| Nr. | Year OPEN | Title | users say> | rate good | rate bad | no link | Citation |
Prions and associated diseasesTauNervous system (Neurodegeneration)Insomnia| 1 | 1991 | From simplicity to complexity (1950-1990): the case of peptic ulceration--II. Animal studies. | 
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| 7 | 1998 | Bovine spongiform encephalopathy and new variant Creutzfeldt-Jakob disease. | 
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| 9 | 2009 | The transcellular spread of cytosolic amyloids, prions, and prionoids. | 
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| 10 | 2006 | New insights into prion structure and toxicity. | 
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| 11 | 2007 | Neurotoxic species in prion disease: a role for PrP isoforms? | 
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| 12 | 2006 | Prion diseases of humans and farm animals: epidemiology, genetics, and pathogenesis. | 
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| 13 | 2005 | Prion protein glycosylation. | 
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| 14 | 2004 | PrPc on the road: trafficking of the cellular prion protein. | 
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| 15 | 2003 | Cellular prion protein function in copper homeostasis and redox signalling at the synapse. | 
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| 16 | 2002 | Mayhem of the multiple mechanisms: modelling neurodegeneration in prion disease. | 
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| 17 | 1999 | Cellular biology of prion diseases. | 
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| 18 | 2002 | Current perspectives on bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease. | 
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| 19 | 2007 | Prions and prion diseases: fundamentals and mechanistic details. | 
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| 24 | 2006 | The expanding universe of prion diseases. | 
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| 25 | 2002 | Involvement of macrophages in the pathogenesis of transmissible spongiform encephalopathies. | 
| + | - | nl | Dev Immunol 9(1):19-27 (2002) |
| 26 | 2006 | The role of the cellular prion protein in the immune system. | 
| + | - | nl | Clin Exp Immunol 146(1):1-8 (2006) |
| 27 | 2003 | Variant Creutzfeldt-Jakob disease: pathology, epidemiology, and public health implications. | 
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| 28 | 2009 | Prion variants, species barriers, generation and propagation. | 
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| 29 | 2008 | Chemical and biophysical insights into the propagation of prion strains. | 
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| 30 | 2010 | Emergence and natural selection of drug-resistant prions. | 
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| 31 | 2008 | Review. The origin of the prion agent of kuru: molecular and biological strain typing. | 
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| 32 | 2008 | Review. Understanding kuru: the contribution of anthropology and medicine. | 
| + | - | nl | Philos Trans R Soc Lond B Biol Sci 363(1510):3715-20 (2008) Lindenbaum S |
| 33 | 2008 | Review. The epidemiology of kuru: monitoring the epidemic from its peak to its end. | 
| + | - | nl | Philos Trans R Soc Lond B Biol Sci 363(1510):3707-13 (2008) Alpers MP |
| 34 | 2008 | Review. Kuru and its contribution to medicine. | 
| + | - | nl | Philos Trans R Soc Lond B Biol Sci 363(1510):3697-700 (2008) Gajdusek DC |
