Special issues related to randomized trials of primary prevention.	+	-	nl	Epidemiol Rev 24(1):67-71 (2002)
275	2002	Ethics in the design and conduct of clinical trials.	+	-	nl	Epidemiol Rev 24(1):54-8 (2002)
276	2002	Design of randomized trials.	+	-	nl	Epidemiol Rev 24(1):4-11 (2002)
277	2002	Sample size calculations for randomized controlled trials.	+	-	nl	Epidemiol Rev 24(1):39-53 (2002)
278	2002	Analysis of randomized controlled trials.	+	-	nl	Epidemiol Rev 24(1):26-38 (2002)
279	2002	Management and conduct of randomized controlled trials.	+	-	nl	Epidemiol Rev 24(1):12-25 (2002)
280	2000	Statistics.	+	-	nl	Epidemiol Rev 22(1):126-30 (2000)
281	1999	Spatial analytical methods and geographic information systems: use in health research and epidemiology.	+	-	nl	Epidemiol Rev 21(2):143-61 (1999)
282	1999	Design and interpretation of vaccine field studies.	+	-	nl	Epidemiol Rev 21(1):73-88 (1999)
283	1999	Use of the case-control approach in vaccine evaluation: efficacy and adverse effects.	+	-	nl	Epidemiol Rev 21(1):56-72 (1999)
284	1999	Francis field trial of inactivated poliomyelitis vaccine: background and lessons for today.	+	-	nl	Epidemiol Rev 21(1):7-23 (1999)
285	1998	New techniques for the analysis of cohort studies.	+	-	nl	Epidemiol Rev 20(1):122-34 (1998)
286	1998	Use of computerized record linkage in cohort studies.	+	-	nl	Epidemiol Rev 20(1):112-21 (1998)
287	1998	Growth and development of term children born with low birth weight: effects of genetic and environmental factors.	+	-	nl	J Pediatr 133(1):67-72 (1998) Strauss RS
288	1998	Approaches for conducting large cohort studies.	+	-	nl	Epidemiol Rev 20(1):91-9 (1998)
289	1998	Population-based cohort studies.	+	-	nl	Epidemiol Rev 20(1):81-90 (1998)
290	1998	Quality assurance and quality control in longitudinal studies.	+	-	nl	Epidemiol Rev 20(1):71-80 (1998)
291	1998	Retaining and tracking cohort study members.	+	-	nl	Epidemiol Rev 20(1):57-70 (1998)
292	1998	Exposure measurement in cohort studies: the challenges of prospective data collection.	+	-	nl	Epidemiol Rev 20(1):43-56 (1998)
293	1998	Methodological issues for biomarkers and intermediate outcomes in cohort studies.	+	-	nl	Epidemiol Rev 20(1):29-42 (1998)
294	1998	Outcomes in cohort studies.	+	-	nl	Epidemiol Rev 20(1):15-28 (1998)
295	1997	Ethical and legal issues in genetic epidemiology.	+	-	nl	Epidemiol Rev 19(1):163-74 (1997)
296	1997	DNA banking in epidemiologic studies.	+	-	nl	Epidemiol Rev 19(1):156-62 (1997)
297	1997	Population studies of allele frequencies in single gene disorders: methodological and policy considerations.	+	-	nl	Epidemiol Rev 19(1):52-60 (1997)
298	1997	Evolving methods in genetic epidemiology. IV. Approaches to non-Mendelian inheritance.	+	-	nl	Epidemiol Rev 19(1):44-51 (1997)
299	1997	Evolving methods in genetic epidemiology. III. Gene-environment interaction in epidemiologic research.	+	-	nl	Epidemiol Rev 19(1):33-43 (1997)
300	2003	Number needed to treat (NNT): implication in rheumatology clinical practice.	+	-	nl	Ann Rheum Dis 62(4):316-21 (2003)
301	2004	A surplus of positive trials: weighing biases and reconsidering equipoise.	+	-	nl	Arthritis Res Ther 6(3):117-9 (2004)
302	2008	Systematic review and meta-analysis: when one study is just not enough.	+	-	nl	Clin J Am Soc Nephrol 3(1):253-60 (2008)
303	2007	Practice recommendations based on low, very low, and missing evidence.	+	-	nl	Clin J Am Soc Nephrol 2(1):11-2 (2007) Coyne DW
304	2009	Reporting results of orthopaedic research: confidence intervals and p values.	+	-	nl	Clin Orthop Relat Res 467(10):2736-7 (2009) Porcher R
305	1993	What price inconclusive clinical trials?	+	-	nl	Ann R Coll Surg Engl 75(3):145-6 (1993)
306	2004	Users' guide to the surgical literature: how to use a systematic literature review and meta-analysis.	+	-	nl	Can J Surg 47(1):60-7 (2004)
307	2002	Users' guide to the surgical literature: how to use an article reporting population-based volume-outcome relationships in surgery.	+	-	nl	Can J Surg 45(2):109-15 (2002)
308	2007	Is MEDLINE alone enough for a meta-analysis?	+	-	nl	Aliment Pharmacol Ther 26(1):125-6; author reply 126 (2007)
309	2008	Case-control study design: what, when, and why?	+	-	nl	J Thorac Oncol 3(12):1371-2 (2008)
310	2007	The randomized discontinuation trial: a phase II design to assess growth-inhibitory agents.	+	-	nl	Mol Cancer Ther 6(4):1180-5 (2007)
311	2002	Novel endpoints and design of early clinical trials.	+	-	nl	Ann Oncol 13 Suppl 4(-):139-43 (2002)
312	2002	Designing randomised trials: both large and small trials are needed.	+	-	nl	Ann Oncol 13 Suppl 4(-):131-8 (2002)
313	2002	Evaluation of response: new and standard criteria.	+	-	nl	Ann Oncol 13 Suppl 4(-):127-9 (2002)
314	2003	Survival analysis part IV: further concepts and methods in survival analysis.	+	-	nl	Br J Cancer 89(5):781-6 (2003)
315	2003	Survival analysis Part III: multivariate data analysis -- choosing a model and assessing its adequacy and fit.	+	-	nl	Br J Cancer 89(4):605-11 (2003)
316	2003	Survival analysis part I: basic concepts and first analyses.	+	-	nl	Br J Cancer 89(2):232-8 (2003)
