| Nr. | Year OPEN | Title | users say> | rate good | rate bad | no link | Citation |
HedgehogMedulloblastomaWnt beta Catenin TCFEpithelio mesenchymal transitionStomach (Anatomy)Stomach (Development)Gut (Development)P53GLIDenys Drash syndromeFrasier s syndromeReceptor (FSH)Receptor (GnRH)Androgens (Hypogonadotropic hypogonadism)Hypophysis (Development)InfertilityLeptinAdrenal gland (Hyperplasia congenital)Spermatogenesis and spermatozoonStARSteroid hormones (Synthesis)WT1Kallmann s syndrome5 alpha ReductaseKALHESX1LHX3 Lim3Pituitary gland (Insufficiency Panhypopituitarism)LHX4PROP1Puberty (Delayed)FolliculogenesisReceptor (LH)Testis (Development)SrySF1SOX9Campomelic dysplasiaP450 side chain cleavage3 beta hydroxysteroid dehydrogenase217 alpha hydroxylase 17 20 lyase3 beta hydroxysteroid dehydrogenase3Receptor (Androgen)AMHAMHR2Insulin like 3 Relaxin like factorDAX1 NR0B1ERRORCholesterolCiliaStem cell (Neoplasia)| 1 | 1998 | Hedgehog and patched in neural development and disease. | 
| + | - | nl | Neuron 21(6):1243-57 (1998) |
| 2 | 2010 | Sonic Hedgehog signaling in the mammalian brain. | 
| + | - | nl | J Neurochem 113(3):576-90 (2010) |
| 3 | 2010 | Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies. | 
| + | - | nl | Pharmacol Rev 62(3):497-524 (2010) |
| 4 | 2002 | Roughing up Smoothened: chemical modulators of hedgehog signaling. | 
| + | - | nl | J Biol 1(2):8 (2002) |
| 5 | 2002 | The therapeutic potential of modulators of the Hedgehog-Gli signaling pathway. | 
| + | - | nl | J Biol 1(2):9 (2002) |
| 6 | 2010 | Small-molecule modulators of the Sonic Hedgehog signaling pathway. | 
| + | - | nl | Mol Biosyst 6(1):44-54 (2010) |
| 7 | 2006 | The hedgehog signaling pathway in cancer. | 
| + | - | nl | Clin Cancer Res 12(20 Pt 1):5924-8 (2006) |
| 8 | 2005 | Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics. | 
| + | - | nl | Cancer Res 65(12):4975-8 (2005) |
| 9 | 1999 | The hedgehog signalling pathway in tumorigenesis and development. | 
| + | - | nl | Oncogene 18(55):7844-51 (1999) |
| 10 | 2005 | Hedgehog signaling pathway and gastric cancer. | 
| + | - | nl | Cancer Biol Ther 4(10):1050-4 (2005) |
| 11 | 1999 | Actions of hedgehog proteins on skeletal cells. | 
| + | - | nl | Crit Rev Oral Biol Med 10(4):477-86 (1999) |
| 12 | 2007 | Hedgehog signaling in development and homeostasis of the gastrointestinal tract. | 
| + | - | nl | Physiol Rev 87(4):1343-75 (2007) |
| 13 | 2007 | Hedgehog signaling. | 
| + | - | nl | J Cell Sci 120(Pt 1):3-6 (2007) |
| 14 | 2003 | Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. | 
| + | - | nl | Development 130(22):5297-305 (2003) |
| 15 | 2009 | Making a grade: Sonic Hedgehog signalling and the control of neural cell fate. | 
| + | - | nl | EMBO J 28(5):457-65 (2009) |
| 16 | 1998 | Transducing Hedgehog: the story so far. | 
| + | - | nl | EMBO J 17(13):3505-11 (1998) |
| 17 | 2008 | The role of kinases in the Hedgehog signalling pathway. | 
| + | - | nl | EMBO Rep 9(4):330-6 (2008) |
| 18 | 2008 | Hedgehog: functions and mechanisms. | 
| + | - | nl | Genes Dev 22(18):2454-72 (2008) |
| 19 | 2001 | Hedgehog signaling in animal development: paradigms and principles. | 
| + | - | nl | Genes Dev 15(23):3059-87 (2001) |
| 20 | 2008 | The Hedgehog protein family. | 
| + | - | nl | Genome Biol 9(11):241 (2008) |
| 21 | 2006 | New "hogs" in Hedgehog transport and signal reception. | 
| + | - | nl | Cell 125(3):435-8 (2006) |
| 22 | 2000 | Transducing the hedgehog signal. | 
| + | - | nl | Cell 103(3):371-4 (2000) |
| 23 | 2000 | More surprises in the Hedgehog signaling pathway. | 
| + | - | nl | Cell 100(2):185-8 (2000) |
| 24 | 1998 | Hedgehog and Spitz: making a match between photoreceptor axons and their targets. | 
| + | - | nl | Cell 95(5):587-90 (1998) |
| 25 | 1998 | Protein splicing of inteins and hedgehog autoproteolysis: structure, function, and evolution. | 
| + | - | nl | Cell 92(1):1-4 (1998) |
| 26 | 1995 | The long and short of hedgehog signaling. | 
| + | - | nl | Cell 81(3):313-6 (1995) |
| 27 | 1995 | Hedgehog and beyond. | 
| + | - | nl | Cell 80(4):517-20 (1995) |