| 35 | 2008 | Review. Lessons of kuru research: background to recent studies with some personal reflections. | 
| + | - | nl | Philos Trans R Soc Lond B Biol Sci 363(1510):3689-96 (2008) Collinge J |
| 36 | 2008 | Review. The neuropathology of kuru and variant Creutzfeldt-Jakob disease. | 
| + | - | nl | Philos Trans R Soc Lond B Biol Sci 363(1510):3685-7 (2008) McLean CA |
| 37 | 2008 | Review. The changing face of kuru: a personal perspective. | 
| + | - | nl | Philos Trans R Soc Lond B Biol Sci 363(1510):3679-84 (2008) Mathews JD |
| 38 | 2001 | Prion protein interconversions. | 
| + | - | nl | Philos Trans R Soc Lond B Biol Sci 356(1406):197-200; discussion 200-2 (2001) |
| 39 | 2001 | The molecular biology of prion propagation. | 
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| 40 | 2001 | Prions and the lymphoreticular system. | 
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| 41 | 2000 | Scrapie infections initiated at varying doses: an analysis of 117 titration experiments. | 
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| 42 | 2010 | The role of GPI-anchored PrP C in mediating the neurotoxic effect of scrapie prions in neurons. | 
| + | - | nl | Curr Issues Mol Biol 12(2):119-27 (2010) |
| 43 | 2010 | Targeting of the prion protein to the cytosol: mechanisms and consequences. | 
| + | - | nl | Curr Issues Mol Biol 12(2):109-18 (2010) |
| 44 | 2010 | Prion protein and metal interaction: physiological and pathological implications. | 
| + | - | nl | Curr Issues Mol Biol 12(2):99-107 (2010) |
| 45 | 2010 | Autophagy, prion infection and their mutual interactions. | 
| + | - | nl | Curr Issues Mol Biol 12(2):87-97 (2010) |
| 46 | 2010 | Prion neurotoxicity: insights from prion protein mutants. | 
| + | - | nl | Curr Issues Mol Biol 12(2):51-61 (2010) |
| 47 | 1999 | Cell biological studies of the prion protein. | 
| + | - | nl | Curr Issues Mol Biol 1(1-2):65-75 (1999) |
| 48 | 2008 | Physiology of the prion protein. | 
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| 49 | 1991 | Prions and prion proteins. | 
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| 50 | 2008 | Prion diseases: from protein to cell pathology. | 
| + | - | nl | Am J Pathol 172(3):555-65 (2008) |
| 51 | 1995 | Etiology and pathogenesis of prion diseases. | 
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| 52 | 1972 | Subacute spongiform virus encephalopathies. Scrapie, Kuru and Creutzfeldt-Jakob disease: a review. | 
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| 53 | 2006 | Emerging pharmacotherapies for Creutzfeldt-Jakob disease. | 
| + | - | nl | Arch Neurol 63(4):497-501 (2006) |
| 54 | 2005 | Human prion diseases: molecular and clinical aspects. | 
| + | - | nl | Arch Neurol 62(4):545-52 (2005) |
| 55 | 1999 | Creutzfeldt-Jakob disease with florid-type plaques after cadaveric dura mater grafting. | 
| + | - | nl | Arch Neurol 56(3):357-62 (1999) |
| 56 | 2004 | Prions in control of cell glycosylation. | 
| + | - | nl | Biochem J 380(Pt 2):e5-6 (2004) Hounsell EF |
| 57 | 1990 | Prion liposomes. | 
| + | - | nl | Biochem J 266(1):1-14 (1990) |
| 58 | 2006 | Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity. | 
| + | - | nl | Brain 129(Pt 9):2297-317 (2006) |
| 59 | 2006 | A systematic review of prion therapeutics in experimental models. | 
| + | - | nl | Brain 129(Pt 9):2241-65 (2006) |
| 60 | 1999 | How to improve the clinical diagnosis of Creutzfeldt-Jakob disease. | 
| + | - | nl | Brain 122 ( Pt 12)(-):2345-51 (1999) |
| 61 | 2000 | Pathogenesis of prion diseases: a progress report. | 