317	1996	Multistage designs for phase II clinical trials: statistical issues in cancer research.	+	-	nl	Br J Cancer 74(8):1317-20 (1996)
318	1995	Sample size: how many patients are necessary?	+	-	nl	Br J Cancer 72(1):1-9 (1995)
319	1993	Intention to treat--who should use ITT?	+	-	nl	Br J Cancer 68(4):647-50 (1993)
320	1993	Surrogate endpoints.	+	-	nl	Br J Cancer 68(3):457-9 (1993)
321	1993	Current statistical issues in clinical cancer research.	+	-	nl	Br J Cancer 68(3):455-6 (1993)
322	2008	Systematic review of statistical methods used in molecular marker studies in cancer.	+	-	nl	Cancer 112(8):1862-8 (2008)
323	2008	Barriers to recruiting underrepresented populations to cancer clinical trials: a systematic review.	+	-	nl	Cancer 112(2):228-42 (2008)
324	2007	The hazards of intermediate endpoints.	+	-	nl	Cancer 110(9):1877-9 (2007)
325	2007	Risks and benefits associated with novel phase 1 oncology trial designs.	+	-	nl	Cancer 110(5):1115-24 (2007)
326	2002	Current concepts in radiation enteritis and implications for future clinical trials.	+	-	nl	Cancer 95(5):1151-63 (2002)
327	2009	Monitoring for lack of benefit: a critical component of a randomized clinical trial.	+	-	nl	J Clin Oncol 27(4):629-33 (2009)
328	2009	Considerations for the use of imaging tools for phase II treatment trials in oncology.	+	-	nl	Clin Cancer Res 15(6):1891-7 (2009)
329	2009	Randomized phase II designs.	+	-	nl	Clin Cancer Res 15(6):1883-90 (2009)
330	2009	Effective incorporation of biomarkers into phase II trials.	+	-	nl	Clin Cancer Res 15(6):1898-905 (2009)
331	2009	Alternate endpoints for screening phase II studies.	+	-	nl	Clin Cancer Res 15(6):1873-82 (2009)
332	2009	Novel designs and end points for phase II clinical trials.	+	-	nl	Clin Cancer Res 15(6):1866-72 (2009)
333	2008	The ethics of phase 0 oncology trials.	+	-	nl	Clin Cancer Res 14(12):3692-7 (2008)
334	2008	Phase 0 trials: an industry perspective.	+	-	nl	Clin Cancer Res 14(12):3683-8 (2008)
335	2008	The development of phase I cancer trial methodologies: the use of pharmacokinetic and pharmacodynamic end points sets the scene for phase 0 cancer clinical trials.	+	-	nl	Clin Cancer Res 14(12):3664-9 (2008)
336	2007	Trends in the use and role of biomarkers in phase I oncology trials.	+	-	nl	Clin Cancer Res 13(22 Pt 1):6719-26 (2007) Goulart BH
337	2007	Biomarkers in phase I oncology trials: signal, noise, or expensive distraction?	+	-	nl	Clin Cancer Res 13(22 Pt 1):6545-8 (2007)
338	2002	Biostatistical approaches for modeling longitudinal and event time data.	+	-	nl	Clin Cancer Res 8(8):2473-4 (2002)
339	1997	The scientific basis of clinical trials: statistical aspects.	+	-	nl	Clin Cancer Res 3(12 Pt 2):2587-90 (1997)
340	2009	Dose escalation methods in phase I cancer clinical trials.	+	-	nl	J Natl Cancer Inst 101(10):708-20 (2009)
341	1999	Incremental costs of enrolling cancer patients in clinical trials: a population-based study.	+	-	nl	J Natl Cancer Inst 91(10):847-53 (1999) Wagner JL
342	2008	The clinical significance of statistical significance.	+	-	nl	Oncologist 13(11):1129-33 (2008)
343	2009	Editorial on hypothesis and objectives in clinical trials: superiority, equivalence and non-inferiority.	+	-	nl	Thromb J 7(-):3 (2009)
344	1997	Tyranny of the p-value: the conflict between statistical significance and common sense.	+	-	nl	J Dent Res 76(1):534-6 (1997)
345	1990	Statistical management of data in clinical research.	+	-	nl	Crit Rev Oral Biol Med 1(1):55-66 (1990)
346	2005	Synthesizing medical evidence: systematic reviews and metaanalyses.	+	-	nl	Neurosurg Focus 19(4):E5 (2005)
347	2008	When is a negative phase II trial truly negative?	+	-	nl	Am J Respir Crit Care Med 178(6):554-5 (2008) Rubenfeld GD
348	2004	The ethical conduct of clinical research involving critically ill patients in the United States and Canada: principles and recommendations.	+	-	nl	Am J Respir Crit Care Med 170(12):1375-84 (2004)
349	2004	Positive clinical trials: understand the control group before implementing the result.	+	-	nl	Am J Respir Crit Care Med 170(3):223-6 (2004)
350	1998	Number needed to treat and relative risk reduction.	+	-	nl	Ann Intern Med 128(1):72-3 (1998)
351	1995	Discordance between meta-analyses and large-scale randomized, controlled trials. Examples from the management of acute myocardial infarction.	+	-	nl	Ann Intern Med 123(11):873-7 (1995)
352	2005	Understanding systematic reviews and meta-analysis.	+	-	nl	Arch Dis Child 90(8):845-8 (2005)
353	2004	GRADE: levels of evidence and grades of recommendation.	+	-	nl	Arch Dis Child 89(5):489 (2004)
354	1995	Statistics from the inside. 16. Multiple regression (2).	+	-	nl	Arch Dis Child 73(3):270-4 (1995)
355	1994	Statistics from the inside. 13. Probability and decisions.	+	-	nl	Arch Dis Child 71(1):90-4 (1994)
356	1993	10. Counted data (2).	+	-	nl	Arch Dis Child 68(6):800-2 (1993)
357	1993	Counted data (1).	+	-	nl	Arch Dis Child 68(2):246-9 (1993)
358	1992	Statistics from the inside. 7. Regression and correlation.	+	-	nl	Arch Dis Child 67(10):1306-9 (1992)
359	1992	Statistics from the inside. 6. Data structures (continued).	+	-	nl	Arch Dis Child 67(6):757-9 (1992)
