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  • MTOR
  • AMP activated protein kinase
  • LKB1
  • Phospholipase D
  • Neoplasia (Tumor biology and immunology)
  • Phosphatidic acid
  • Ephrin
  • Polycystin
  • Tuberin
  • Alcohol
  • TSC1
  • Kidney (Polycystic kidney disease)
  • Autophagy
  • Lymphangioleiomyomatosis
  • P70RSK
  • Rho
  • Cell migration
  • ARF
  • PLD2
  • PLD1
  • DOCK2
  • CDC42
  • IQGAP1
  • Biomembrane (Traffic)
  • HIF1alpha und HIF1 (BASKET)
  • Oxygen (Hypoxia)
  • Tuberculosis
  • Unfolded protein response
  • Leukemia (chronic lymphatic)
  • Lymphoma (BASKET)
  • Protein kinase C beta
  • Temsirolimus
  • Syk
  • Lymphoma (B cell diffuse large)
  • Enzastaurin
  • Everolimus
  • Fostamatinib
  • Interferon alpha and preliminary (BASKET)
  • Systemic lupus erythematosus
  • Caveolin and caveoles
  • Exosomes (Cell Secretion)
  • IGFBP3
  • P53
  • Protein kinase B Akt
  • PTEN
  • Endosom
  • TSC2
  • Sestrin1
  • Sestrin2
  • TSAP6
  • Chmp4C
  • DRAM
  • Rapamycin
  • CCI779
  • AP23573
  • Nr.Year

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    Citation
    12005Signaling by target of rapamycin proteins in cell growth control.



    +-nlMicrobiol Mol Biol Rev 69(1):79-100 (2005)
    22008Rapamycin and mTOR kinase inhibitors.



    +-nlJ Chem Biol 1(1-4):27-36 (2008)
    32005The mammalian target of the rapamycin (mTOR) kinase pathway: its role in tumourigenesis and targeted antitumour therapy.



    +-nlCell Mol Biol Lett 10(3):479-98 (2005)
    42007Expanding mTOR signaling.



    +-nlCell Res 17(8):666-81 (2007)
    52009Coordination of Ribosomal Protein and Ribosomal RNA Gene Expression in Response to TOR Signaling.



    +-nlCurr Genomics 10(3):198-205 (2009)
    62009The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents.



    +-nlTarget Oncol 4(2):135-42 (2009)
    72008Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies.



    +-nlMol Cancer Ther 7(6):1347-54 (2008)
    82005mTOR-targeted therapy of cancer with rapamycin derivatives.



    +-nlAnn Oncol 16(4):525-37 (2005)
    92007The mammalian target of rapamycin signaling pathway: twists and turns in the road to cancer therapy.



    +-nlClin Cancer Res 13(11):3109-14 (2007)
    102007The biology behind mTOR inhibition in sarcoma.



    +-nlOncologist 12(8):1007-18 (2007)
    112004Upstream and downstream of mTOR.



    +-nlGenes Dev 18(16):1926-45 (2004)
    122007Defining the role of mTOR in cancer.



    +-nlCancer Cell 12(1):9-22 (2007)
    132006TOR signaling in growth and metabolism.



    +-nlCell 124(3):471-84 (2006)
    142001Microtubules, motors, and mRNA localization mechanisms: watching fluorescent messages move.



    +-nlCell 107(6):707-10 (2001)
    152000TOR, a central controller of cell growth.



    +-nlCell 103(2):253-62 (2000) Schmelzle T
    162005TOR signaling: an odyssey from cellular stress to the cell growth machinery.



    +-nlCurr Biol 15(4):R139-41 (2005)
    172006The amino acid sensitive TOR pathway from yeast to mammals.



    +-nlFEBS Lett 580(12):2821-9 (2006)
    182010Updates of mTOR inhibitors.



    +-nlAnticancer Agents Med Chem 10(7):571-81 (2010)
    192006Therapeutic targets: MTOR and related pathways.



    +-nlCancer Biol Ther 5(9):1065-73 (2006)
    202003The molecular target of rapamycin (mTOR) as a therapeutic target against cancer.



    +-nlCancer Biol Ther 2(4 Suppl 1):S169-77 (2003)
    212009LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.