| + | - | nl | Cell Death Differ 7(10):889-902 (2000) |
| 62 | 2006 | Prion disease genetics. | 
| + | - | nl | Eur J Hum Genet 14(3):273-81 (2006) |
| 63 | 2002 | A critical review of the nature of the spongiform encephalopathy agent: protein theory versus virus theory. | 
| + | - | nl | Exp Biol Med (Maywood) 227(1):4-19 (2002) |
| 64 | 2001 | Lingering doubts about spongiform encephalopathy and Creutzfeldt-Jakob disease. | 
| + | - | nl | Exp Biol Med (Maywood) 226(7):640-52 (2001) |
| 65 | 2001 | A critical review of atypical cerebellum-type Creutzfeldt-Jakob disease: its relationship to "new variant" CJD and bovine spongiform encephalopathy. | 
| + | - | nl | Exp Biol Med (Maywood) 226(7):629-39 (2001) |
| 66 | 2009 | Transmissible mink encephalopathy - review of the etiology of a rare prion disease. | 
| + | - | nl | Folia Neuropathol 47(2):195-204 (2009) |
| 67 | 2009 | Cannibalism, kuru and anthropology. | 
| + | - | nl | Folia Neuropathol 47(2):138-44 (2009) |
| 68 | 2009 | Kuru and D. Carleton Gajdusek: a close encounter. | 
| + | - | nl | Folia Neuropathol 47(2):114-37 (2009) |
| 69 | 2009 | Thoughts on mammalian prion strains. | 
| + | - | nl | Folia Neuropathol 47(2):104-13 (2009) |
| 70 | 2009 | Reflections on a half-century in the field of transmissible spongiform encephalopathy. | 
| + | - | nl | Folia Neuropathol 47(2):95-103 (2009) |
| 71 | 2008 | Prion diseases: a riddle wrapped in a mystery inside an enigma. | 
| + | - | nl | Folia Neuropathol 46(2):93-116 (2008) |
| 72 | 2008 | Cell death and autophagy in prion diseases (transmissible spongiform encephalopathies). | 
| + | - | nl | Folia Neuropathol 46(1):1-25 (2008) |
| 73 | 2006 | Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 2. | 
| + | - | nl | Folia Neuropathol 44(2):102-10 (2006) |
| 74 | 2006 | Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 1. | 
| + | - | nl | Folia Neuropathol 44(2):93-101 (2006) |
| 75 | 2005 | Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence. | 
| + | - | nl | Folia Neuropathol 43(4):229-43 (2005) |
| 76 | 2004 | Prions: proteins as genes and infectious entities. | 
| + | - | nl | Genes Dev 18(5):470-85 (2004) |
| 77 | 2005 | Unraveling prion structures and biological functions. | 
| + | - | nl | Genome Biol 6(13):366 (2005) |
| 78 | 2005 | Prions and the blood and immune systems. | 
| + | - | nl | Haematologica 90(4):542-8 (2005) |
| 79 | 1997 | Human prion diseases and bovine spongiform encephalopathy (BSE). | 
| + | - | nl | Hum Mol Genet 6(10):1699-705 (1997) |
| 80 | 1995 | Prion protein isoforms, a convergence of biological and structural investigations. | 
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| 81 | 1976 | Scrapie: a review of its relation to human disease and ageing. | 
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| 82 | 2005 | Molecular neurology of prion disease. | 
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| 83 | 2004 | Prion diseases. | 
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| 84 | 1991 | The spongiform encephalopathies. | 
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| 85 | 2001 | The molecular pathology of CJD: old and new variants. | 
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| 86 | 1997 | Creutzfeldt-Jakob disease in the elderly. | 
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| 87 | 1979 | Slow viruses and chronic disease of the central nervous system. | 
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| 88 | 1978 | Creutzfeldt--Jakob disease. | 