360	2007	Documenting research in scientific articles: Guidelines for authors: 3. Reporting multivariate analyses.	+	-	nl	Chest 131(2):628-32 (2007)
361	2007	Documenting research in scientific articles: guidelines for authors: 2. Reporting hypothesis tests.	+	-	nl	Chest 131(1):317-9 (2007)
362	2006	Documenting research in scientific articles: guidelines for authors: reporting research designs and activities.	+	-	nl	Chest 130(4):1263-8 (2006)
363	2002	The design of randomized clinical trials in critically ill patients.	+	-	nl	Chest 121(4):1290-300 (2002)
364	2000	Reality and meta-analyses.	+	-	nl	Chest 118(3):835-6 (2000) Machtay M
365	2000	Is meta-analysis a metaphysical or a scientific method?	+	-	nl	Chest 118(3):832-4 (2000)
366	1999	Is meta-analysis really meta-physics?	+	-	nl	Chest 116(2):539-42 (1999)
367	2002	Advice on statistical analysis for Circulation Research.	+	-	nl	Circ Res 91(8):662-71 (2002)
368	2008	A primer in longitudinal data analysis.	+	-	nl	Circulation 118(19):2005-10 (2008)
369	2008	Some old and some new statistical tools for outcomes research.	+	-	nl	Circulation 118(8):872-84 (2008)
370	2008	Survival methods: additional topics.	+	-	nl	Circulation 117(22):2949-55 (2008)
371	2008	Methods and limitations of assessing new noninvasive tests: Part II: Outcomes-based validation and reliability assessment of noninvasive testing.	+	-	nl	Circulation 117(21):2793-801 (2008)
372	2008	Methods and limitations of assessing new noninvasive tests: part I: Anatomy-based validation of noninvasive testing.	+	-	nl	Circulation 117(20):2684-90 (2008)
373	2008	Logistic regression.	+	-	nl	Circulation 117(18):2395-9 (2008)
374	2008	Multiple linear regression: accounting for multiple simultaneous determinants of a continuous dependent variable.	+	-	nl	Circulation 117(13):1732-7 (2008)
375	2008	Analysis of variance.	+	-	nl	Circulation 117(1):115-21 (2008)
376	2007	Association studies in an era of too much information: clinical analysis of new biomarker and genetic data.	+	-	nl	Circulation 116(17):1866-70 (2007)
377	2007	What exactly do the trends mean?	+	-	nl	Circulation 116(13):1437-9 (2007) Falkner B
378	2007	Meta-analysis.	+	-	nl	Circulation 115(22):2870-5 (2007)
379	2007	Evaluation of randomized controlled trials.	+	-	nl	Circulation 115(13):1819-22 (2007)
380	2007	Design of randomized controlled trials.	+	-	nl	Circulation 115(9):1164-9 (2007)
381	2007	Use and misuse of the receiver operating characteristic curve in risk prediction.	+	-	nl	Circulation 115(7):928-35 (2007)
382	2007	Receiver-operating characteristic analysis for evaluating diagnostic tests and predictive models.	+	-	nl	Circulation 115(5):654-7 (2007)
383	2007	Survival methods.	+	-	nl	Circulation 115(1):109-13 (2007)
384	2006	Standards for statistical models used for public reporting of health outcomes: an American Heart Association Scientific Statement from the Quality of Care and Outcomes Research Interdisciplinary Writing Group: cosponsored by the Council on Epidemiology and Prevention and the Stroke Council. Endorsed by the American College of Cardiology Foundation.	+	-	nl	Circulation 113(3):456-62 (2006)
385	2004	The clinician as investigator: participating in clinical trials in the practice setting: Appendix 2: statistical concepts in study design and analysis.	+	-	nl	Circulation 109(21):e305-7 (2004)
386	2004	The clinician as investigator: participating in clinical trials in the practice setting: Appendix 1: fundamentals of study design.	+	-	nl	Circulation 109(21):e302-4 (2004)
387	2008	Interpreting results of clinical trials: a conceptual framework.	+	-	nl	Clin J Am Soc Nephrol 3(5):1246-52 (2008)
388	2006	Cohort studies: marching forward.	+	-	nl	Clin J Am Soc Nephrol 1(5):1117-23 (2006)
389	2006	The meta-analysis: supportive or illuminating?	+	-	nl	Eur Heart J 27(23):2744-5 (2006) Kowey PR
390	2006	Progress and problems for randomized clinical trials: from streptomycin to the era of megatrials.	+	-	nl	Eur Heart J 27(18):2158-64 (2006)
391	2006	Limitations of analyses of effectiveness using observational data.	+	-	nl	Eur Heart J 27(14):1642-3 (2006) Reeves BC
392	2004	Interpretation of observational studies.	+	-	nl	Heart 90(8):956-60 (2004)
393	2001	Absolute, attributable, and relative risk in the management of coronary heart disease.	+	-	nl	Heart 85(5):491-2 (2001)
394	2005	Statistical issues in the analysis of neuronal data.	+	-	nl	J Neurophysiol 94(1):8-25 (2005)
395	2007	The Bayesian clinician.	+	-	nl	J Postgrad Med 53(4):267-9 (2007)
396	1993	Statistics in medical research--III. Correlation and regression analysis.	+	-	nl	J Postgrad Med 39(4):235-43 (1993)
397	2007	Data extraction errors in meta-analyses that use standardized mean differences.	+	-	nl	JAMA 298(4):430-7 (2007)
398	2002	How statistical expertise is used in medical research.	+	-	nl	JAMA 287(21):2817-20 (2002)
399	2001	Comparison of evidence of treatment effects in randomized and nonrandomized studies.	+	-	nl	JAMA 286(7):821-30 (2001)
400	1998	Methodology and reports of systematic reviews and meta-analyses: a comparison of Cochrane reviews with articles published in paper-based journals.	+	-	nl	JAMA 280(3):278-80 (1998)