| 28 | 1996 | Sonic hedgehog: making the gradient. | 
| + | - | nl | Chem Biol 3(1):13-6 (1996) |
| 29 | 2007 | Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused. | 
| + | - | nl | Curr Biol 17(15):1326-33 (2007) |
| 30 | 2004 | Hedgehog signaling: measuring ligand concentrations with receptor ratios. | 
| + | - | nl | Curr Biol 14(20):R889-91 (2004) |
| 31 | 2004 | Hedgehog signaling: iguana debuts as a nuclear gatekeeper. | 
| + | - | nl | Curr Biol 14(16):R668-70 (2004) |
| 32 | 1998 | Sonic hedgehog regulates branching morphogenesis in the mammalian lung. | 
| + | - | nl | Curr Biol 8(19):1083-6 (1998) |
| 33 | 1995 | Morphogenetic signalling. Responses to hedgehog. | 
| + | - | nl | Curr Biol 5(6):580-2 (1995) |
| 34 | 2008 | Hedgehog signaling in development and cancer. | 
| + | - | nl | Dev Cell 15(6):801-12 (2008) |
| 35 | 2005 | Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs. | 
| + | - | nl | Dev Cell 8(2):143-51 (2005) |
| 36 | 2005 | Shifted from Wnt to Hedgehog signaling pathways. | 
| + | - | nl | Mol Cell 17(3):321-2 (2005) Han C |
| 37 | 2000 | The sonic hedgehog-patched-gli pathway in human development and disease. | 
| + | - | nl | Am J Hum Genet 67(5):1047-54 (2000) |
| 38 | 2007 | A general role of hedgehog in the regulation of proliferation. | 
| + | - | nl | Cell Cycle 6(2):156-9 (2007) |
| 39 | 2005 | Hedgehogs as negative regulators of the cell cycle. | 
| + | - | nl | Cell Cycle 4(9):1139-40 (2005) |
| 40 | 2006 | Hedgehog morphogen in cardiovascular disease. | 
| + | - | nl | Circulation 114(18):1985-91 (2006) |
| 41 | 2003 | How a Hedgehog might see holoprosencephaly. | 
| + | - | nl | Hum Mol Genet 12 Spec No 1(-):R15-25 (2003) |
| 42 | 2008 | Hedgehog signalling in endocrine development and disease. | 
| + | - | nl | J Endocrinol 198(3):439-50 (2008) |
| 43 | 2003 | Sonic hedgehog. | 
| + | - | nl | Mol Pathol 56(3):129-31 (2003) |
| 44 | 2000 | From fruitflies to mammals: mechanisms of signalling via the Sonic hedgehog pathway in lung development. | 
| + | - | nl | Respir Res 1(1):30-5 (2000) |
| 45 | 2008 | Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review). | 
| + | - | nl | Int J Mol Med 22(3):271-5 (2008) |
| 46 | 2001 | Clinical aspects of disrupted Hedgehog signaling (Review). | 
| + | - | nl | Int J Mol Med 8(4):445-52 (2001) |
| 47 | 2008 | Implications of hedgehog signaling antagonists for cancer therapy. | 
| + | - | nl | Acta Biochim Biophys Sin (Shanghai) 40(7):670-80 (2008) |
| 48 | 2008 | The adventures of sonic hedgehog in development and repair. IV. Sonic hedgehog processing, secretion, and function in the stomach. | 
| + | - | nl | Am J Physiol Gastrointest Liver Physiol 294(5):G1105-8 (2008) |
| 49 | 2008 | The adventures of sonic hedgehog in development and repair. II. Sonic hedgehog and liver development, inflammation, and cancer. | 
| + | - | nl | Am J Physiol Gastrointest Liver Physiol 294(3):G595-8 (2008) |
| 50 | 2008 | The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease. | 
| + | - | nl | Am J Physiol Gastrointest Liver Physiol 294(2):G363-7 (2008) |
| 51 | 2008 | The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity. | 
| + | - | nl | Am J Physiol Gastrointest Liver Physiol 294(4):G844-9 (2008) |
| 52 | 2010 | Protecting the hedgerow: p53 and hedgehog pathway interactions. | 
| + | - | nl | Cell Cycle 9(3):506-11 (2010) |
| 53 | 2007 | Shh signaling and pancreatic cancer: implications for therapy? | 
| + | - | nl | Cell Cycle 6(13):1553-7 (2007) |
| 54 | 2007 | Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy. | 
| + | - | nl | Cell Cycle 6(20):2458-63 (2007) |
| 55 | 2002 | Genetic causes of human reproductive disease. | 
| + | - | nl | J Clin Endocrinol Metab 87(6):2447-54 (2002) |
| 56 | 2002 | Cholesterol modification of Hedgehog family proteins. | 
| + | - | nl | J Clin Invest 110(5):591-6 (2002) |
| 57 | 2010 | Primer and interviews: Diverse connections between primary cilia and Hedgehog signaling. | 
| + | - | nl | Dev Dyn 239(4):1255-62 (2010) |
| 58 | 2010 | Targeting Hedgehog--a cancer stem cell pathway. | 
| + | - | nl | Clin Cancer Res 16(12):3130-40 (2010) |