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| 89 | 2008 | Prions in the environment: occurrence, fate and mitigation. | 
| + | - | nl | Prion 2(4):162-9 (2008) |
| 90 | 2007 | An emerging concept of prion infections as a form of transmissible cerebral amyloidosis. | 
| + | - | nl | Prion 1(4):223-7 (2007) |
| 91 | 2007 | Biological roles of prion domains. | 
| + | - | nl | Prion 1(4):228-35 (2007) |
| 92 | 2007 | A structural overview of the vertebrate prion proteins. | 
| + | - | nl | Prion 1(3):185-97 (2007) |
| 93 | 2007 | Prion stability. | 
| + | - | nl | Prion 1(3):170-8 (2007) |
| 94 | 2007 | Prion-prion interactions. | 
| + | - | nl | Prion 1(3):161-9 (2007) |
| 95 | 2007 | Yeast prions: evolution of the prion concept. | 
| + | - | nl | Prion 1(2):94-100 (2007) |
| 96 | 2007 | Prions and related phenomena. | 
| + | - | nl | Prion 1(2):81-2 (2007) |
| 97 | 2007 | Antiprion drugs as chemical tools to uncover mechanisms of prion propagation. | 
| + | - | nl | Prion 1(1):48-52 (2007) |
| 98 | 1998 | Prions. | 
| + | - | nl | Proc Natl Acad Sci U S A 95(23):13363-83 (1998) |
| 99 | 1994 | Inherited prion diseases. | 
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| 100 | 1994 | Neurodegeneration in humans caused by prions. | 
| + | - | nl | West J Med 161(3):264-72 (1994) |
| 101 | 1988 | Creutzfeldt-Jakob disease, 1988. | 
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| 102 | 2004 | Mammalian prion biology: one century of evolving concepts. | 
| + | - | nl | Cell 116(2):313-27 (2004) |
| 103 | 1998 | Prion protein biology. | 
| + | - | nl | Cell 93(3):337-48 (1998) |
| 104 | 2000 | Prions: Portable prion domains. | 
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| 105 | 2002 | The utility of prions. | 
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| 106 | 2002 | Prion diseases: pathogenesis and public health concerns. | 
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| 107 | 2002 | Cellular prion protein: on the road for functions. | 
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| 108 | 1999 | Prion protein interconversions and the transmissible spongiform encephalopathies. | 
| + | - | nl | Structure 7(10):R231-40 (1999) |
| 109 | 1994 | MR diagnosis of Creutzfeldt-Jakob disease: significance of high signal intensity of the basal ganglia. | 
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| 110 | 2005 | Isolated visual symptoms at onset in sporadic Creutzfeldt-Jakob disease: the clinical phenotype of the "Heidenhain variant". | 
| + | - | nl | Br J Ophthalmol 89(10):1341-2 (2005) |
| 111 | 2006 | Diffusion-weighted MR imaging of early-stage Creutzfeldt-Jakob disease: typical and atypical manifestations. | 
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| 112 | 2009 | Molecular pathology of human prion diseases. | 
| + | - | nl | Int J Mol Sci 10(3):976-99 (2009) |
| 113 | 2001 | Insights into the physiological function of cellular prion protein. | 
| + | - | nl | Braz J Med Biol Res 34(5):585-95 (2001) |
| 114 | 2001 | Variant Creutzfeldt-Jakob disease: a summary of current scientific knowledge in relation to public health. | 
| + | - | nl | CMAJ 165(1):51-8 (2001) |
| 115 | 2005 | Diffusion-weighted and fluid-attenuated inversion recovery imaging in Creutzfeldt-Jakob disease: high sensitivity and specificity for diagnosis. | 
| + | - | nl | AJNR Am J Neuroradiol 26(6):1551-62 (2005) |
| 116 | 2002 | Progress in understanding Creutzfeldt-Jakob disease. | 
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| 117 | 2002 | Emerging patterns of diffusion-weighted MR imaging in Creutzfeldt-Jakob disease: case report and review of the literature. | 
