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  • PARP
  • PARG
  • Mitochondria (BASKET)
  • Neuroprotective agents
  • Apoptosis
  • Excitotoxicity
  • Peroxynitrite
  • Redox (BASKET)
  • Nitric oxide NO
  • Brain injury
  • Nitrosative stress
  • PADPR
  • Insulator (Genetics)
  • DNMT1
  • Histone
  • DNA (Repair and Toxicology)
  • H2AX
  • Mammary gland (Neoplasia)
  • Diabetes mellitus (BASKET)
  • Endothelial dysfunction
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    		Citation
    12010PARP and PARG inhibitors--new therapeutic targets in cancer treatment.



    		+-nlPathol Oncol Res 16(4):469-78 (2010)
    22008Mitochondria, oxidative stress and PARP-1 network: a new target for neuroprotective effects of tetracyclines?



    		+-nlJ Physiol 586(10):2427-8 (2008)
    32009Drug targets for traumatic brain injury from poly(ADP-ribose)polymerase pathway modulation.



    		+-nlBr J Pharmacol 157(5):695-704 (2009)
    42010Targeting poly(ADP-ribose) polymerase activity for cancer therapy.



    		+-nlCell Mol Life Sci 67(21):3649-62 (2010)
    52008Transcriptional control by PARP-1: chromatin modulation, enhancer-binding, coregulation, and insulation.



    		+-nlCurr Opin Cell Biol 20(3):294-302 (2008)
    62009Epigenetics: poly(ADP-ribosyl)ation of PARP-1 regulates genomic methylation patterns.



    		+-nlFASEB J 23(3):672-8 (2009)
    72010The roles of PARP1 in gene control and cell differentiation.



    		+-nlCurr Opin Genet Dev 20(5):512-8 (2010)
    82010Histone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers.



    		+-nlClin Cancer Res 16(18):4532-42 (2010)
    92010Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer.



    		+-nlClin Cancer Res 16(18):4517-26 (2010)
    102010Poly(ADP-Ribose) polymerase inhibition: "targeted" therapy for triple-negative breast cancer.



    		+-nlClin Cancer Res 16(19):4702-10 (2010)
    112005Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme.



    		+-nlAntioxid Redox Signal 7(11-12):1568-80 (2005)
    122010PARP inhibitors in BRCA1-/BRCA2-associated and triple-negative breast cancers.



    		+-nlFuture Oncol 6(4):485-6 (2010)
    132005Poly(ADP-ribosyl)ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal.



    		+-nlGenes Dev 19(17):1951-67 (2005)
    142011Poly(ADP-ribose) polymerase-1 inhibition: preclinical and clinical development of synthetic lethality.



    		+-nlMol Med 17(7-8):854-62 (2011)



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