    +-nlActa Physiol (Oxf) 196(1):65-80 (2009)
    222009Amino acid regulation of TOR complex 1.



    +-nlAm J Physiol Endocrinol Metab 296(4):E592-602 (2009)
    232009Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells.



    +-nlBiochim Biophys Acta 1791(9):949-55 (2009)
    242010Eph receptor and mTOR pathway crosstalk: implications for cancer.



    +-nlCell Cycle 9(11):2053-4 (2010)
    252006Regulation of mTOR by polycystin-1: is polycystic kidney disease a case of futile repair?



    +-nlCell Cycle 5(21):2425-9 (2006)
    262010Reduced mortality and moderate alcohol consumption: the phospholipase D-mTOR connection.



    +-nlCell Cycle 9(7):1291-4 (2010)
    272008Aging: ROS or TOR.



    +-nlCell Cycle 7(21):3344-54 (2008)
    282008Deconstructing feedback-signaling networks to improve anticancer therapy with mTORC1 inhibitors.



    +-nlCell Cycle 7(24):3805-9 (2008)
    292007All roads lead to mTOR: integrating inflammation and tumor angiogenesis.



    +-nlCell Cycle 6(24):3011-4 (2007)
    302006The mTOR pathway in the control of protein synthesis.



    +-nlPhysiology (Bethesda) 21(-):362-9 (2006)
    312010Of mice and men: therapeutic mTOR inhibition in polycystic kidney disease.



    +-nlJ Am Soc Nephrol 21(3):390-1 (2010) Pei Y
    322009The role of the mammalian target of rapamycin (mTOR) in renal disease.



    +-nlJ Am Soc Nephrol 20(12):2493-502 (2009)
    332010Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapy.



    +-nlProc Am Thorac Soc 7(1):48-53 (2010)
    342009mTOR signaling at a glance.



    +-nlJ Cell Sci 122(Pt 20):3589-94 (2009)
    352010Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony.



    +-nlJ Biol Chem 285(19):14071-7 (2010)
    362010New concepts in phospholipase D signaling in inflammation and cancer.



    +-nlScientificWorldJournal 10(-):1356-69 (2010)
    372010An emerging role for IQGAP1 in regulating protein traffic.



    +-nlScientificWorldJournal 10(-):944-53 (2010)
    382011Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: drug discovery for targeting the tumor microenvironment.



    +-nlJ Pharmacol Sci 115(4):446-52 (2011)
    392010Signal transduction inhibitor therapy for lymphoma.



    +-nlHematology Am Soc Hematol Educ Program 2010(-):265-70 (2010)
    402010mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus?



    +-nlDiscov Med 9(46):173-8 (2010)
    412010TOR-dependent control of autophagy: biting the hand that feeds.



    +-nlCurr Opin Cell Biol 22(2):157-68 (2010)
    422011Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy.



    +-nlJ Clin Invest 121(4):1231-41 (2011)
    432010p53 regulation of the IGF-1/AKT/mTOR pathways and the endosomal compartment.



    +-nlCold Spring Harb Perspect Biol 2(2):a001057 (2010)
    442011Regulation of autophagy by lysosomal positioning.



    +-nlAutophagy 7(8):927-8 (2011)
    452008The role of TOR in autophagy regulation from yeast to plants and mammals.



    +-nlAutophagy 4(7):851-65 (2008)
    462010mTOR regulation of autophagy.



    +-nlFEBS Lett 584(7):1287-95 (2010)
    472004Mammalian target of rapamycin inhibition.



    +-nlClin Cancer Res 10(18 Pt 2):6382S-7S (2004)
    482004Mammalian target of rapamycin inhibition as therapy for hematologic malignancies.



    +-nlCancer 100(4):657-66 (2004)
    492007Regulation of mTOR by phosphatidic acid?



    +-nlCancer Res 67(1):1-4 (2007)
    502004Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer.



    +-nlBr J Cancer 91(8):1420-4 (2004)
    512010Prospects for mTOR inhibitor use in patients with polycystic kidney disease and hamartomatous diseases.



    +-nlClin J Am Soc Nephrol 5(7):1312-29 (2010)



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