401	1998	Meta-analysis as a clinical tool in nephrology.	+	-	nl	Kidney Int 53(4):819-25 (1998)
402	2008	Clinical research of kidney diseases IV: Standard regression models.	+	-	nl	Nephrol Dial Transplant 23(2):475-82 (2008)
403	2007	P less than .05: what does it really mean?	+	-	nl	Pediatrics 119(3):608-10 (2007)
404	2002	Data and models determine treatment proposals--an illustration from meta-analysis.	+	-	nl	Postgrad Med J 78(917):131-4 (2002) Helfenstein U
405	2001	Balancing statistical and clinical significance in evaluating treatment effects.	+	-	nl	Postgrad Med J 77(905):201-4 (2001)
406	1998	Statistics in medicine: some considerations from a clinician's point of view.	+	-	nl	Postgrad Med J 74(876):577-8 (1998)
407	2000	Potential bias in Kaplan-Meier survival analysis applied to rheumatology drug studies.	+	-	nl	Rheumatology (Oxford) 39(1):1-2 (2000)
408	2005	When should you use statistics?	+	-	nl	Swiss Med Wkly 135(23-24):337-8 (2005)
409	2003	Statistics in medical research.	+	-	nl	Swiss Med Wkly 133(39-40):522-9 (2003) Sprent P
410	2003	Statistics in medicine.	+	-	nl	Swiss Med Wkly 133(39-40):521 (2003)
411	1991	Statistics in respiratory medicine. 3. Scale, parametric methods, and transformations.	+	-	nl	Thorax 46(7):536-8 (1991)
412	1991	Statistics in respiratory medicine. 2. Repeatability and method comparison.	+	-	nl	Thorax 46(6):454-6 (1991)
413	2005	A statistical evaluation of toxicity study designs for the estimation of the benchmark dose in continuous endpoints.	+	-	nl	Toxicol Sci 84(1):167-85 (2005)
414	2001	Statistical issues in the analysis of low-dose endocrine disruptor data.	+	-	nl	Toxicol Sci 61(2):201-10 (2001)
415	2006	Beyond randomized controlled trials: a critical comparison of trials with nonrandomized studies.	+	-	nl	Hepatology 44(5):1075-82 (2006)
416	1996	Meta-analysis: an introduction and point of view.	+	-	nl	Hepatology 23(4):917-28 (1996)
417	2008	Meta-analysis.	+	-	nl	J Am Coll Cardiol 52(3):237-8 (2008)
418	2004	Prior convictions: Bayesian approaches to the analysis and interpretation of clinical megatrials.	+	-	nl	J Am Coll Cardiol 43(11):1929-39 (2004)
419	2007	The radiology task: Bayesian theory and perception.	+	-	nl	Br J Radiol 80(954):389-91 (2007)
420	2007	Visual grading characteristics (VGC) analysis: a non-parametric rank-invariant statistical method for image quality evaluation.	+	-	nl	Br J Radiol 80(951):169-76 (2007)
421	2004	Randomized controlled trials.	+	-	nl	AJR Am J Roentgenol 183(6):1539-44 (2004)
422	2002	Statistically engineering the study for success.	+	-	nl	AJR Am J Roentgenol 179(1):47-52 (2002)
423	1988	Statistical techniques for medical decision making: applications to diagnostic radiology.	+	-	nl	AJR Am J Roentgenol 150(4):745-50 (1988)
424	2000	Randomized controlled trials are not appropriate for imaging technology evaluation.	+	-	nl	J Nucl Med 41(7):1125-6 (2000)
425	1998	Statistical analysis: the need, the concept, and the usage.	+	-	nl	Indian J Ophthalmol 46(1):51-8 (1998)
426	1996	Assessment of clinical significance: the number needed to treat.	+	-	nl	Indian J Ophthalmol 44(2):113-5 (1996)
427	2006	How to make clinical decisions from statistics.	+	-	nl	Clin Exp Optom 89(3):176-83 (2006)
428	2008	Statistics: understanding the jargon.	+	-	nl	Bull Soc Belge Ophtalmol -(309-310):7-9 (2008)
429	2005	Epidemiology for ophthalmologists: an introduction to concepts, study designs, and interpreting findings.	+	-	nl	Br J Ophthalmol 89(3):378-84 (2005)
430	2002	The determination of sample size in controlled clinical trials in ophthalmology.	+	-	nl	Br J Ophthalmol 86(9):946-7 (2002)
431	2009	Integration of evidence from multiple meta-analyses: a primer on umbrella reviews, treatment networks and multiple treatments meta-analyses.	+	-	nl	CMAJ 181(8):488-93 (2009)
432	2008	Ethics guidelines for clinical trials to be revised.	+	-	nl	CMAJ 178(2):138 (2008)
433	2007	The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey.	+	-	nl	CMAJ 176(8):1091-6 (2007)
434	2004	Tips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat.	+	-	nl	CMAJ 171(4):353-8 (2004) Barratt A
435	2001	Intention-to-treat principle.	+	-	nl	CMAJ 165(10):1339-41 (2001)
436	1995	Basic statistics for clinicians: 1. Hypothesis testing.	+	-	nl	CMAJ 152(1):27-32 (1995)
437	1989	Confidence intervals: from statistical significance to clinical significance.	+	-	nl	CMAJ 141(9):881-3 (1989)
438	2003	Special Topics III: bias.	+	-	nl	Radiology 229(3):617-21 (2003)
439	1999	Statistical methods for comparative qualitative analysis.	+	-	nl	Radiology 211(3):605-7 (1999)
440	2006	The value of a P value.	+	-	nl	AJNR Am J Neuroradiol 27(7):1389-90 (2006)
441	2002	N-of-1 randomized controlled trials ('N-of-1 trials'): singularly useful in geriatric medicine.	+	-	nl	Age Ageing 31(4):227-32 (2002)
442	2010	Recruitment and retention of patients into emergency medicine clinical trials.	+	-	nl	Acad Emerg Med 17(10):1104-12 (2010)
443	2005	Fundamental steps in experimental design for animal studies.	+	-	nl	Acta Cir Bras 20(1):2-8 (2005)