| + | - | nl | AJNR Am J Neuroradiol 23(4):550-6 (2002) |
| 118 | 2002 | Molecular biology of prions. | 
| + | - | nl | Acta Neurobiol Exp (Wars) 62(3):153-66 (2002) |
| 119 | 2002 | Variant Creutzfeldt-Jakob disease. | 
| + | - | nl | Acta Neurobiol Exp (Wars) 62(3):167-73 (2002) |
| 120 | 2002 | Bovine spongiform encephalopathy. Update. | 
| + | - | nl | Acta Neurobiol Exp (Wars) 62(3):183-95 (2002) |
| 121 | 2002 | Prion diseases: a dual view of the prion hypothesis as seen from a distance. | 
| + | - | nl | Acta Neurobiol Exp (Wars) 62(3):197-224; discussion 224-6 (2002) |
| 122 | 2008 | The tubulovesicular structures - the ultrastructural hallmark for all prion diseases. | 
| + | - | nl | Acta Neurobiol Exp (Wars) 68(1):113-21 (2008) |
| 123 | 2011 | Molecular pathology of human prion disease. | 
| + | - | nl | Acta Neuropathol 121(1):69-77 (2011) |
| 124 | 2011 | Molecular biology and pathology of prion strains in sporadic human prion diseases. | 
| + | - | nl | Acta Neuropathol 121(1):79-90 (2011) |
| 125 | 2011 | A novel seven-octapeptide repeat insertion in the prion protein gene (PRNP) in a Dutch pedigree with Gerstmann-Sträussler-Scheinker disease phenotype: comparison with similar cases from the literature. | 
| + | - | nl | Acta Neuropathol 121(1):59-68 (2011) |
| 126 | 2011 | Tau, prions and Aβ: the triad of neurodegeneration. | 
| + | - | nl | Acta Neuropathol 121(1):5-20 (2011) |
| 127 | 2009 | Prion protein misfolding and disease. | 
| + | - | nl | Curr Opin Struct Biol 19(1):14-22 (2009) |
| 128 | 2007 | Chronic wasting disease. | 
| + | - | nl | Biochim Biophys Acta 1772(6):610-8 (2007) |
| 129 | 2007 | The prion strain phenomenon: molecular basis and unprecedented features. | 
| + | - | nl | Biochim Biophys Acta 1772(6):681-91 (2007) |
| 130 | 2007 | The cellular prion protein (PrP(C)): its physiological function and role in disease. | 
| + | - | nl | Biochim Biophys Acta 1772(6):629-44 (2007) |
| 131 | 2011 | Self-propagation and transmission of misfolded mutant SOD1: prion or prion-like phenomenon? | 
| + | - | nl | Cell Cycle 10(11):1711 (2011) |
| 132 | 2004 | A new kind of prion: a modified protein necessary for its own modification. | 
| + | - | nl | Cell Cycle 3(2):100-3 (2004) |
| 133 | 2006 | Creutzfeldt-Jakob disease: a rare cause of dementia in elderly persons. | 
| + | - | nl | Clin Infect Dis 43(3):340-6 (2006) |
| 134 | 2008 | Review. Reflections on amyloidosis in Papua New Guinea. | 
| + | - | nl | Philos Trans R Soc Lond B Biol Sci 363(1510):3701-5 (2008) Westermark P |
| 135 | 2006 | The intriguing prion disorders. | 
| + | - | nl | Cell Mol Life Sci 63(19-20):2342-51 (2006) |
| 136 | 2009 | Prions: protein aggregation and infectious diseases. | 
| + | - | nl | Physiol Rev 89(4):1105-52 (2009) |
| 137 | 2007 | Prions. | 
| + | - | nl | Biochemistry (Mosc) 72(13):1519-36 (2007) |
| 138 | 2010 | Redox control of prion and disease pathogenesis. | 
| + | - | nl | Antioxid Redox Signal 12(11):1271-94 (2010) |
| 139 | 2006 | Self management of fatal familial insomnia. Part 1: what is FFI? | 
| + | - | nl | MedGenMed 8(3):65 (2006) |
| 140 | 2007 | Neuroimaging findings in human prion disease. | 
| + | - | nl | J Neurol Neurosurg Psychiatry 78(7):664-70 (2007) |
| 141 | 2010 | The prion hypothesis: from biological anomaly to basic regulatory mechanism. | 
| + | - | nl | Nat Rev Mol Cell Biol 11(12):823-33 (2010) |
| 142 | 2010 | Prion-like transmission of protein aggregates in neurodegenerative diseases. | 
| + | - | nl | Nat Rev Mol Cell Biol 11(4):301-7 (2010) |