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  • SIRT1
  • beta cell (Pancreas)
  • Calcium (Intracellular)
  • P53
  • PGC1alpha
  • DNA (Methylation)
  • Histone deacetylase
  • Posttranslational protein modification
  • Histone demethylase
  • Nicotinamide phosphoribosyltransferase
  • Nicotinamide mononucleotide adenylyltransferase1
  • Nitric oxide NO
  • Atherosclerosis (peripheral vessels)
  • Nutrition (Neuroendocrinology)
  • Insulin (BASKET)
  • Leptin
  • Arcuate nucleus
  • FoxO1
  • Agouti related peptide AgRP
  • Circadian clock
  • Heme oxygenase
  • Phosphoenolpyruvate carboxykinase
  • Ppargc1alpha
  • Diabetes mellitus T2DM (Type2)
  • NAMPT
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    Citation
    12009The critical role of the class III histone deacetylase SIRT1 in cancer.



    +-nlCancer Res 69(5):1702-5 (2009)
    22010Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.



    +-nlAm J Physiol Endocrinol Metab 299(4):E517-32 (2010)
    32010SIRT1 and p53, effect on cancer, senescence and beyond.



    +-nlBiochim Biophys Acta 1804(8):1684-9 (2010)
    42010Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5.



    +-nlBiochim Biophys Acta 1804(8):1676-83 (2010)
    52010Biochemical effects of SIRT1 activators.



    +-nlBiochim Biophys Acta 1804(8):1626-34 (2010)
    62010SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions.



    +-nlBiochim Biophys Acta 1804(8):1666-75 (2010)
    72006SIRT1: linking adaptive cellular responses to aging-associated changes in organismal physiology.



    +-nlPhysiology (Bethesda) 21(-):404-10 (2006)
    82008NO targets SIRT1: a novel signaling network in endothelial senescence.



    +-nlArterioscler Thromb Vasc Biol 28(9):1577-9 (2008) Potente M
    92008Activating SIRT1: a new strategy to prevent atherosclerosis?



    +-nlCardiovasc Res 80(2):163-4 (2008) Brandes RP
    102010Roles of FoxO1 and Sirt1 in the central regulation of food intake.



    +-nlEndocr J 57(11):939-46 (2010)
    112005Transcriptional regulation of neuronal genes and its effect on neural functions: NAD-dependent histone deacetylase SIRT1 (Sir2alpha).



    +-nlJ Pharmacol Sci 98(3):200-4 (2005)
    122009SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age-related neoplasms.



    +-nlFASEB J 23(9):2803-9 (2009)
    132011Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models.



    +-nlAntioxid Redox Signal 14(4):649-61 (2011)
    142009Dietary activators of Sirt1.



    +-nlMol Cell Endocrinol 299(1):58-63 (2009)
    152009Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes.



    +-nlFront Biosci 14(-):2983-95 (2009)



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