444	2008	Clinical research on new drugs (Phase I). Profile of scientific publications: data from the pre-clinical phase and bioethical aspects.	+	-	nl	Acta Cir Bras 23(6):531-5 (2008)
445	2009	Pitfalls in the design and analysis of paediatric clinical trials: a case of a 'failed' multi-centre study, and potential solutions.	+	-	nl	Acta Paediatr 98(2):385-91 (2009)
446	2011	Mixed method designs in implementation research.	+	-	nl	Adm Policy Ment Health 38(1):44-53 (2011)
447	2011	How helpful are meta-analyses in determining the best therapy of blood diseases?	+	-	nl	Acta Haematol 125(1-2):91-101 (2011)
448	2010	Investigator-initiated trials of targeted oncology agents: why independent research is at risk?	+	-	nl	Ann Oncol 21(8):1573-8 (2010)
449	2010	Looking for efficiency rather than efficacy in randomized controlled trials in oncology.	+	-	nl	Ann Oncol 21(7):1391-3 (2010)
450	2004	Statistical analyses of repeated measures in physiological research: a tutorial.	+	-	nl	Adv Physiol Educ 28(1-4):2-14 (2004)
451	2004	Analogies for understanding statistics.	+	-	nl	Adv Physiol Educ 28(1-4):124-5 (2004)
452	2008	Explorations in statistics: standard deviations and standard errors.	+	-	nl	Adv Physiol Educ 32(3):203-8 (2008)
453	2007	Minimal clinically important improvement/difference (MCII/MCID) and patient acceptable symptom state (PASS): what do these concepts mean?	+	-	nl	Ann Rheum Dis 66 Suppl 3(-):iii40-1 (2007)
454	2004	Model-based estimation of relative risks and other epidemiologic measures in studies of common outcomes and in case-control studies.	+	-	nl	Am J Epidemiol 160(4):301-5 (2004)
455	2004	Imputations of missing values in practice: results from imputations of serum cholesterol in 28 cohort studies.	+	-	nl	Am J Epidemiol 160(1):34-45 (2004)
456	2008	Use of multiple imputation in the epidemiologic literature.	+	-	nl	Am J Epidemiol 168(4):355-7 (2008)
457	2004	New applications of statistical tools in plant pathology.	+	-	nl	Phytopathology 94(9):999-1003 (2004)
458	2009	Design and debugging databases for statistical analysis.	+	-	nl	Allergol Immunopathol (Madr) 37(2):93-7 (2009)
459	2008	Issues related to the conduct of systematic reviews: a focus on the nutrition field.	+	-	nl	Am J Clin Nutr 88(5):1191-9 (2008)
460	2010	GRACE principles: recognizing high-quality observational studies of comparative effectiveness.	+	-	nl	Am J Manag Care 16(6):467-71 (2010) Dreyer NA
461	2004	Systematic reviews for evidence-based management: how to find them and what to do with them.	+	-	nl	Am J Manag Care 10(11 Pt 1):806-12 (2004)
462	2002	Designing studies to ensure that estimates of test accuracy are transferable.	+	-	nl	BMJ 324(7338):669-71 (2002)
463	2002	What to do about poor clinical performance in clinical trials.	+	-	nl	BMJ 324(7334):419-20 (2002)
464	2002	Peer review of statistics in medical research: the other problem.	+	-	nl	BMJ 324(7348):1271-3 (2002)
465	2011	Multiplicity of data in trial reports and the reliability of meta-analyses: empirical study.	+	-	nl	BMJ 343(-):d4829 (2011)
466	2004	What doesn't work and how to show it.	+	-	nl	BMJ 328(7438):473 (2004)
467	2004	Inappropriate use of randomised trials to evaluate complex phenomena: case study of vaginal breech delivery.	+	-	nl	BMJ 329(7473):1039-42 (2004)
468	2003	Strategy for randomised clinical trials in rare cancers.	+	-	nl	BMJ 327(7405):47-9 (2003)
469	2003	Ethics of clinical trials from a bayesian and decision analytic perspective: whose equipoise is it anyway?	+	-	nl	BMJ 326(7396):980-1 (2003)
470	2007	Uncertainty in heterogeneity estimates in meta-analyses.	+	-	nl	BMJ 335(7626):914-6 (2007)
471	2009	Written informed consent and selection bias in observational studies using medical records: systematic review.	+	-	nl	BMJ 338(-):b866 (2009)
472	2005	Identifying outcome reporting bias in randomised trials on PubMed: review of publications and survey of authors.	+	-	nl	BMJ 330(7494):753 (2005)
473	2005	Standard deviations and standard errors.	+	-	nl	BMJ 331(7521):903 (2005)
474	2008	Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study.	+	-	nl	BMJ 336(7644):601-5 (2008)
475	2006	Further lessons from the TGN1412 tragedy.	+	-	nl	BMJ 333(7562):270-1 (2006)
476	2009	What can we learn from design faults in the Women's Health Initiative randomized clinical trial?	+	-	nl	Bull NYU Hosp Jt Dis 67(2):226-9 (2009)
477	2009	Methods to analyze real-world databases and registries.	+	-	nl	Bull NYU Hosp Jt Dis 67(2):193-7 (2009)
478	2008	Some main problems eroding the credibility and relevance of randomized trials.	+	-	nl	Bull NYU Hosp Jt Dis 66(2):135-9 (2008)
479	2008	How to do human-subjects research if you do not have an institutional review board.	+	-	nl	Respir Care 53(10):1362-7 (2008)
480	2008	Practical tips for working effectively with your institutional review board.	+	-	nl	Respir Care 53(10):1354-61 (2008)
481	2008	Institutional review board consideration of chart reviews, case reports, and observational studies.	+	-	nl	Respir Care 53(10):1350-3 (2008)
482	2008	Protecting vulnerable subjects in clinical research: children, pregnant women, prisoners, and employees.	+	-	nl	Respir Care 53(10):1342-9 (2008)
483	2008	Informed consent: what is it? Who can give it? How do we improve it?	+	-	nl	Respir Care 53(10):1337-41 (2008)
484	2008	The purpose, composition, and function of an institutional review board: balancing priorities.	+	-	nl	Respir Care 53(10):1330-6 (2008)
485	2008	The historical, ethical, and legal background of human-subjects research.	+	-	nl	Respir Care 53(10):1325-9 (2008)
486	2008	The institutional review board and you.	+	-	nl	Respir Care 53(10):1324 (2008)
487	2009	Translating evidence into practice.	+	-	nl	Respir Care 54(10):1386-401 (2009)
488	2008	Dispelling the myths: calling for sex-specific reporting of trial results.	+	-	nl	Mayo Clin Proc 83(5):523-5 (2008)
489	2011	Review and classification of variability analysis techniques with clinical applications.	+	-	nl	Biomed Eng Online 10(-):90 (2011)
490	2011	A note on the use of the generalized odds ratio in meta-analysis of association studies involving bi- and tri-allelic polymorphisms.	+	-	nl	BMC Res Notes 4(-):172 (2011)
491	2009	Optimizing trial design: sequential, adaptive, and enrichment strategies.	+	-	nl	Circulation 119(4):597-605 (2009)
492	2003	An appraisal of multivariable logistic models in the pulmonary and critical care literature.	+	-	nl	Chest 123(3):923-8 (2003) Moss M
493	2008	From Delphi to knowledge and comfort: the devil is in the details.	+	-	nl	Chest 133(5):1060-2 (2008) Lessnau KD
494	2003	Correlation and simple linear regression.	+	-	nl	Radiology 227(3):617-22 (2003)
495	2008	Network meta-analysis: simultaneous meta-analysis of common antiplatelet regimens after transient ischaemic attack or stroke.	+	-	nl	Eur Heart J 29(9):1086-92 (2008)
496	2009	Need for ethics approval and patient consent in clinical research.	+	-	nl	Stroke 40(5):1555-6 (2009)
497	2007	Outcomes validity and reliability of the modified Rankin scale: implications for stroke clinical trials: a literature review and synthesis.	+	-	nl	Stroke 38(3):1091-6 (2007)
498	2006	How to design a clinical in cardiology. The main issues.	+	-	nl	Rev Port Cardiol 25(1):105-18 (2006)
499	2006	Types of clinical studies. Systematic reviews.	+	-	nl	Rev Port Cardiol 25(2):233-46 (2006)
500	2002	Subgroup analysis in therapeutic trials.	+	-	nl	Rev Port Cardiol 21(3):339-46 (2002)
501	2002	Basics of methodologic analysis of therapeutic trials. Part I: Validity of the results.	+	-	nl	Rev Port Cardiol 21(4):457-69 (2002)
502	2002	Intention-to-treat analysis in clinical trials: principles and practical importance.	+	-	nl	Rev Port Cardiol 21(10):1191-8 (2002)
503	2004	Randomization methods in clinical trials.	+	-	nl	Rev Port Cardiol 23(5):741-55 (2004)
504	2008	Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: Part 2: Randomized controlled trials.	+	-	nl	Pain Physician 11(6):717-73 (2008)
505	2005	Registering clinical trials.	+	-	nl	Pain Physician 8(3):249-50 (2005)
506	2009	Evidence-based medicine, systematic reviews, and guidelines in interventional pain management: Part 7: systematic reviews and meta-analyses of diagnostic accuracy studies.	+	-	nl	Pain Physician 12(6):929-63 (2009)
507	2003	Bayesian computation: a statistical revolution.	+	-	nl	Philos Transact A Math Phys Eng Sci 361(1813):2681-97 (2003)
508	2009	An overview of recent developments in genomics and associated statistical methods.	+	-	nl	Philos Transact A Math Phys Eng Sci 367(1906):4313-37 (2009)
509	2010	Development of anti-cancer drugs.	+	-	nl	Discov Med 10(53):355-62 (2010)
510	2011	Quantifying selective reporting and the Proteus phenomenon for multiple datasets with similar bias.	+	-	nl	PLoS One 6(3):e18362 (2011)
511	2011	GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets.	+	-	nl	PLoS One 6(2):e17259 (2011)
512	2011	Three-armed trials including placebo and no-treatment groups may be subject to publication bias: systematic review.	+	-	nl	PLoS One 6(5):e20679 (2011)
513	2010	Room for improvement in conducting and reporting non-inferiority randomized controlled trials on drugs: a systematic review.	+	-	nl	PLoS One 5(10):e13550 (2010)
514	2010	Obtaining valid laboratory data in clinical trials conducted in resource diverse settings: lessons learned from a microbicide phase III clinical trial.	+	-	nl	PLoS One 5(10):e13592 (2010)
515	2010	A generalized formula for converting chi-square tests to effect sizes for meta-analysis.	+	-	nl	PLoS One 5(4):e10059 (2010)
516	2007	Statistical reviewers improve reporting in biomedical articles: a randomized trial.	+	-	nl	PLoS One 2(3):e332 (2007)
517	2010	Phase III clinical trial development: a process of chutes and ladders.	+	-	nl	Clin Cancer Res 16(22):5381-9 (2010)
518	2010	Approaches to phase 1 clinical trial design focused on safety, efficiency, and selected patient populations: a report from the clinical trial design task force of the national cancer institute investigational drug steering committee.	+	-	nl	Clin Cancer Res 16(6):1726-36 (2010)
519	2010	Information needed to conduct first-in-human oncology trials in the United States: a view from a former FDA medical reviewer.	+	-	nl	Clin Cancer Res 16(6):1719-25 (2010)
520	2010	An overview of the optimal planning, design, and conduct of phase I studies of new therapeutics.	+	-	nl	Clin Cancer Res 16(6):1710-8 (2010)
521	2010	GCP data quality for early clinical development.	+	-	nl	Clin Cancer Res 16(6):1756-63 (2010)
522	2010	The design of phase II clinical trials testing cancer therapeutics: consensus recommendations from the clinical trial design task force of the national cancer institute investigational drug steering committee.	+	-	nl	Clin Cancer Res 16(6):1764-9 (2010)
523	2010	Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents.	+	-	nl	Clin Cancer Res 16(6):1745-55 (2010)
524	2007	Testing the wrong hypothesis in phase II oncology trials: there is a better alternative.	+	-	nl	Clin Cancer Res 13(3):781-2 (2007) Ratain MJ
525	2007	Phase 0 trials: are they ethically challenged?	+	-	nl	Clin Cancer Res 13(3):783-4 (2007)
526	2008	Statistical issues in translational cancer research.	+	-	nl	Clin Cancer Res 14(19):5954-8 (2008)
527	2010	New results will change the paradigm for phase I trials and drug approval.	+	-	nl	Oncologist 15(10):1023-5 (2010)
528	2010	The role of the U.S. Food and Drug Administration review process: clinical trial endpoints in oncology.	+	-	nl	Oncologist 15 Suppl 1(-):13-8 (2010)
529	2010	Combining targeted therapies: practical issues to consider at the bench and bedside.	+	-	nl	Oncologist 15(1):37-50 (2010)
530	2009	Bayesian statistics in oncology: a guide for the clinical investigator.	+	-	nl	Cancer 115(23):5371-81 (2009)
531	2007	Differences between a drug regimen employed in early phase 1 trials and the subsequent use of the agent in routine oncologic practice: a note of caution.	+	-	nl	Cancer 110(8):1644-7 (2007)
532	2009	Central pathology review in multicenter trials and studies: lessons from the nephroblastoma trials.	+	-	nl	Cancer 115(9):1977-83 (2009)
533	2003	Survival analysis part II: multivariate data analysis--an introduction to concepts and methods.	+	-	nl	Br J Cancer 89(3):431-6 (2003)
534	2008	Learning from past mistakes: assessing trial quality, power and eligibility in non-renal systemic lupus erythematosus randomized controlled trials.	+	-	nl	Rheumatology (Oxford) 47(9):1367-72 (2008)
535	2008	Most tumour necrosis factor inhibitor trials in rheumatology are undeservedly called 'efficacy and safety' trials: a survey of power considerations.	+	-	nl	Rheumatology (Oxford) 47(7):1054-7 (2008)
536	2008	Statistical evaluation of prognostic versus diagnostic models: beyond the ROC curve.	+	-	nl	Clin Chem 54(1):17-23 (2008)
537	2010	Corticosteroids for sepsis: registry versus Cochrane systematic review!	+	-	nl	Crit Care 14(4):185 (2010)
538	2010	Delta inflation: a bias in the design of randomized controlled trials in critical care medicine.	+	-	nl	Crit Care 14(2):R77 (2010)
539	2005	Trial registration report card.	+	-	nl	N Engl J Med 353(26):2809-11 (2005) Drazen JM
540	2005	Registries and registration of clinical trials.	+	-	nl	N Engl J Med 353(26):2811-2 (2005) Haug C
541	2004	Clinical trial registration: a statement from the International Committee of Medical Journal Editors.	+	-	nl	N Engl J Med 351(12):1250-1 (2004)
542	2007	Statistics in medicine--reporting of subgroup analyses in clinical trials.	+	-	nl	N Engl J Med 357(21):2189-94 (2007)
543	2010	Sample size calculation in clinical trials: part 13 of a series on evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 107(31-32):552-6 (2010)
544	2011	Survival analysis: part 15 of a series on evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 108(10):163-9 (2011)
545	2011	Randomized controlled trials-an indispensible part of clinical research.	+	-	nl	Dtsch Arztebl Int 108(39):661-2 (2011)
546	2010	Linear regression analysis: part 14 of a series on evaluation of scientific publications.	+	-	nl	Dtsch Arztebl Int 107(44):776-82 (2010)
547	2010	The financing of drug trials by pharmaceutical companies and its consequences. Part 1: a qualitative, systematic review of the literature on possible influences on the findings, protocols, and quality of drug trials.	+	-	nl	Dtsch Arztebl Int 107(16):279-85 (2010) Schott G
548	2010	The financing of drug trials by pharmaceutical companies and its consequences: part 2: a qualitative, systematic review of the literature on possible influences on authorship, access to trial data, and trial registration and publication.	+	-	nl	Dtsch Arztebl Int 107(17):295-301 (2010)
549	2003	Inclusion of patients in clinical trial analysis: the intention-to-treat principle.	+	-	nl	Med J Aust 179(8):438-40 (2003)
550	2004	Biostatistics 203. Survival analysis.	+	-	nl	Singapore Med J 45(6):249-56 (2004)
551	2004	Biostatistics 302. Principal component and factor analysis.	+	-	nl	Singapore Med J 45(12):558-65, quiz 566 (2004)
552	2005	Biostatistics 303. Discriminant analysis.	+	-	nl	Singapore Med J 46(2):54-61; quiz 62 (2005)
553	2005	Biostatistics 306. Log-linear models: poisson regression.	+	-	nl	Singapore Med J 46(8):377-85; quiz 386 (2005)
554	2004	Systematic review of statistical methods used to analyze Seattle Angina Questionnaire scores.	+	-	nl	Can J Cardiol 20(2):187-93 (2004)
555	2007	Statistical errors in medical research--a chronic disease?	+	-	nl	Swiss Med Wkly 137(3-4):41-3 (2007)
556	2007	Statistical errors in medical research--a review of common pitfalls.	+	-	nl	Swiss Med Wkly 137(3-4):44-9 (2007) Strasak AM
557	2004	Statistical methods for linking health, exposure, and hazards.	+	-	nl	Environ Health Perspect 112(14):1440-5 (2004) Mather FJ
558	2004	Accounting for historical information in designing experiments: the Bayesian approach.	+	-	nl	Ann Ist Super Sanita 40(2):173-9 (2004)
559	2007	Evidence-based medicine for rare diseases: implications for data interpretation and clinical trial design.	+	-	nl	Cancer Control 14(2):160-6 (2007)
560	2002	Confidence in statistical analysis.	+	-	nl	Br J Anaesth 89(6):807-10 (2002)
561	2003	Misuse of standard error of the mean (SEM) when reporting variability of a sample. A critical evaluation of four anaesthesia journals.	+	-	nl	Br J Anaesth 90(4):514-6 (2003)
562	2007	Using the Bland-Altman method to measure agreement with repeated measures.	+	-	nl	Br J Anaesth 99(3):309-11 (2007)
563	2010	Equivalence and noninferiority testing in anesthesiology research.	+	-	nl	Anesthesiology 113(4):779-81 (2010)
564	2010	Network meta-analysis on the log-hazard scale, combining count and hazard ratio statistics accounting for multi-arm trials: a tutorial.	+	-	nl	BMC Med Res Methodol 10(-):54 (2010)
565	2011	Questions asked and answered in pilot and feasibility randomized controlled trials.	+	-	nl	BMC Med Res Methodol 11(-):117 (2011)
566	2011	Simulation methods to estimate design power: an overview for applied research.	+	-	nl	BMC Med Res Methodol 11(-):94 (2011)
567	2011	The case study approach.	+	-	nl	BMC Med Res Methodol 11(-):100 (2011)
568	2002	Simpson's paradox and calculation of number needed to treat from meta-analysis.	+	-	nl	BMC Med Res Methodol 2(-):1 (2002)
569	2002	Pooling data for number needed to treat: no problems for apples.	+	-	nl	BMC Med Res Methodol 2():2 (2002) Moore RA
570	2002	Meta-analysis, Simpson's paradox, and the number needed to treat.	+	-	nl	BMC Med Res Methodol 2():3 (2002) Altman DG
571	2002	Markers for early detection of cancer: statistical guidelines for nested case-control studies.	+	-	nl	BMC Med Res Methodol 2(-):4 (2002)
572	2002	Do multiple outcome measures require p-value adjustment?	+	-	nl	BMC Med Res Methodol 2(-):8 (2002)
573	2002	Statistical issues in randomized trials of cancer screening.	+	-	nl	BMC Med Res Methodol 2(-):11 (2002)
574	2010	A systematic review of models to predict recruitment to multicentre clinical trials.	+	-	nl	BMC Med Res Methodol 10(-):63 (2010)
575	2010	What is a pilot or feasibility study? A review of current practice and editorial policy.	+	-	nl	BMC Med Res Methodol 10(-):67 (2010)
576	2011	Calculating unreported confidence intervals for paired data.	+	-	nl	BMC Med Res Methodol 11(-):66 (2011)
577	2011	Parametric methods outperformed non-parametric methods in comparisons of discrete numerical variables.	+	-	nl	BMC Med Res Methodol 11(-):44 (2011)
578	2011	Instrumental variable meta-analysis of individual patient data: application to adjust for treatment non-compliance.	+	-	nl	BMC Med Res Methodol 11(-):55 (2011)
579	2008	Regression toward the mean--a detection method for unknown population mean based on Mee and Chua's algorithm.	+	-	nl	BMC Med Res Methodol 8(-):52 (2008)
580	2008	Advantages of the nested case-control design in diagnostic research.	+	-	nl	BMC Med Res Methodol 8(-):48 (2008)
581	2005	Systems validation: application to statistical programs.	+	-	nl	BMC Med Res Methodol 5(1):3 (2005)
582	2009	Evidence synthesis as the key to more coherent and efficient research.	+	-	nl	BMC Med Res Methodol 9(-):29 (2009)
583	2008	The use of interim data and Data Monitoring Committee recommendations in randomized controlled trial reports: frequency, implications and potential sources of bias.	+	-	nl	BMC Med Res Methodol 8(-):12 (2008)
584	2008	Assessing the order of magnitude of outcomes in single-arm cohorts through systematic comparison with corresponding cohorts: an example from the AMOS study.	+	-	nl	BMC Med Res Methodol 8(-):11 (2008)
585	2008	The impact of consent on observational research: a comparison of outcomes from consenters and non consenters to an observational study.	+	-	nl	BMC Med Res Methodol 8(-):15 (2008)
586	2007	Phase 0 clinical trials in cancer drug development: from FDA guidance to clinical practice.	+	-	nl	Mol Interv 7(6):325-34 (2007)
587	2006	What are open-label extension studies for?	+	-	nl	J Rheumatol 33(4):642-3 (2006) Taylor WJ
588	2004	Trials are short, disease long: measuring drug utility beyond clinical trials.	+	-	nl	J Rheumatol 31(2):205-6 (2004)
589	2004	Are individual patient trials (n-of-1 trials) in rheumatology worth the extra effort?	+	-	nl	J Rheumatol 31(1):8-11 (2004)
590	2008	Do Lego guns cause crime?: A light-hearted review of case-control, cohort, and RCT study designs.	+	-	nl	Can Fam Physician 54(11):1635-6 (2008)
591	2009	Recruiting issues in community-based studies: some advice from lessons learned.	+	-	nl	Can Fam Physician 55(5):557-8 (2009)

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All data shown were primarily retrieved from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.